Multiple thrombophile Risikomarker bei Patienten ≺65 Jahre mit venösen retinalen Gefäßverschlüssen

Abstract

Multiple thrombophilic disorders are associated with the development of RVO among patients younger than 65 years of age. Moreover, our results suggest that patients with RVO associated with underlying combined thrombophilic defects are at increased risk for RVO recurrence. Further studies are required to analyze whether the diagnosis of combined thrombophilic defects among RVO patients could be a predictor for RVO recurrence.

Risk factor for retinal vein occlusion: A case control study

“…The second patient had 21 years presented PS deficiency in combination with factor V Leiden mutation. These results were concordant with the German study concluding that the combination of many prothrombotic disorders in young people represent a risk factor to develop RVO [37].…”

“…16.7% of our population presented combined disorder similarly to a German study in which the frequency was at 18.0% [37]. In our study the association of G1691A factor V polymorphism and polymorphism C677T MTHFR was diagnosed in a 20-year female without any risk factor of RVO.…”

“…No association [36] 71.0 No association [37] 38.1 Signifiant association (p<0.005) Our study 7.0 No association…”