Beneficial effect of low-dose peritonsillar injection of lidocaine–adrenaline before tonsillectomy. A placebo-controlled clinical trial

Does topical lidocaine with adrenaline have an effect on morbidity in pediatric tonsillectomy?

“…Susaman and Kaygusuz [26] suggested that lidocaine HCl aerosol exerted a therapeutic effect on post-operative pain control in tonsillectomy patients. Sorensen et al [27] reported that low-dose injection of lidocaine-adrenaline (3 ml of 1% lidocaine with 1:200,000 adrenaline for each tonsil) before tonsillectomy reduced blood loss and had a small but significant beneficial effect on early post-operative pain.…”

Systematic Review of Clinical Evidence for Local Anesthetic Wound Infiltration in Reduction of Post-Surgical Pain

“…All studies but one used the pre-incisional injection of the tonsillar bed, with six of the studies (out of nine total) finding a reduction in post-operative pain via a pain scale similar to the visual analog scale. [23][24][25][26][27]. Two studies did find that post-operative pain was not reduced [22,28], one stating that after consideration of the usage of other analgesics that they saw no reduction in the amount of the other analgesics required for patient comfort [29].…”

Hemodynamic Changes After Epinephrine (1:200000) Infiltration With or Without Lignocaine in Ent Surgeries

“…Hanuman and Umamaheswara reported more than 20% decrease of MAP in 40 % of the patients compared to the preinfiltration values. (13) Philips and his colleagues noted significant decrease in mean arterial pressure in 55% of the patients. (8) Yang and his colleagues found decrease in mean arterial pressure in 24% of patients when lignocaine was combined with adrenaline.…”

“…Hemostatis can be achieved by vasoconstriction. (11,12,13,14,15,16) Both topically applied and locally infiltrated vasoconstrictor agents reduces bleeding and improve visualization. (11)(12) Adrenaline is a commonly used vasoconstrictor agent, infiltrated locally reduce bleeding and improve visualization.…”