Banxia Xiexin tang for gastro-oesophageal reflux disease

Kang, Bohyung; Lee, Haesol; Choi, You-kyung; Jeon, Chan‐Yong; Lee, Ju Ah

doi:10.1097/md.0000000000010393

Cited by 2 publications

(1 citation statement)

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“…A systematic review of controlled trials, including randomized controlled trials (RCTs) of BXD as a treatment for GERD, in eleven databases, revealed the effectiveness and safety of BXD for the treatment of GERD. [83] Another meta-analysis based on previous systematic reviews/meta-analyses further provided evidence that BXD had promising efficacy to treat GERD patients. [88] In treatment of 40 cases of laryngopahryngitis caused by GERD, it has been found in a parallel study that the therapeutic effect of modified BXD is significantly more effective than Jinsang Liyan Wan (Pills for a good voice by relieving www.md-journal.com sore-throat).…”

Section: Application Of Bxd In Treatment Of Gerdmentioning

confidence: 99%

Banxia Xiexin decoction: A review on phytochemical, pharmacological, clinical and pharmacokinetic investigations

Zhou,

An,

You

et al. 2023

Medicine

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Banxia Xiexin decoction (BXD), a famous traditional Chinese prescription constituted by Pinelliae Rhizoma, Zingiberis Rhizoma, Scutellariae Radix, Coptidis Rhizoma, Ginseng Radix et Rhizoma, Jujubae Fructus and Glycyrrhizae Radix et Rhizoma Praeparata Cum Mell, has notable characteristics of acrid-opening, bitter down-bearing and sweet-tonification, interfering with tumors, gastrointestinal diseases, central nervous system diseases and much more. Based on the wide clinical applications, current investigations of BXD focused on several aspects: chemical analysis to explore the underlying substrates responsible for the therapeutic effects; basic studies on pharmacological actions of the whole prescription or of those representative ingredients to demonstrate the intriguing molecular targets for specific pathological processes; pharmacokinetic feature studies of single or all components of BXD to reveal the chemical basis and synergistic actions contributing to the pharmacological and clinically therapeutic effects. In this review, we summarized the main achievements of phytochemical, pharmacological, clinical and pharmacokinetic profiles of BXD and its herbal or pharmacologically active chemicals, as well as discussions of our understanding which further reveals the significance of BXD clinically.

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Section: Application Of Bxd In Treatment Of Gerdmentioning

confidence: 99%