Beam's-Eye-View Dosimetrics–Guided Inverse Planning for Aperture-Modulated Arc Therapy

Ma, Y.; Popple, Richard A.; Suh, Tae-Suk; Li, Xing

doi:10.1016/j.ijrobp.2009.05.003

Cited by 19 publications

(14 citation statements)

References 26 publications

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“…Recent interest in VMAT as an alternative to IMRT has focused on a variety of sites (3)(4)(5)(6)(7)(8)(9)(10), but studies applied to CNS tumors have been limited to VMAT with coplanar subarcs (11)(12)(13)(14). For VMAT to achieve clinical benefits comparable to IMRT in the treatment of these tumors, multiple and noncoplanar subarcs will likely be needed.…”

Section: Introductionmentioning

confidence: 99%

Choreographing Couch and Collimator in Volumetric Modulated Arc Therapy

Yang¹,

Zhang²,

Happersett³

et al. 2011

International Journal of Radiation Oncology*Biology*Physics

118

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Section: Introductionmentioning

confidence: 99%

Choreographing Couch and Collimator in Volumetric Modulated Arc Therapy

Yang¹,

Zhang²,

Happersett³

et al. 2011

International Journal of Radiation Oncology*Biology*Physics

118

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“…Sweeping window arc therapy (1,2) or volumetric modulated arc therapy (VMAT) (3)(4)(5)(6) is receiving broad interest and gaining research and development momentum. Planning studies from various institutions demonstrate that VMAT plans have similar dosimetric quality but much-reduced treatment delivery time compared with the standard intensity-modulated radiation therapy (IMRT) approach (7)(8)(9)(10)(11).…”

Section: Introductionmentioning

confidence: 99%

Optimization of Collimator Trajectory in Volumetric Modulated Arc Therapy: Development and Evaluation for Paraspinal SBRT

Zhang¹,

Happersett²,

Yang³

et al. 2010

International Journal of Radiation Oncology*Biology*Physics

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“…For each patient, we planned the treatment using Pinnacle TM system (Philips Radiation Oncology Systems, Milpitas, CA), with different numbers of beams (5,7,11,15,23,31,61, and 90 in this study), uniformly distributed in the range of 0 to 360…”

Section: Iia Treatment Planningmentioning

confidence: 99%

“…These techniques include fixedgantry IMRT (Ref. 1) (typically, with five to ten beams) planned using beamlet-based optimization [2][3][4][5] or direct aperture optimization or segment-based optimization, [6][7][8] volumetric modulated arc therapy (VMAT) [9][10][11] (typically with one to two arcs), and Tomotherapy. 12,13 Each of these techniques captures certain aspect(s) of desirable features of radiation therapy (RT) but compromises in either dose distribution (in fixed-gantry IMRT and VMAT) or delivery efficiency (in Tomotherapy TM ).…”

Section: Introductionmentioning

confidence: 99%

Bridging the gap between IMRT and VMAT: Dense angularly sampled and sparse intensity modulated radiation therapy

2011

Medical Physics

Self Cite

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Purpose: To propose an alternative radiation therapy (RT) planning and delivery scheme with optimal angular beam sampling and intrabeam modulation for improved dose distribution while maintaining high delivery efficiency. Methods: In the proposed approach, coined as dense angularly sampled and sparse intensity modulated RT (DASSIM-RT), a large number of beam angles are used to increase the angular sampling, leading to potentially more conformal dose distributions as compared to conventional IMRT. At the same time, intensity modulation of the incident beams is simplified to eliminate the dispensable segments, compensating the increase in delivery time caused by the increased number of beams and facilitating the plan delivery. In a sense, the proposed approach shifts and transforms, in an optimal fashion, some of the beam segments in conventional IMRT to the added beams. For newly available digital accelerators, the DASSIM-RT delivery can be made very efficient by concatenating the beams so that they can be delivered sequentially without operator's intervention. Different from VMAT, the level of intensity modulation in DASSIS-RT is field specific and optimized to meet the need of each beam direction. Three clinical cases (a head and neck (HN) case, a pancreas case, and a lung case) are used to evaluate the proposed RT scheme. DASSIM-RT, VMAT, and conventional IMRT plans are compared quantitatively in terms of the conformality index (CI) and delivery efficiency. Results: Plan quality improves generally with the number and intensity modulation of the incident beams. For a fixed number of beams or fixed level of intensity modulation, the improvement saturates after the intensity modulation or number of beams reaches to a certain level. An interplay between the two variables is observed and the saturation point depends on the values of both variables. For all the cases studied here, the CI of DASSIM-RT with 15 beams and 5 intensity levels (0.90, 0.79, and 0.84 for the HN, pancreas, and lung cases, respectively) is similar with that of conventional IMRT with seven beams and ten intensity levels (0.88, 0.79, and 0.83) and is higher than that of single-arc VMAT (0.75, 0.75, and 0.82). It is also found that the DASSIM-RT plans generally have better sparing of organs-at-risk than IMRT plans. It is estimated that the dose delivery time of DASSIM-RT with 15 beams and 5 intensity levels is about 4.5, 4.4, and 4.2 min for the HN, pancreas, and lung case, respectively, similar to that of IMRT plans with 7 beams and 10 intensity levels. Conclusion: DASSIS-RT bridges the gap between IMRT and VMAT and allows optimal sampling of angular space and intrabeam modulation, thus it provides improved conformity in dose distributions while maintaining high delivery efficiency.

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Beam's-Eye-View Dosimetrics–Guided Inverse Planning for Aperture-Modulated Arc Therapy

Cited by 19 publications

References 26 publications

Choreographing Couch and Collimator in Volumetric Modulated Arc Therapy

Choreographing Couch and Collimator in Volumetric Modulated Arc Therapy

Optimization of Collimator Trajectory in Volumetric Modulated Arc Therapy: Development and Evaluation for Paraspinal SBRT

Bridging the gap between IMRT and VMAT: Dense angularly sampled and sparse intensity modulated radiation therapy

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