Bilateraler simultaner retinaler Zentralvenenverschluss bei Protein-S-Mangel

Tóth, Gábor; Sándor, Gábor László; Reichel, Christoph; Domján, Gyula; Nagy, Zoltán Zsolt; Ecsedy, Mónika

doi:10.1007/s00347-015-3234-1

Cited by 3 publications

(2 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Bilateral CRVO is exceedingly rare, and its presentation has been documented in only a handful of case studies in association with hypercoagulable and hyperviscous states. [6][7][8] In the rare case of bilateral CRVO, the differential diagnosis should include systemic lupus erythematosus, acute myeloid leukemia, Waldenstrom's macroglobinemia, antiphospholipid antibody syndrome, and dysproteinemias. 9 Multiple myeloma is most commonly diagnosed in the presence of hypercalcemia, renal insufficiency, anemia, and the presence of osteolytic bone lesions on skeletal radiography.…”

Section: Discussionmentioning

confidence: 99%

Bilateral Central Retinal Vein Occlusion as a First Presentation of Multiple Myeloma: A Case Report

Tandlich

Williamson

2022

Clinical Practice and Cases in Emergency Medicine

View full text Add to dashboard Cite

Introduction: Acute presentation of multiple myeloma in the emergency department (ED) is an uncommon yet life-threatening clinical entity. Case Report: A 42-year-old male presented to the ED with severe generalized fatigue and vision changes most notable in his left eye. Bilateral central retinal vein occlusion (CRVO) was diagnosed on dilated fundus exam in the ED. Conclusion: The most common cause of CRVO in adults over age 50 is vascular disease, but in younger adults, conditions of systemic inflammation or hyperviscosity must be considered. Diagnosis of CRVO requires emergent ophthalmology consultation and further treatment with phototherapy, steroids, and potentially anti-vascular endothelial growth factor. Ultimately, patients require hematology/oncology and ongoing management of acute hyperviscosity syndrome. We present this case to increase awareness surrounding this diagnosis among emergency physicians. Multiple myeloma should be considered in young patients who present to the ED with bilateral CRVO, acute renal failure, and symptomatic anemia.

show abstract

Section: Discussionmentioning

confidence: 99%

Bilateral Central Retinal Vein Occlusion as a First Presentation of Multiple Myeloma: A Case Report

Tandlich

Williamson

2022

Clinical Practice and Cases in Emergency Medicine

View full text Add to dashboard Cite

show abstract

“…Diabetes mellitus (DM) is one of the most common causes of blindness and severe visual impairment in middle-aged people. The most dangerous and common complications of DM leading to enucleation are proliferative diabetic retinopathy and retinal vein occlusion [22, 23]. Enucleation due to systemic diseases has decreased remarkably in recent decades [12].…”

Section: Discussionmentioning

confidence: 99%

Clinicopathological Review of 547 Bulbar Enucleations in Hungary (2006–2017)

Tóth

Szentmáry

Sándor

et al. 2019

Journal of Ophthalmology

View full text Add to dashboard Cite

Purpose. To analyse current clinicopathological enucleation indications in a large third-referral centre in a developed country (Hungary) over a period of 12 years. Methods. Retrospective review was performed on 547 enucleated eyes of 543 patients (48.6% males, age 52.7 ± 24.5 years) who were operated on between 2006 and 2017 at the Department of Ophthalmology of Semmelweis University, in Budapest, Hungary. For each subject, clinicopathological data, including patient demographics, indications for enucleation, B-scan ultrasound reports, operative details, and histopathological analyses, were reviewed. Primary enucleation indications were classified into trauma, tumours, systemic diseases, surgical diseases, infections or inflammations, miscellaneous diseases, and unclassifiable groups. Clinical immediate enucleation indications were classified as tumours, atrophia or phthisis bulbi, infection or inflammation, painful blind eye due to glaucoma, acute trauma, threatening or spontaneous perforation, cosmetic causes, and expulsive bleeding. Results. The most common primary enucleation indications were tumours (47.3%), trauma (16.8%), surgical diseases (15.7%), infection or inflammation (11.6%), systemic diseases (5.1%), miscellaneous diseases (2.0%), and unclassifiable diseases (1.5%). Clinical immediate enucleation indications were tumours (46.1%), atrophia or phthisis bulbi (18.5%), infection or inflammation (18.5%), painful blind eye due to glaucoma (11.2%), acute trauma (3.7%), threatening or spontaneous perforation (1.3%), cosmetic reasons (0.5%), and expulsive bleeding (0.4%). Conclusions. Intraocular tumours represent the most common clinicopathological indication for ocular enucleation in our study population. Following ocular trauma and systemic diseases, the rate of enucleation decreased in the last decade, compared to those previously reported in other developed countries. However, changes were not observed for surgical diseases, infectious and inflammatory causes, or for miscellaneous and unclassified diseases. Orbital implant financing should be increased to ensure better postoperative aesthetic rehabilitation, following enucleation in Hungary.

show abstract

Multiple thrombophile Risikomarker bei Patienten ≺65 Jahre mit venösen retinalen Gefäßverschlüssen

et al. 2017

View full text Add to dashboard Cite

Multiple thrombophilic disorders are associated with the development of RVO among patients younger than 65 years of age. Moreover, our results suggest that patients with RVO associated with underlying combined thrombophilic defects are at increased risk for RVO recurrence. Further studies are required to analyze whether the diagnosis of combined thrombophilic defects among RVO patients could be a predictor for RVO recurrence.

show abstract

Bilateraler simultaner retinaler Zentralvenenverschluss bei Protein-S-Mangel

Abstract: Thrombophilia assays and taking a thorough medical history should be performed.

Cited by 3 publications

References 11 publications

Bilateral Central Retinal Vein Occlusion as a First Presentation of Multiple Myeloma: A Case Report

Bilateral Central Retinal Vein Occlusion as a First Presentation of Multiple Myeloma: A Case Report

Clinicopathological Review of 547 Bulbar Enucleations in Hungary (2006–2017)

Multiple thrombophile Risikomarker bei Patienten ≺65 Jahre mit venösen retinalen Gefäßverschlüssen

Contact Info

Product

Resources

About