1996
DOI: 10.1038/bjc.1996.275
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The multicentre south European study 'Helios'. II: Different sun exposure patterns in the aetiology of basal cell and squamous cell carcinomas of the skin

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Cited by 370 publications
(329 citation statements)
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References 20 publications
(13 reference statements)
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“…It is also coherent with the fact that LC is rare on the upper lip (de Visser and van der Waal, 1998). The results of the European study Helios (a multicentre case -control study on skin cancer) suggest a differential behaviour of accumulated sun during leisure and work time, depending on the type of skin cancer (leisure exposure for BCC and work exposure for SCC), similar to the findings for melanoma (Armstrong, 1988;Kricker et al, 1995;Rosso et al, 1996).…”
Section: Discussionsupporting
confidence: 75%
“…It is also coherent with the fact that LC is rare on the upper lip (de Visser and van der Waal, 1998). The results of the European study Helios (a multicentre case -control study on skin cancer) suggest a differential behaviour of accumulated sun during leisure and work time, depending on the type of skin cancer (leisure exposure for BCC and work exposure for SCC), similar to the findings for melanoma (Armstrong, 1988;Kricker et al, 1995;Rosso et al, 1996).…”
Section: Discussionsupporting
confidence: 75%
“…Genotoxic damages induced by UV-B radiation (290 -315 nm wavelength) [5][6][7] is linked to the history of multiple sun burns in early ages and intensive intermittent sunlight exposure 8,9 . The incidence of BCC is non-linearly correlated to the total UV exposure with peak at approximately two fold at 10,000-35,000 hours total sun exposure and remaining stable rates with additional exposure 10,11 .…”
Section: Aetiological Risk Factors and Pathobiologymentioning
confidence: 99%
“…Chronic exposure, including from sunbeds, 16 is mainly implicated, 17 with acute exposure thought to be less important. 18 Human papillomavirus is a suspected risk factor 19 although the evidence is not as strong as for other sites such as the cervix and oropharynx. Increased age, male gender and Caucasian ethnicity are associated with increased risk, as are irradiation and exposure to chemicals such as arsenic and polycyclic aromatic hydrocarbons.…”
Section: Squamous Cell Carcinoma Epidemiologymentioning
confidence: 99%