Benzo[a]pyrene imprinted polymers: synthesis, characterization and SPE application in water and coffee samples

Determination of 16 polycyclic aromatic hydrocarbons in seawater using molecularly imprinted solid-phase extraction coupled with gas chromatography-mass spectrometry

“…Therefore, it is significant and imperative to eliminate the matrix effects for sensitive and accurate determination of PAHs. Excitedly, the binding characteristics of the presented MIPs were still far superior to other MIPs for PAHs reported [23,28,40], and should be sufficient for extracting/removing PAHs present at trace level from natural seawater, as shown 93.2% in Table 3.…”

“…To the best of our knowledge, only several publications have reported PAHs determination based on MIPs by using PAHs as template/analyte. For instances, Benzo[a]pyrene (BaP) was used as a template molecule to synthesize six kinds of MIPs using different functional monomers and cross-linkers for enrichment and separation of BaP from water and coffee samples [23], as well as, pyrene was used as a template molecule to prepare MIPs with molecular recognition properties towards many PAHs [24]. The double molecular imprinting for measurements of PAHs in water was performed with quartz crystal microbalance [25].…”

Molecularly imprinted polymers and their application in solid phase extraction

“…For this purpose, low-polarity organic solvents, such as dichloromethane, toluene, or chloroform, are widely used [21,24]. However, good results have also been obtained with other more polar solvents, such as acetonitrile or methanol [6,25,26]. When water samples are percolated through MIPs, the clean-up step can be problematic because the washing solvent is usually non-polar, which may give rise to miscibility problems, unless the MIP cartridge is dried by purging with air or nitrogen [24,66].…”

Applications of SPE-MIP in the Field of Food Analysis

“…Lai et al prepared 4-VPy, TFMAA, and MAA as functional monomers and DVB or EDMA as cross-linkers in the synthesis of MIPs with a benzo [a]pyrene template. 29 They compared materials synthesized by bulk or precipitation polymerization, where minimal difference in performance was observed in most cases. Not unexpectedly, they found that 4-VPy/DVB bulk co-polymers performed best for their purpose, as a polymer with excess of aromatic groups matches the polycyclic aromatic hydrocarbon structure of benzo[a]pyrene, with the optimal material showing high imprinting factors for the template as well as three closely related compounds.…”