Bar, Soft and Dri Post-Hepatic Transplantation: What Is the Best for Survival Analysis?

Abstract

Background: Liver transplantation is the treatment of choice for patients with terminal liver disease. The Balance of Risk Score (BAR), Survival Outcomes Following Liver Transplantation (SOFT) and Donor Risk Index (DRI) scores are predictive systems for post-transplant survival. Aim: To evaluate the most accurate score and the best cutoff point for each predictor in the brazilian population. Method: Retrospective cross-sectional study of 177 patients. Data on the recipient, donor and transplant were analyzed and the prognostic scores BAR, SOFT and DRI were calculated for each transplant. To determine the BAR and SOFT cutoff points associated with death in three months, ROC curves were adjusted. Results: The best cutoff point for BAR was 9 points with an area under the ROC curve=0.69 and for SOFT it was 12 points with an area under the ROC curve=0.73. The DRI score did not discriminate survival (p = 0.139). Conclusion: The SOFT score proved to be better than BAR for survival analysis post-hepatic transplantation and the DRI was not effective.

Combined Heart-Liver-Kidney Transplantation: The First Experience in Latin America

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“…Hepatic and renal dysfunction may be secondary to a systemic disease process affecting the heart, liver, and kidneys or may be a consequence of heart failure with venous congestion and arterial hypoperfusion 2 , 4 .…”

Risk factors in deceased donor liver transplantation: a single centre experience

“…Связь донорского креатинина с результатами трансплантации печени нашла свое отражение, в частности, в прогностической шкале SOFT [22]. Однако механизм этого влияния достоверно не установлен.…”

Drogas Imunossupressoras Afetam Os Núcleos Hipotalâmicos Envolvidos Na Ingestão Alimentar ? Estudo Experimental

“…No entanto, o aumento da sobrevida dos pacientes submetidos ao transplante hepático foi acompanhado por um aumento na prevalência de doenças crônicas, geralmente superior à prevalência encontrada na população em geral. Além disso, destaca-se o ganho de peso vivenciado por esses pacientes, gerando sobrepeso e obesidade com impacto na sobrevida 25 .…”

“…However, the increased patients’ survival undergoing liver transplantation was accompanied by an increase in the prevalence of chronic diseases, generally higher than the prevalence found in the general population. In addition, the weight gain experienced by these patients stands out, generating overweight and obesity with impact on survival 25 .…”