Autologous amnion graft for repair of myelomeningocele: technical note and clinical implication

Hasegawa, Mitsuhiro; Fujisawa, Hironori; Hayashi, Yutaka; Yamashita, Junkoh

doi:10.1016/j.jocn.2003.11.006

Cited by 37 publications

(18 citation statements)

References 24 publications

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“…For example, it has long been suggested that nonpreserved human AM transplantation in patients with acute chemical eye burns may reduce surface inflammation, increase patient comfort and decrease the extent and severity of vascularization [144]. Additionally, an autograft of amniotic tissue can be used as an autologous grafting material in a variety of pediatric neurosurgical procedures, such as for repair of myelomeningocele, with no risks of rejection, foreign-body reactions or transmission of slow virus infection [145]. For covering venous ulcers that do not respond to conventional treatment, human AM demonstrates excellent therapeutic potential for re-epithelialization but is less expensive than other skin substitutes [146].…”

Section: Tissue Grafts Of Human Originmentioning

confidence: 99%

Advancing biomaterials of human origin for tissue engineering

Chen

Liu

2016

Progress in Polymer Science

925

513

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Biomaterials have played an increasingly prominent role in the success of biomedical devices and in the development of tissue engineering, which seeks to unlock the regenerative potential innate to human tissues/organs in a state of deterioration and to restore or reestablish normal bodily function. Advances in our understanding of regenerative biomaterials and their roles in new tissue formation can potentially open a new frontier in the fast-growing field of regenerative medicine. Taking inspiration from the role and multi-component construction of native extracellular matrices (ECMs) for cell accommodation, the synthetic biomaterials produced today routinely incorporate biologically active components to define an artificial in vivo milieu with complex and dynamic interactions that foster and regulate stem cells, similar to the events occurring in a natural cellular microenvironment. The range and degree of biomaterial sophistication have also dramatically increased as more knowledge has accumulated through materials science, matrix biology and tissue engineering. However, achieving clinical translation and commercial success requires regenerative biomaterials to be not only efficacious and safe but also cost-effective and convenient for use and production. Utilizing biomaterials of human origin as building blocks for therapeutic purposes has provided a facilitated approach that closely mimics the critical aspects of natural tissue with regard to its physical and chemical properties for the orchestration of wound healing and tissue regeneration. In addition to directly using tissue transfers and transplants for repair, new applications of human-derived biomaterials are now focusing on the use of naturally occurring biomacromolecules, decellularized ECM scaffolds and autologous preparations rich in growth factors/non-expanded stem cells to either target acceleration/magnification of the body's own repair capacity or use nature's paradigms to create new tissues for restoration. In particular, there is increasing interest in separating ECMs into simplified functional domains and/or biopolymeric assemblies so that these components/constituents can be discretely exploited and manipulated for the production of bioscaffolds and new biomimetic biomaterials. Here, following an overview of tissue auto-/allo-transplantation, we discuss the recent trends and advances as well as the challenges and future directions in the evolution and application of human-derived biomaterials for reconstructive surgery and tissue engineering. In particular, we focus on an exploration of the structural, mechanical, biochemical and biological information present in native human tissue for bioengineering applications and to provide inspiration for the design of future biomaterials.

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Section: Tissue Grafts Of Human Originmentioning

confidence: 99%

Advancing biomaterials of human origin for tissue engineering

Chen

Liu

2016

Progress in Polymer Science

925

513

View full text Add to dashboard Cite

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“…Human Amniotic Membrane (AM) allograft has been used in ophthalmology, surgical dressings, vestibuloplasty and even in pediatric neurosurgical procedure like myelomeningocele and dura mater repair for quite a while [12][13][14][15][16][17][18][19]. Recently, human amniotic membrane has been applied successfully in one report on the reconstruction of long ureteral strictures in human [20].…”

Section: Introductionmentioning

confidence: 99%

“…Amniotic membrane graft owes its predominance to some of its own unique characteristics, mainly ''re-eplithelization'', besides the fact that amniotic cells do not cause an immunologic response, and also do not form scars [17][18][19]. Furthermore, the graft is resistant to rejection and can be left in place if infection occurs [20].…”

Section: Introductionmentioning

confidence: 99%

Application of amniotic membrane as xenograft for urethroplasty in rabbit

et al. 2009

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“…Fontenla et al 2 and del Campo et al 4 , report that in 1995, Kim and Tseng reintroduced the use of amniotic membrane in the treatment of ocular lesions, ophthalmology being the specialty where more research is made on the use of amniotic membrane today. There are other studies on its use for burns 5,6 , varicose ulcers 5,7 , neovagina reconstruction 5,8 , urinary bladder 5,9 , nerve damage 5,10 , mouth sores 5,11 , adhesions control and early healing of peritoneal lesions 5,12 , among others. The study of clinical use of amniotic membrane is of increasing importance due to its low antigenicity, antimicrobial activity, ability to decrease exudate and adhesions, to accelerate epithelization, reducing the local pain, actingas a substrate for tissue growth, among many other actions 5 .…”

Section: Introduction Introduction Introduction Introduction Introducmentioning

confidence: 99%

Use of the amniotic membrane to cover the peritoneal cavity in the reconstruction of the abdominal wall with polypropylene mesh in rats

Barbuto

Araújo

Bonomi³

et al. 2015

Rev. Col. Bras. Cir.

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Use of the amniotic membrane to cover the peritoneal cavity in the reconstruction of the abdominal wall with polypropylene mesh in rats Use of the amniotic membrane to cover the peritoneal cavity in Use of the amniotic membrane to cover the peritoneal cavity in Use of the amniotic membrane to cover the peritoneal cavity in Use of the amniotic membrane to cover the peritoneal cavity in Use of the amniotic membrane to cover the peritoneal cavity in the reconstruction of the abdominal wall with polypropylene the reconstruction of the abdominal wall with polypropylene the reconstruction of the abdominal wall with polypropylene the reconstruction of the abdominal wall with polypropylene the reconstruction of the abdominal wall with polypropylene mesh in rats mesh in rats mesh in rats mesh in rats mesh in rats Uso da membrana amniótica como cobertura da cavidade abdominal na Uso da membrana amniótica como cobertura da cavidade abdominal na Uso da membrana amniótica como cobertura da cavidade abdominal na Uso da membrana amniótica como cobertura da cavidade abdominal na Uso da membrana amniótica como cobertura da cavidade abdominal na reconstrução da parede com tela de polipropileno em ratos reconstrução da parede com tela de polipropileno em ratos reconstrução da parede com tela de polipropileno em ratos reconstrução da parede com tela de polipropileno em ratos reconstrução da parede com tela de polipropileno em ratos Objective Objective: to evaluate the efficacy of the amniotic membrane used with polypropylene mesh against the formation of adhesions and its influence on healing. Methods Methods Methods Methods Methods: twenty five female Wistar rats were anesthetized for creating a parietal defect in the anterior abdominal wall. Its correction was made with polypropylene mesh alone and associated with amniotic membrane. In the control group (n=11), the screen was inserted alone. In group A (n=7) we interposed the amniotic membrane between the screen and the abdominal wall. In group B, the amniotic membrane was placed on the mesh, covering it. After seven days, the animals were euthanized for macroscopic and microscopic evaluation of healing. Results Results ResultsResults Results: adhesions were observed in all animals except one in the control group. Severe inflammation was observed in all animals in groups A and B and in three of the control group, with significant difference between them (A and B with p=0.01). Pronounced angiogenic activity was noted in one animal in the control group, six in group A and four in group B, with a significant difference between the control group and group A (p=0.002) and group B (p=0.05). The scar collagen was predominantly mature, except in five animals of the control group, with significant difference between the control group and group A (p=0.05) and group B (p=0.05). Conclusion Conclusion Conclusion Conclusion Conclusion: The amniotic membrane did not alter the formation of adhesions in the first postoperative week. There were also pronounced inflammation, high angiogenic activit...

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Autologous amnion graft for repair of myelomeningocele: technical note and clinical implication

Cited by 37 publications

References 24 publications

Advancing biomaterials of human origin for tissue engineering

Advancing biomaterials of human origin for tissue engineering

Application of amniotic membrane as xenograft for urethroplasty in rabbit

Use of the amniotic membrane to cover the peritoneal cavity in the reconstruction of the abdominal wall with polypropylene mesh in rats

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