Use of the amniotic membrane to cover the peritoneal cavity in the reconstruction of the abdominal wall with polypropylene mesh in rats Use of the amniotic membrane to cover the peritoneal cavity in Use of the amniotic membrane to cover the peritoneal cavity in Use of the amniotic membrane to cover the peritoneal cavity in Use of the amniotic membrane to cover the peritoneal cavity in Use of the amniotic membrane to cover the peritoneal cavity in the reconstruction of the abdominal wall with polypropylene the reconstruction of the abdominal wall with polypropylene the reconstruction of the abdominal wall with polypropylene the reconstruction of the abdominal wall with polypropylene the reconstruction of the abdominal wall with polypropylene mesh in rats mesh in rats mesh in rats mesh in rats mesh in rats Uso da membrana amniótica como cobertura da cavidade abdominal na Uso da membrana amniótica como cobertura da cavidade abdominal na Uso da membrana amniótica como cobertura da cavidade abdominal na Uso da membrana amniótica como cobertura da cavidade abdominal na Uso da membrana amniótica como cobertura da cavidade abdominal na reconstrução da parede com tela de polipropileno em ratos reconstrução da parede com tela de polipropileno em ratos reconstrução da parede com tela de polipropileno em ratos reconstrução da parede com tela de polipropileno em ratos reconstrução da parede com tela de polipropileno em ratos Objective Objective: to evaluate the efficacy of the amniotic membrane used with polypropylene mesh against the formation of adhesions and its influence on healing. Methods Methods Methods Methods Methods: twenty five female Wistar rats were anesthetized for creating a parietal defect in the anterior abdominal wall. Its correction was made with polypropylene mesh alone and associated with amniotic membrane. In the control group (n=11), the screen was inserted alone. In group A (n=7) we interposed the amniotic membrane between the screen and the abdominal wall. In group B, the amniotic membrane was placed on the mesh, covering it. After seven days, the animals were euthanized for macroscopic and microscopic evaluation of healing. Results Results ResultsResults Results: adhesions were observed in all animals except one in the control group. Severe inflammation was observed in all animals in groups A and B and in three of the control group, with significant difference between them (A and B with p=0.01). Pronounced angiogenic activity was noted in one animal in the control group, six in group A and four in group B, with a significant difference between the control group and group A (p=0.002) and group B (p=0.05). The scar collagen was predominantly mature, except in five animals of the control group, with significant difference between the control group and group A (p=0.05) and group B (p=0.05). Conclusion Conclusion Conclusion Conclusion Conclusion: The amniotic membrane did not alter the formation of adhesions in the first postoperative week. There were also pronounced inflammation, high angiogenic activit...
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.