Bilateral Amyloidosis of the Ureter Associated with Carcinoma

Mullin, Edward M.; Trostle, Douglas R.; Fetzer, Arthur E.; Jaffe, John S.; Suraci, Aldo; Shane, John J.

doi:10.1016/s0022-5347(17)50086-5

Cited by 13 publications

(8 citation statements)

References 5 publications

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“…However, a localized variety of the disease also exists, in which deposits are limited to a single organ, such as the respiratory tract or the genitourinary tract [1]. On the grounds of etiology, amyloidosis may be classified as ''primary'', when no causative agent can be implicated, or ''secondary'', when a chronic inflammatory disorder, such as inflammatory bowel disease, leprosy, tuberculosis, syphilis, rheumatoid arthritis, osteomyelitis or multiple myeloma, is the underlying basis for its development [2].…”

Section: Discussionmentioning

confidence: 99%

Anurea caused by primary amyloidosis of the lower third of the ureters, the ureterovesical junction and the urinary bladder

2004

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Section: Discussionmentioning

confidence: 99%

Anurea caused by primary amyloidosis of the lower third of the ureters, the ureterovesical junction and the urinary bladder

2004

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“…Thus, more invasive surgical intervention was not readily acceptable. We could not prove the amyloid deposition in the stenotic lesion of the right ureter of both cases, but localized amyloidosis was strongly suspected from their clinical courses and roentogenologic findings 9,10,11,12,13 . In case 1, percutaneous nephrostomy was employed for the residual right kidney with hydronephrosis and the patient's renal function was saved.…”

Section: Discussionmentioning

confidence: 70%

“…The age of the reported patients ranged from 12 to 81 years (average: 55) 6 . In most patients, the disease is localized unilaterally to the distal part of the ureter 6 , but sequential bilateral involvement may occur occasionally, sometimes resulting in anuria 9,10,11,12,13 . Detailed histopathological findings were obtained from a significant number of patients: on gross examination, the involved ureter was indurated and thickened, and the ureteral mucosa had an irregular surface, sometimes accompanied by focal hemorrhages 12 .…”

Section: Discussionmentioning

confidence: 99%

Bilateral localized amyloidosis of the ureters: clinicopathology and therapeutic approaches in two cases

Fushimi

Takei

Touma

et al. 2004

Amyloid

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Localized amyloidosis in the ureter is a rare condition, in which immunoglobulin light chain is locally synthesized, causing thickening of ureteric walls by deposits of immunoglobulin-related amyloid. Since the clinical features of ureteral amyloidosis with ureteric stricture and/or hydroureteronephrosis closely resemble those of malignancy involving the ureters, nephroureterctomy is usually performed for this disease. We describe two aged patients with localized amyloidosis on the bilateral ureters. In both cases, left hydronephrosis with left ureteral stricture was found. They were treated with total nephroureterctomy and Alambda amyloid deposition was confirmed in the resected ureters. Several months later right ureteral stenosis was found. One patient was treated with percutaneous nephrostomy to preserve his renal function and the other with corticosteroids. This appeared to result in significant regression of the stenotic lesion. In both cases, all examinations for systemic involvement of organs were negative. Corticosteroids may be of use in treating immunoglobulin-derived localized amyloidosis in the ureters.

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“…3 Only Mullin and colleagues reported 1 case of ureteral amyloidosis associated with low-grade transitional cell carcinoma. 19 Subsequent follow-up was also uneventful.…”

Section: Discussionmentioning

confidence: 93%

“…Gilbert and McDonald reported the first English literature about localized ureteric amyloidosis in 1952. 6 The mean age at diagnosis of the reported cases was 58.3, and ranged from 17 to 81. Of these cases, 72.9 % (35/48) of patients were over 50 years old.…”

Section: Discussionmentioning

confidence: 99%

Localized amyloidosis of the ureter: A case report and literature review

Ding

et al. 2013

CUAJ

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case report E764Cite as: Can Urol Assoc J 2013;7(11-12):e764-7. http://dx.doi.org/10.5489/cuaj.576 Published online November 8, 2013. AbstractLocalized amyloidosis of the ureter is a rare disease and can easily be confused with a neoplasm. We report the case of a 55-year-old woman who presented with loin pain and painless gross hematuria. We also reviewed the English literature about localized ureteral amyloidosis. Middle-aged women were likely to suffer from this disorder. Loin pain and hematuria were the main clinical features. There were no specific performance on radiologic imaging and ureteral calcification was not widespread. Compared to upper ureter and middle ureter, the lower ureter was the easiest involved part. Nephroureterectomy was the predominant treatment. Biopsies via a ureteroscope prior to surgery or intraoperative frozen section examination, which yielded the diagnosis of amyloidosis, could help to avoid unnecessary surgery. The use of dimethyl sulfoxide or follow-up with serial imaging may become a promising treatment.

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Bilateral Amyloidosis of the Ureter Associated with Carcinoma

Cited by 13 publications

References 5 publications

Anurea caused by primary amyloidosis of the lower third of the ureters, the ureterovesical junction and the urinary bladder

Anurea caused by primary amyloidosis of the lower third of the ureters, the ureterovesical junction and the urinary bladder

Bilateral localized amyloidosis of the ureters: clinicopathology and therapeutic approaches in two cases

Localized amyloidosis of the ureter: A case report and literature review

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