Basal Cell Epithelioma: A Controlled Study of Associated Factors

Gellin, Gerald A.; Kopf, Alfred W.; Garfinkel, Lawrence

doi:10.1016/b978-0-08-011576-4.50023-4

Cited by 19 publications

(33 citation statements)

References 9 publications

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“…Hogan et al 18 detected no statistical significance for light eye color, whereas Gellin et al 11 did, but using a different type of statistical analysis (chi-square test). In our cases in the present study, similarly to those studied by Hogan et al 18 , light eye color was nonsignificant as a risk factor, with an odds ratio of 1.3.…”

Section: Light Eyesmentioning

confidence: 94%

“…We would like to emphasize four studies in the international literature that will be discussed in detail here: in 1965, Gellin et al 11 carried out a controlled study to determine the factors associated with BCC and showed that there is a statistically significant tendency to the development of BCC in patients with light-colored eyes, with light hair, with light skin, who do not tan, who spend many hours exposed to the sun. However, only 6% of the BCC cases had all of these five characteristics (in contrast to 0.6% of the controls).…”

Section: Discussionmentioning

confidence: 99%

“…However, Gellin et al 11 , in a controlled study of factors associated with BCC, also found no significance for family history of skin cancer. The authors proposed that this may have been due to several factors: 1) the older group of patients may not have remembered details about their parents; 2) different living conditions between patients and ancestors in terms of solar exposure, geographical location, occupation etc.…”

Section: Family History Of Skin Cancermentioning

confidence: 99%

“…However, significance for light hair color as a risk factor has been reported in the international literature 11,15,18 . According to the data of the present study, light hair color was nonsignificant by multiple conditional logistic regression analysis, with an odds ratio of 1.16.…”

Section: Light Hair Colormentioning

confidence: 99%

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Risk factors for basal cell carcinoma: a case-control study

1995

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A controlled trial was performed with the purpose of investigating which factors could be considered of significant risk for the development of basal cell carcinoma. A total of 259 cases of basal cell carcinoma diagnosed from July 1991 to July 1992 were compared with 518 controls matched for age and sex. All subjects in both groups were white. Protocol data were submitted to statistical analysis by the chi-square test and by multiple conditional logistic regression analysis and the following conclusions were reached: 1) light skin color (types I and II of the Fitzpatrick classification), odds ratio of 2.8; outdoor work under constant sunlight, odds ratio of 5.0; the presence of actinic lesions due to exposure to the sun, odds ratio of 4.9, are risk factors perse. 2) Type III skin in the Fitzpatrick classification only represents a risk factor when the patient reports a history of intense sunburns, but not in the absence of such a history. 3) Sunburns per se do not represent a risk factor althorig the point made in item 2 of these conclusions is valid. 4) Other suspected risk factors whose significance was not confirmed by multiple conditioned logistic regression analysis were: residence in rural areas, light eyes and blond hair color, extent of the awareness of the "sun x skin cancer" relationship, familial occurrence of skin cancer, excessive exposure to the sun, and freckles appearing in childhood.Carcinoma, basal cell, epidemiology.Risk factors.

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Section: Light Eyesmentioning

confidence: 94%

Section: Discussionmentioning

confidence: 99%

Section: Family History Of Skin Cancermentioning

confidence: 99%

Section: Light Hair Colormentioning

confidence: 99%

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Risk factors for basal cell carcinoma: a case-control study

1995

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“…Measurement of the effect of sun exposure on NMSC at an individual level has been undertaken in a few studies (Gellin et al, 1965;Urbach et al, 1974;Hunter et al, 1990;Vitasa et al, 1990;GafA et al, 1991). In general, cumulative lifetime sun exposure has a clearer effect on SCC than on BCC (Vitasa et al, 1990;Gafa et al, 1991).…”

mentioning

confidence: 99%