Bacterial killing efficacy of synthesized rod shaped cuprous oxide nanoparticles using laser ablation technique

Abstract

Recent interests with copper nanoparticles (Cu-NPs) has arisen because of its low cost and antibacterial properties, as it may be one of the very important alternatives to silver NPs. Pulsed laser ablation of a solid target (copper) in liquid media is used to synthesize colloidal oxide copper (Cu 2 O and CuO NPs) NPs. These oxides of copper NPs were synthesized using Nd:YAG laser energy to maintain a 40 mJ/pulse wavelength at 1064 nm. During the synthesis of colloidal NPs only two conditions were opted, employing double distilled water (without PEG) and 10% preparation of PEG. Both NPs were prepared under the similar parameters such as optimized instrument settings, laser energy and time of laser exposure (1 h ablation). Further, these copper oxide NPs were characterized by advance technologies including UV-visible, X-ray diffraction, transmission electron microscopy and attenuated total reflection Fourier transform infrared spectroscopy techniques. The significant antibacterial properties of synthesized materials were also observed. The cuprous oxide NPs, showed remarkable antibacterial effect conducted using disc diffusion techniques. The minimum inhibitory concentration and minimum bactericidal concentration of synthesized Cu 2 O NPs were recorded as 120 and 140 μg/L respectively against Staphylococcus aureus used as positive control. Therefore, based on the findings of present study Cu 2 O NPs can be exploited as stable antimicrobial agents for multipurpose uses.

Green Synthesis and Characterization of Silver NPs Using Oyster Mushroom Extract For Antibacterial Efficacy

“…Since historic time silver is well known for antimicrobial noble and coinage metal and is being deliberately used to store potable water of daily use to improve silver content. In recent decade silver NPs shown its significance of antimicrobial and antifungal nature compared to its bulk counterpart because of increased surface to volume ratio (Davies & Etris, 1997;Bhardwaj et al, 2019b). Silver NPs got popularity in the incorporation of a diverse range of commercial products, including plastics, soaps, pastes, food and textiles, increasing their market value due to broad spectrum bactericidal and fungicidal activity (Ahamed et al, 2010;Bhardwaj et al, 2019a).…”

Plant mediated synthesis of flower-like Cu2O microbeads from Artimisia campestris L. extract for the catalyzed synthesis of 1,4-disubstituted 1,2,3-triazole derivatives

“…This distinction is supported by previous studies, which note that Cu 2 O and CuO phases exhibit unique absorption patterns in the UV-Vis spectrum due to differences in their electronic structures and bandgap energies. Specifically, CuO is characterized by a distinct absorption peak at around 640 nm, while Cu 2 O displays a primary absorption peak within the 200–270 nm range, corresponding to a red shift in the visible spectrum ( Bhardwaj et al, 2019 ). The bandgap of Cu 2 O microbeads is typically around 2.7 eV ( Figure 4B ), which places it in the category of a direct bandgap semiconductor ( Srinivasan et al, 2021 ).…”

Cyanobacteria as biochemical energy source for the synthesis of inorganic nanoparticles, mechanism and potential applications: a review

“…The laser ablation and evaporation condensations of the physical method of synthesis are the most preferably used. However, they have several drawbacks such as expensive production, lower yields, energy consuming and time-consuming synthesis (Bhardwaj et al 2019b;Singh et al 2010). Similarly, the direct involvement of noxious chemicals during chemical synthesis of nanomaterials is damaging to the environment and living creatures, which can never be part of the eco-friendly policy.…”