Auditory neuropathy spectrum disorder: Its prevalence and audiological characteristics in an Indian tertiary care hospital

Mittal, Rajan; Ramesh, AV; Panwar, SS; Nilkanthan, Ajith; Nair, Satish; Mehra, Poonam Raj

doi:10.1016/j.ijporl.2012.06.005

Cited by 29 publications

(22 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…ANSD was diagnosed in 5% of the cases which compares to previous reports where the prevalence of ANSD in children ranged from 4.1 to 14% [40,55,56]. For developing countries such as India and Egypt, the reported prevalence ranges are 13.4 to 14% [57,58] and reports available for sub-Saharan Africa suggest an even higher prevalence. In Nigeria the reported prevalence ranges between 10.3 to 15.9% [32] and in South Africa an even higher prevalence of 21.4% was recently reported [24].…”

Section: Discussionmentioning

confidence: 57%

Profound childhood hearing loss in a South Africa cohort: Risk profile, diagnosis and age of intervention

Roux

Swanepoel

Louw

et al. 2015

International Journal of Pediatric Otorhinolaryngology

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 57%

Profound childhood hearing loss in a South Africa cohort: Risk profile, diagnosis and age of intervention

Roux

Swanepoel

Louw

et al. 2015

International Journal of Pediatric Otorhinolaryngology

View full text Add to dashboard Cite

“…Previous reports have indicated prevalence for ANSD of between 5 to 17% of SNHL in children [16,17,18,19]. This prevalence has shown to increase when only severe to profound degrees of SNHL are considered [20]. The only other report from sub-Saharan Africa was from Nigeria, which reported ANSD prevalence of 15.9% in SNHL cases for a cohort of babies born outside of hospital and 10.3% for a cohort born in hospital [10].…”

Section: Discussionmentioning

confidence: 98%

Childhood hearing loss and risk profile in a South African population

Swanepoel

Johl

Pienaar

2013

International Journal of Pediatric Otorhinolaryngology

View full text Add to dashboard Cite

Objective: To describe the nature of hearing loss and associated risk profile in a representative South African population of infants and children diagnosed at a pediatric referral clinic. Methods:A retrospective review of patient files for a pediatric auditory evoked potential clinic in Pretoria was conducted (January 2007 to December 2011).Collected data included demographical information, risk factors from case history questionnaire, diagnosis (type and degree of hearing loss), documented age of caregiver suspicion and age of first diagnosis. Results:Hearing loss was present in 73% (73/100) of cases evaluated. Permanent hearing losses (SNHL, ANSD & Mixed) constituted 76% of losses. Unilateral hearing losses constituted 8% of SNHL and 20% of conductive hearing loss. ANSD was diagnosed in 21.4% and SNHL in 78.6% of permanent non-conductive hearing loss cases. The most prevalent SNHL risk was family history of hearing loss and for ANSD it was admittance to the NICU for more than 5 days. The majority of the sample was diagnosed with a permanent bilateral SNHL and ANSD after 36 months of age (47%) despite 40% already suspected of having a hearing loss before 12 months of age. Conclusions:A high prevalence of ANSD was found with preventable risk factors often indicated. Age of diagnosis was significantly delayed, evidencing the lack of early hearing detection services in South Africa. The majority of children were diagnosed at ages precluding optimal benefits from early detection and subsequent intervention.3

show abstract

“…It is estimated that 5–15% of all children with sensorineural hearing loss (SNHL) exhibit symptoms of ANSD (Uus & Bamford, 2006; Kirkim et al, 2008; Talaat et al, 2009; Berlin et al, 2010; Maris et al, 2011; Roush et al, 2011; Bielecki et al, 2012; Mittal et al, 2012). The majority of these individuals present with bilateral ANSD.…”

Section: 1 Auditory Neuropathy Spectrum Disorder (Ansd): Descriptiomentioning

confidence: 99%

Cortical development and neuroplasticity in Auditory Neuropathy Spectrum Disorder

Sharma

Cardon

2015

Hearing Research

View full text Add to dashboard Cite

Cortical development is dependent to a large extent on stimulus-driven input. Auditory Neuropathy Spectrum Disorder (ANSD) is a recently described form of hearing impairment where neural dys-synchrony is the predominant characteristic. Children with ANSD provide a unique platform to examine the effects of asynchronous and degraded afferent stimulation on cortical auditory neuroplasticity and behavioral processing of sound. In this review, we describe patterns of auditory cortical maturation in children with ANSD. The disruption of cortical maturation that leads to these various patterns includes high levels of intra-individual cortical variability and deficits in cortical phase synchronization of oscillatory neural responses. These neurodevelopmental changes, which are constrained by sensitive periods for central auditory maturation, are correlated with behavioral outcomes for children with ANSD. Overall, we hypothesize that patterns of cortical development in children with ANSD appear to be markers of the severity of the underlying neural dys-synchrony, providing prognostic indicators of success of clinical intervention with amplification and/or electrical stimulation.

show abstract

Auditory neuropathy spectrum disorder: Its prevalence and audiological characteristics in an Indian tertiary care hospital

Cited by 29 publications

References 12 publications

Profound childhood hearing loss in a South Africa cohort: Risk profile, diagnosis and age of intervention

Profound childhood hearing loss in a South Africa cohort: Risk profile, diagnosis and age of intervention

Childhood hearing loss and risk profile in a South African population

Cortical development and neuroplasticity in Auditory Neuropathy Spectrum Disorder

Contact Info

Product

Resources

About