BackgroundThe Optic nerve is rarely involved after sheep brain anti-rabies vaccination in the form of retrobulbar neuritis or papillitis. Bilateral neuroretinitis after chick embryo cell antirabies vaccination has not been reported.Case presentationWe report the case of a 56 year old male who developed bilateral neuro-retinitis following three injections of antirabies vaccine prepared from the chick embryo.ConclusionThe chick embryo cell antirabies vaccine can cause bilateral neuroretinits which has not been reported previously.