Basal cell carcinoma with intracranial invasion

Kleydman, Yekaterina; Manolidis, Spiros; Ratner, Désirée

doi:10.1016/j.jaad.2008.10.005

Cited by 23 publications

(19 citation statements)

References 22 publications

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“…Kleydman et al reported a case in which a basal cell carcinoma of the left nasal ala retrogradely invaded the orbit, including the SOF and much of the skull base. Because most of the involvement was around the orbit, the patient experienced bilateral vision loss, tearing, and swelling [25]. Squamous cell carcinomas have also been reported [26].…”

Section: Reviewmentioning

confidence: 99%

Cranial Nerve Foramina Part I: A Review of the Anatomy and Pathology of Cranial Nerve Foramina of the Anterior and Middle Fossa

Edwards¹,

Wang²,

Iwanaga³

et al. 2018

Cureus

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Cranial nerve foramina are integral exits from the confines of the skull. Despite their significance in cranial nerve pathologies, there has been no comprehensive anatomical review of these structures. Owing to the extensive nature of this topic, Part I of our review, presented here, focuses on the foramina of the anterior and middle cranial fossae, discussing each foramen’s shape, orientation, size, surrounding structures, and structures that traverse them. Furthermore, by comparing the size of each foramen against the cross-sectional areas of its contents, we estimate the amount of free space in each. We also review lesions that can obstruct the foramina and discuss their clinical consequences.

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Section: Reviewmentioning

confidence: 99%

Cranial Nerve Foramina Part I: A Review of the Anatomy and Pathology of Cranial Nerve Foramina of the Anterior and Middle Fossa

Edwards¹,

Wang²,

Iwanaga³

et al. 2018

Cureus

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“…If the lesion is not treated in its earlier stages it can lead to destruction of underlying tissue, including intracranial invasion. 47 Although the cancer is not known to be associated with a high mortality, there have been a few cases of metastasis to the central nervous system and the bone. 48 These cases are extremely rare, and it is much more common for basal cell carcinomas to be locally aggressive than systemically involved.…”

Section: Basal Cell Carcinomamentioning

confidence: 99%

Malignant Skin Neoplasms

Ricotti

Bouzari

Agadi³

et al. 2009

Medical Clinics of North America

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Skin cancer is the most common form of cancer in the United States, with the incidence increasing considerably. At current rates in the United States, a skin cancer will develop in 1 in 6 people during their lifetime.1 The most common of skin cancers may be categorized into 2 major groups: melanoma and nonmelanoma skin cancers. The latter group consists primarily of basal cell carcinomas and squamous cell carcinomas. Roughly 1,200,000 nonmelanoma skin cancers develop annually in the United States. These tumors are rarely fatal, but are considered to be fast growing tumors that if neglected may be locally and functionally destructive.In contrast, melanoma represents 5% of all diagnosed cancers in the United States, 15% of which prove to be fatal.3 Although melanoma is seen more with increasing age, it is the most frequent cancer plaguing women aged 25 to 29 years, and the second most frequent cancer afflicting women aged 30 to 34.2 Tumor depth is the most important prognostic indicator for melanoma, thus early recognition and management are imperative for improved therapeutic outcome.Although the nonmelanoma and melanoma skin cancers encompass the vast majority of skin cancers, there is a large number of other malignancies of the skin that are less commonly confronted by the clinician. Neoplasms of the skin classically have been divided into those that differentiate from the epidermis, dermis, adnexal structures of the skin, and those derived systemically. This review focuses on the most frequent malignant neoplasms, and divides them into those that are classically designated nonmelanoma skin cancers (also known as keratinocytic tumors), melanoma, and other less common skin cancers of the skin. An extensive list of skin malignancies is provided in Box 1.

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“…In the literature few case reports are reported, particularly with invasion of supratentorial structures (2,4). After review of the literature this is the first case report describing such an intracranial infiltration of BCC with this localization and extension.…”

Section: Discussionmentioning

confidence: 81%

“…BCC of the head and neck are the most common, (1,3,5) particularly on the face and scalp due to the sun exposure and thus ultraviolet radiation, which is considered to be the main cause of developing BCC. Intracranial invasion is very rare and has been reported only in a few cases (2,4). All these case reports describe intracranial infiltration of structures with supratentorial localization.…”

Section: Introductionmentioning

confidence: 99%

Intracranial basal cell carcinoma with extensive invasion of the skull base

Mahvash

2014

Turkish Neurosurgery

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Intracranial invasion of basal cell carcinoma is very rare. A case of a 71-year-old male patient is presented with extensive invasion of middle and posterior fossae, with nearly complete destruction of the petrous bone, involving cerebellopontine angle and cranial nerves by recurrent basal cell carcinoma of the auricular region on the right side. The clinical manifestation was cerebrospinal fluid otorrhoea, facial nerve palsy and trigeminal nerve impairment with hypoesthesia. The patient underwent surgery by combined retroauricular and temporal approach to the skull base. Adjuvant radiation of residual tumor and former tumor recurrence region was performed. MRI studies performed annually show no progress of the tumor. Our patient reports a good quality of life without new neurological deficits 6 years after surgery. Attention should be paid to the malignant nature of basal cell carcinoma making follow up care necessary. In indicated cases in which incomplete excision cannot be excepted and risk factors exist, follow up with CT or/and MRI should be performed to evaluate the infiltrative and invasive character of aggressive basal cell carcinoma and to rule out bone or cerebral infiltration. KEywORDS: Basal cell carcinoma, Intracranial invasion, Skull base ÖZBazal hücreli karsinomun intrakraniyal invazyonu çok nadirdir. Orta ve posterior fossada belirgin invazyon, petröz kemiğin hemen hemen tümüyle harabiyeti, serebellopontin açı ve kraniyal sinirlerin sağ tarafta auriküler bölgede nüks bazal hücreli karsinom tarafından tutulduğu 71 yaşında bir erkek olguyu sunuyoruz. Klinik bulgular serebrospinal sıvı otoresi, fasiyal sinir palsisi ve hipoesteziyle birlikte trigeminal sinir tutulumu şeklindeydi. Hastada kafa kaidesine kombine retroauriküler ve temporal yaklaşımla cerrahi yapıldı. Kalan tümör ve daha önceki tümör nüks bölgesine adjuvan radyasyon uygulandı. Yılda bir yapılan MRG çalışmaları tümörde ilerleme göstermedi. Hastamız cerrahiden 6 yıl sonra yeni bir nörolojik defisit olmadan iyi bir yaşam kalitesi bildirmektedir. Bazal hücreli karsinomun malign özelliğine dikkat edilmelidir ve takip gereklidir. Tam olmayan eksizyonun kabul edilemeyeceği ve risk faktörlerinin bulunduğu, endike olan olgularda agresif bazal hücreli karsinomun infiltratif ve invaziv karakterini değerlendirmek ve kemik veya serebral infiltrasyonu ekarte etmek açısından BT ve/veya MRG ile takip yapılmalıdır. ANAHTAR SÖZCÜKLER:Bazal hücreli karsinom, İntrakraniyal invazyon, Kafa kaidesi

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Basal cell carcinoma with intracranial invasion

Cited by 23 publications

References 22 publications

Cranial Nerve Foramina Part I: A Review of the Anatomy and Pathology of Cranial Nerve Foramina of the Anterior and Middle Fossa

Cranial Nerve Foramina Part I: A Review of the Anatomy and Pathology of Cranial Nerve Foramina of the Anterior and Middle Fossa

Malignant Skin Neoplasms

Intracranial basal cell carcinoma with extensive invasion of the skull base

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