Behavioral conditioning and experimental motion-induced sickness

Squirrel Monkeys and Space Motion Sickness

“…The males were more sensitive than the females (latency, 10.50 vs. 24.13 min) with significant individual differences. Regional differences were observed: 59% in Bolivian, 29% in Colombian, but with no significant difference in latency [123,137]. Habituation was observed when the horizontal rotation was repeated [138] A combination of rotatory stimulation with visual stimulation enhanced the incidence of motion sickness (53%, 48.1 min vs. 76%, 17.2 min).…”

“…Habituation was observed when the horizontal rotation was repeated [138] A combination of rotatory stimulation with visual stimulation enhanced the incidence of motion sickness (53%, 48.1 min vs. 76%, 17.2 min). The incidence was higher when the head and body were free to move than when they were restrained [123,137,139]. With a combination of rotation with visual stimulation, the vertical rotation was more effective than the horizontal rotation [140][141][142][143][144][145]; rating scores were 16.4Ϯ1.8 vs. 8.3Ϯ1.77 (cf.…”

“…But when the otolith organ was destructed on only one side, sensitivity recovered 4.4 months after surgery, suggesting that the reorganization occurred in the central nervous system. Motion sickness can be evoked by eccentric rotation [137,139,[147][148][149]. The latencies from the stimulus onset to vomiting formed a Poisson distribution with a median value of 32.25 min (nϭ29; Bolivian), and 91% of the squirrel monkeys vomited in less than 130 min.…”