Bioactive Constituents from the Bryophyta <i>Hypnum plumaeforme</i>

Li, Jianlin; Wie, Lai-Lai; Chen, Chen; Liu, Di; Gu, Yu-Qin; Duanmu, Jiaxin; Chen, Guangtong; Song, Yan

doi:10.1002/cbdv.202000552

Cited by 9 publications

(17 citation statements)

References 25 publications

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“…Biflavonoids are always comprised of two units of flavonoids by a direct connection between the rings (A, B or C) of each flavonoid unit (He et al 2021). Biflavonoids were only found in the Dicranidae and Bryidae subclasses, mainly in Dicranales (Geiger et al 1997;Lindberg et al 1974;Markham 1988;Osterdahl & Lindberg 1977;Sala-Carvalho et al 2022;Waterman et al 2017;Zinsmeister et al 1996), Bartramiales (Basile et al 1999;Geiger et al 1997;Geiger & Bokel 1989;Kato-Noguchi 2016;L ópez-Sa ´ez 1996;Salm et al1993;Seeger et al 1991Seeger et al , 1993a, Bryales (Anhut et al 1989a,b;Geiger 1987;Geiger et al 1997Geiger et al , 1988Stein & Zinsmeister 1991), Aulacomniales (Geiger et al 1997;Hahn et al 1995), and Hypnales (Becker et al 1986;Brinkmeier et al 2000;Geiger et al 1997Geiger et al , 1988Li et al 2020;Seeger et al 1993bSeeger et al , 1992aSeeger et al , 1990Sievers et al 1992), but there were also reports of these compunds in Grimmiales (Geiger et al 1997), Hedwigiales (Zinsmeister et al 1996), and Rhizogoniales (Geiger & Seeger 2000;Zinsmeister et al 1996) (Fig. 9).…”

Section: Resultsmentioning

confidence: 99%

A chemistry overview of the beautiful miniature forest known as mosses

2023

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The bryophytes are the second largest group of land plants and are represented by three lineages: Marchantyophyta (liverworts), Anthocerotophyta (hornworts), and Bryophyta (mosses). They occupy a wide variety of habitats, from deserts to Antarctica, and exercise great ecological importance. These facts and their wide use in traditional medicine raise the question of what is known about moss chemistry. This paper gathered studies from the last 52 years about the compounds identified in mosses, aiming to address the following questions: Are mosses chemically under-studied? How many families, genera, and species of mosses have been chemically studied? Which continent and countries have been responsible for the majority of these studies? A literature search was performed in major scientific databases, using a combination of keywords. A total of 199 papers were compiled, of which 45% were published during the last decade. Only a small percentage of moss species has been studied, mostly from Europe and Asia. Dicranales and Hypnales are the most studied orders. In general, fatty acids and flavonoids are the most commonly reported classes of compounds. Biflavonoids and triflavonoids are detected mainly in derived clades of mosses, while coumarins are most reported for basal groups. Akthough only a small percentage of moss species has been chemically studied, most of these studies were published in the last decade—there has been a 135% increase in the number of reported compounds in the last 13 years. The emergence of new equipment, which can produce high-resolution spectra with small amounts of sample, combined with bioinformatics tools, has undoubtedly contributed to the increase of chemical investigation of mosses. Also, advances in the identification and phylogenetics of moss groups are contributing to a better understanding of them generally, which should lead also to increased study of moss chemistry.

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Section: Resultsmentioning

confidence: 99%

A chemistry overview of the beautiful miniature forest known as mosses

2023

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“…Oryzae [12] and Magnaporthe oryzae [13], which cause rice bacterial leaf streak, have been effectively inhibited using bio-extracts enriched with active metabolites from medicinal plants [12,13]. These bioactive compounds play crucial roles due to their antibacterial, antifungal, and antiviral properties, which com- To date, seven momilactone molecules have been identified, namely momilactones A (MA), B (MB), C (MC), D (MD), E (ME), and F (MF) [24][25][26][27][28][29]. Among these, only MA (1), MB (2), and MC (3) as shown in Figure 2 have been definitively identified in rice husks [24,26,27].…”

Section: Introductionmentioning

confidence: 99%

Potential Momilactones in Rice Stress Tolerance and Health Advantages

Rayee,

Anh,

Khanh

et al. 2024

Agronomy

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The aim of this review was to provide an updated outlook on the relevance of momilactones in rice during the 50 years since their discovery. Momilactones A (MA) and B (MB) were initially extracted from rice husks in 1973 and have since been identified in various parts of the rice plant including leaves, bran, straw, roots, and root exudates. The biosynthesis of these compounds in rice initiates from geranylgeranyl diphosphate (GGDP) and progresses through several cyclization stages. The genes governing the synthesis of MA and MB are located on chromosome 4 within the rice genome. Concentrations of these compounds vary across different parts of the rice plant, ranging from 2 to 157 μg/g. Notably, Japonica rice varieties tend to have higher levels of MA and MB (157 and 83 μg/g, respectively) compared to Indica varieties (20.7 and 4.9 μg/g, respectively). There is a direct correlation between the levels of MA and MB and the increase in antioxidant activity, protein, and amylose content in rice grains. The production of these compounds is enhanced under environmental stresses such as drought, salinity, chilling, and UV exposure, indicating their potential role in rice’s tolerance to these conditions. MA and MB also demonstrate allelopathic, antibacterial, and antifungal properties, potentially improving the resilience of rice plants against biotic stressors. Although their antioxidant activity is modest, they effectively inhibit leukemia cells at a concentration of 5 µM. They also show promise in diabetes management by inhibiting enzymes like α-amylase (with IC50 values of 132.56 and 129.02 mg/mL, respectively) and α-glucosidase (with IC50 values of 991.95 and 612.03 mg/mL, respectively). The therapeutic qualities of MA and MB suggest that cultivating rice varieties with higher concentrations of these compounds, along with developing their derivatives, could benefit the pharmaceutical industry and enhance treatments for chronic diseases. Consequently, breeding rice cultivars with increased momilactone levels could offer substantial advantages to rice farmers.

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“…Icacinlactone M ( 8 ), 14 α- methoxyhumirianthol ( 16 ), and annonalide ( 17 ) were found from Icacina oliviformis ( Zhao et al, 2015a ) for the first time ( Sun et al, 2021 ). Besides ( Graebner et al, 2000 ), humirianthol ( 12 ) ( Li et al, 2020 ), icacinol ( 14 ), 17-hydroxyicacinol ( 15 ), 14 α -methoxyhumirianthol ( 16 ), and annonalide ( 17 ) showed cytotoxic activities ( Onakpa et al, 2014 ) toward human cancer cell lines. These compounds were also obtained from the tuber of Icacina oliviformis ( Zhou et al, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

A Synthetic View on Momilactones and Related 9β-H Pimarane Skeleton Diterpenoids

Zhang

Liu

et al. 2022

Front. Chem.

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Allelochemicals are secondary metabolites produced from plants and used to prevent and control the invasion of other plants and microorganisms, with broad application prospects in crop protection. Structurally, momilactones belong to 9β-H pimarane diterpenoids, one of rice’s significant allelochemicals with anti-weeds and antibacterial activity. Rare studies have been reported with the synthesis challenges of the unique 9β-H pimarane skeleton. Hence, synthetic strategies of momilactones and related 9β-H pimarane skeleton are reviewed from 1984 to 2021.

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Bioactive Constituents from the Bryophyta Hypnum plumaeforme

Cited by 9 publications

References 25 publications

A chemistry overview of the beautiful miniature forest known as mosses

A chemistry overview of the beautiful miniature forest known as mosses

Potential Momilactones in Rice Stress Tolerance and Health Advantages

A Synthetic View on Momilactones and Related 9β-H Pimarane Skeleton Diterpenoids

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