Basosquamous Carcinoma

Abstract

In this retrospective study, BSCs displayed tissue invasion similar to that of BCC or SCC but had a higher frequency of pulmonary metastasis than SCC.

BerEp4, Cytokeratin 14, and Cytokeratin 17 Immunohistochemical Staining Aid in Differentiation of Basaloid Squamous Cell Carcinoma From Basal Cell Carcinoma With Squamous Metaplasia

“…The term basosquamous carcinoma has been used by some to describe BCC with squamous metaplasia as well as a prominent stromal proliferation, 17,18 although others apply the same name to collision tumors in which a typical BCC is identified adjacent to SCC. 19 Metatypical BCC has been used synonymously with basosquamous carcinoma by some authors, 6,[18][19] and by others, it is used to describe tumors that have overlapping features of both squamous and basal cell carcinomas, 20 which is how the term is used at our institution. Regardless of the specific nomenclature, there is evidence that BCCm may be more clinically aggressive than classic BCC, [21][22][23][24] citing more aggressive histologic features, such as greater infiltration, more mitoses, increased cytologic atypia, 21 recurrence rates of 10%, 20 and rates of metastases as high as 7.4%, 19 compared with 0.55% for typical BCC.…”

“…19 Metatypical BCC has been used synonymously with basosquamous carcinoma by some authors, 6,[18][19] and by others, it is used to describe tumors that have overlapping features of both squamous and basal cell carcinomas, 20 which is how the term is used at our institution. Regardless of the specific nomenclature, there is evidence that BCCm may be more clinically aggressive than classic BCC, [21][22][23][24] citing more aggressive histologic features, such as greater infiltration, more mitoses, increased cytologic atypia, 21 recurrence rates of 10%, 20 and rates of metastases as high as 7.4%, 19 compared with 0.55% for typical BCC. 20 Only a handful of cutaneous bSCC cases have been reported in the literature, 1,25,26 making it difficult to draw conclusions about the disease's clinical behavior.…”

Pulmonary Metastasectomy in Cutaneous Basosquamous Cell Carcinoma: Case Report

“…BSHK, etraf dokulara invazyon açısından bazal ve skuamöz hücreli kanserlerle benzerlikler gösterirken, hem bazal hem de skuamöz hücreli cilt kanserlerine nazaran daha sık metastaz yapar [4]. Bu da bu iki kanser tipinin bir varyantı olarak kabul edilen BSHK'yı oldukça ilginç kılan bir özelliktir.…”

Evaluation of the Cases Who Were Referred to Plastic Surgery Clinic Out of Suspicion of Non-melanoma Skin Cancer Localized at Head and Neck Region in Sivas Numune Hospital

“…42 En çok baş-boyun bölgesine yerleşim göste-rir. 41,43,44 Birçok patolog bazoskuamöz karsinomu ayrı bir tip olarak kabul etmez ve metatipik karsinom olduğunu savunur. 41 Kutanöz bazoskuamöz karsinomlar bazal hücreli karsinomun histolojik alt tipi olarak kabul edilse de klinik seyir açısından skuamöz hücreli karsinomlar altında sınıflandırı-lır.…”