Bioactive Compounds from Natural Sources

Role of fungal enzymes in the synthesis of pharmaceutically important scaffolds: a green approach

“…Resveratrol has gained considerable popularity due to its various beneficial biological properties, including anti-inflammatory effects, as well as its potential for preventing cardiovascular diseases and colon cancer. 47,48 Other stilbenoids, such as isorhapontigenin, have also shown promising pharmacological properties, 49 drawing attention to dimeric and oligomeric stilbenoids. These compounds are found in a limited distribution within the plant kingdom and have recently been recognized as natural products with noteworthy biological activities, including antioxidant, antimicrobial, anti-inflammatory, and antitumor effects.…”

Laccase-mediated synthesis of bioactive natural products and their analogues

“…Resveratrol has reached an impressive level of popularity mainly due to a variety of beneficial biological properties, including anti-inflammatory action as well as prevention of cardiovascular diseases and colon cancer. 107,108 Further stilbenoids, including isorhapontigenin (35), have been reported for promising pharmacological properties, 109 and this attracted the attention of researchers also to the dimeric and oligomeric stilbenoids, narrowly distributed in the Plant Kingdom, and only lately recognized as natural products with significant biological properties, including antioxidant, antimicrobial, anti-inflammatory and antitumor activity. 110,111 It is generally accepted that the biosynthesis of dimeric stilbenoids proceeds through phenolic oxidative coupling, although different mechanisms have been proposed.…”