Balance Capabilities after Lateral Ankle Trauma and Intervention

Wikstrom, Erik A.; Naik, Sagar K.; Lodha, Neha; Cauraugh, James H.

doi:10.1249/mss.0b013e318196cbc6

Cited by 129 publications

(105 citation statements)

References 64 publications

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“…Sensitivity analysis was performed to evaluate whether the removal of a single study would influence the overall outcomes. The funnel plot, classic fail-safe N, and Egger linear regression tests were adopted to assess publication bias to ensure the reliability of the results (Egger et al, 1997;Sterne and Egger, 2001;Wikstrom et al, 2009). A bilateral test was conducted with P < 0.05 indicating significance.…”

Section: Discussionmentioning

confidence: 99%

Association between TNF-αrs1799724 and rs1800629 polymorphisms and the risk of Crohn’s disease

Yq¹,

Sq²,

Gao³

2015

Genet. Mol. Res.

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ABSTRACT. We investigated the associations between 2 major tumor necrosis factor-α (TNF-α) polymorphisms, rs1799724 C>T and rs1800629 G>A, and the susceptibility to Crohn's disease (CD) using a metaanalysis framework. The PubMed, EBSCO, Ovid, Wiley, Web of Science, WANFANG, and VIP databases (last updated search in October 2014) were comprehensively searched for relevant published studies. The studies retrieved from database searches were filtered based on inclusion and exclusion criteria, and the resultant data extracted from the selected studies were analyzed using the Comprehensive Meta-analysis 2.0 software. Eleven case-control studies, containing 2000 CD patients and 3499 healthy controls, were identified as relevant to this meta-analysis. Data extracted from these 11 studies were analyzed to understand the role of the 2 TNF-α polymorphisms in CD. We found that the TNF-α rs1799724 C>T (2015) polymorphism increased the susceptibility to CD (allele model: OR = 1.293, 95%CI = 1.090-1.534, P = 0.003; dominant model: OR = 1.258, 95%CI = 1.031-1.534, P = 0.024). In contrast, we found no significant association between the TNF-α rs1800629 G>A polymorphism and CD susceptibility (allele model: OR = 1.005, 95%CI = 0.864-1.170, P = 0.945; dominant model: OR = 0.962, 95%CI = 0.809-1.145, P = 0.667). This meta-analysis showed that the TNF-α rs1799724 C>T polymorphism is associated with CD susceptibility, while the TNF-α rs1800629 G>A polymorphism appeared to have no correlation with the susceptibility to CD.

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Section: Discussionmentioning

confidence: 99%

Association between TNF-αrs1799724 and rs1800629 polymorphisms and the risk of Crohn’s disease

Yq¹,

Sq²,

Gao³

2015

Genet. Mol. Res.

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“…Sensitivity analysis was conducted to estimate the effects of a single study on the overall results. Publication bias was evaluated by classic fail-safe N, funnel plots and Egger's test (26)(27)(28). All statistical analyses were performed using Comprehensive Meta-Analysis software version 2.0 (Biostat, Inc., Englewood, NJ, USA).…”

Section: Discussionmentioning

confidence: 99%

Elevated matrix metalloproteinase-9 expression may contribute to the pathogenesis of bladder cancer

Zeng

Cen²,

Kang³

2016

Oncology Letters

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Abstract. The present study investigated the potential association between matrix metalloproteinase-9 (MMP-9) expression and the pathogenesis of bladder cancer. The present study reviewed previous studies published in Chinese and English using predefined selection criteria, which identified high-quality studies concerning MMP-9 and bladder cancer. Statistical analyses of the data were conducted using Comprehensive Meta-Analysis software version 2.0. In total, 23 case-control studies were selected, which consisted of 1,040 bladder cancer patients and 244 healthy controls. The expression rates and protein levels of MMP-9 were significantly increased in bladder cancer patients compared with the healthy controls, which was demonstrated using immunohistochemistry (IHC) and enzyme-linked immunosorbent assay-based methods. Furthermore, the expression rate of MMP-9 in histological G1/G2 grade bladder cancer tumors was significantly decreased compared with G3 tumors. Subgroup analysis based on ethnicity demonstrated that the rate of MMP-9 protein expression between bladder cancer patients and healthy controls was significantly different in African, Asian and Caucasian patients, which was identified using IHC. The MMP-9 protein levels in bladder cancer patients and healthy controls were significantly different between Asian and Caucasian patients, but not African patients. The differences between MMP-9 expression in ethnic groups were also evident in the expression rate of MMP-9 identified in histological G1/G2 grade tumors in Asian and Caucasian patients compared with G3 grade tumors, which was not evident in African patients. In conclusion, the present meta-analysis results markedly indicate that MMP-9 expression is associated with clinicopathological features of bladder cancer, suggesting that MMP-9 may be a useful biomarker in the diagnosis and clinical management of bladder cancer, and may be a valuable therapeutic target. IntroductionWorldwide, bladder cancer is the 7th most common cancer in men and the 17th most common cancer in women (1). Notably, in the developed world, bladder cancer ranks as the 4th and 9th most common cancer in men and women, respectively (2). An estimated 375,000 bladder cancer cases are reported each year around the world, with 68,810 novel cases and ~14,100 mortalities reported in the United States in 2013 (3). Transitional cell carcinoma is the most frequently occurring type of bladder cancer. Other bladder cancer types consist of adenocarcinoma, squamous cell carcinoma and small cell bladder cancer (4,5). Notably, the incidence of bladder cancer increases with age, particularly in men (6). Bladder cancer arises as a result of multistep alterations, among which metastasis is crucial (7). Epidemiological studies have demonstrated that several environmental factors may contribute to bladder cancer risk, including smoking, chronic inflammation, radiation exposure, anticancer drugs and aromatic amines, which are contained in dyes (6,8). The treatment of bladder cancer is based on multiple para...

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“…One-way sensitivity analysis was carried out to evaluate whether the removal of a single study would influence the overall outcome. Publication bias, an assessment of the reliability of the results, was evaluated by funnel plot, Egger test (Egger et al, 1997;Sterne et al, 2001), and classic fail-safe N (Wikstrom et al, 2009). All tests were two-sided, with P < 0.05 indicating a significant difference.…”

Section: Methodsmentioning

confidence: 99%

APOA5 -1131T>C and APOC3 -455T>C polymorphisms are associated with an increased risk of coronary heart disease

2015

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ABSTRACT. The aim of this study was to investigate correlations between apolipoprotein A-V (APOA5) -1131T>C and apolipoprotein C-III (APOC3) -455T>C polymorphisms and coronary heart disease (CHD). PubMed, Ovid, Cochrane Library, Embase, China National Knowledge Infrastructure, and Wanfang databases were searched using combinations of keywords relating to these polymorphisms and CHD. Studies retrieved from database searches were screened using our stringent inclusion and exclusion criteria, and Comprehensive Meta-Analysis Version 2.0 software was used for statistical analyses. In total, 115 studies were initially retrieved and after further selection, 11 were included in the metaanalysis. These 11 articles comprised 4840 patients with CHD in the case group and 4913 healthy participants in the control group. Meta-analysis revealed that APOA5 -1131T>C and APOC3 -455T>C polymorphisms increased CHD risk. In addition, subgroup analysis by ethnicity showed that while the -1131T>C polymorphism elevated the risk of CHD in the Caucasian population under both allelic and dominant models, this increased risk was observed only under a dominant model in the Asian 18219 APOA5 and APOC3 polymorphisms and coronary heart disease ©FUNPEC-RP www.funpecrp.com.br Genetics and Molecular Research 14 (4): 18218-18228 (2015) population. The results of our meta-analysis point to a strong link between both APOA5 -1131T>C and APOC3 -455T>C polymorphisms and an increased risk of CHD. Thus, these polymorphisms constitute important predictive indicators of CHD susceptibility.

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Balance Capabilities after Lateral Ankle Trauma and Intervention

Cited by 129 publications

References 64 publications

Association between TNF-αrs1799724 and rs1800629 polymorphisms and the risk of Crohn’s disease

Association between TNF-αrs1799724 and rs1800629 polymorphisms and the risk of Crohn’s disease

Elevated matrix metalloproteinase-9 expression may contribute to the pathogenesis of bladder cancer

APOA5 -1131T>C and APOC3 -455T>C polymorphisms are associated with an increased risk of coronary heart disease

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