“…Ethylene Oxide Mediated Conversion of Isoquinolines to Isoquinolones and Oxazolidines. Its Extension to Related Nitrogen Heterocycles1 Received -July 14,1978 Treatment of l-(3-methoxy-2-nitrobenzyl)isoquinoline (lb) with ethylene oxide in acetic acid afforded stable 10b-(3-methoxy-2-nitrobenzyl)oxazolo[2,3-a]isoquinoline (3b). Similarly, 1-cyanoisoquinoline (lc) yielded N-(2hydroxyethyl)-1 -isoquinolone (6a) and /V-(2-acetoxyethyl)-l-isoquinolone (6b).…”