Atypical Presentation of Fungal Dacryocystitis

Purgason, Polly A.; Hornblass, Albert; Loeffler, Michael

doi:10.1016/s0161-6420(92)31788-9

Cited by 15 publications

(9 citation statements)

References 11 publications

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“…Bacteria are the etiological agents in 95% of patients with acquired dacryocystitis, with aerobic and facultative anerobic bacteria predominating; fungi were found to account for only 5% of infections in two studies (41,177 (114,177,213,226,304,424), the significance of some of these isolates is doubtful, on the basis of the criteria described previously (237). Infections due to S. schenckii and Acremonium spp.…”

Section: Mycotic Dacryocystitismentioning

confidence: 96%

“…are reported to generally manifest as chronic suppurative dacryocystitis; there may be preauricular and submaxillary lymphadenitis, and an abscess may develop which ruptures outside, resulting in an indolent ulcer (28). Aspergillus spp., Candida spp., Paecilomyces spp., R. seeberi, and dermatophytes may cause chronic granulomatous dacryocystitis (178,199,200,213,226,304).…”

Section: Mycotic Dacryocystitismentioning

confidence: 99%

“…Dacryocystitis following plugging of the lacrimal sac by A. fumigatus was reported to have been relieved after the plug was removed by opening the lacrimal sac; dacryocystorhinostomy did not have to be performed, and the patient was symptom free 1 year after the procedure (200). Dacryocystitis due to C. albicans resolved with surgery alone in one patient and with surgery and topical miconazole and natamycin therapy in another (304). Some patients with congenital dacryocystitis were reported to respond satisfactorily to topical antifungals, probing, and syringing (114), although complete details of the therapy were not provided in the report.…”

Section: Mycotic Dacryocystitismentioning

confidence: 99%

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Current Perspectives on Ophthalmic Mycoses

2003

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Fungi may infect the cornea, orbit and other ocular structures. Species of Fusarium, Aspergillus, Candida, dematiaceous fungi, and Scedosporium predominate. Diagnosis is aided by recognition of typical clinical features and by direct microscopic detection of fungi in scrapes, biopsy specimens, and other samples. Culture confirms the diagnosis. Histopathological, immunohistochemical, or DNA-based tests may also be needed. Pathogenesis involves agent (invasiveness, toxigenicity) and host factors. Specific antifungal therapy is instituted as soon as the diagnosis is made. Amphotericin B by various routes is the mainstay of treatment for life-threatening and severe ophthalmic mycoses. Topical natamycin is usually the first choice for filamentous fungal keratitis, and topical amphotericin B is the first choice for yeast keratitis. Increasingly, the triazoles itraconazole and fluconazole are being evaluated as therapeutic options in ophthalmic mycoses. Medical therapy alone does not usually suffice for invasive fungal orbital infections, scleritis, and keratitis due to Fusarium spp., Lasiodiplodia theobromae, and Pythium insidiosum. Surgical debridement is essential in orbital infections, while various surgical procedures may be required for other infections not responding to medical therapy. Corticosteroids are contraindicated in most ophthalmic mycoses; therefore, other methods are being sought to control inflammatory tissue damage. Fungal infections following ophthalmic surgical procedures, in patients with AIDS, and due to use of various ocular biomaterials are unique subsets of ophthalmic mycoses. Future research needs to focus on the development of rapid, species-specific diagnostic aids, broad-spectrum fungicidal compounds that are active by various routes, and therapeutic modalities which curtail the harmful effects of fungus- and host tissue-derived factors

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Section: Mycotic Dacryocystitismentioning

confidence: 96%

Section: Mycotic Dacryocystitismentioning

confidence: 99%

Section: Mycotic Dacryocystitismentioning

confidence: 99%

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Current Perspectives on Ophthalmic Mycoses

2003

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“…Where investigated, yeasts such as Candida (30,120,208) or Rhodotorula (183) spp. have been implicated.…”

Section: Infections Of Adjacent Structuresmentioning

confidence: 99%

Fungal and Parasitic Infections of the Eye

Klotz

Penn

Negvesky

et al. 2000

Clinical Microbiology Reviews

181

145

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“…La etiología de esta infección suele ser bacteriana. La etiología micótica de las dacriocistitis cró-nicas es poco frecuente, a pesar de que los hongos son causa conocida de diferentes infecciones oculares y corneales (1,2). Sin embargo, el papel de los hongos como causantes de las obstrucciones del conducto nasolacrimal no está aclarado (1,2).…”

Section: Introductionunclassified

Dacriocistitis por Candida Lusitaniae

Pastor-Pascual

España‐Gregori

Aviñó-Martínez

et al. 2007

Arch Soc Esp Oftalmol

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RESUMENCaso clínico: Se presenta el caso de una mujer de 60 años con episodios recurrentes de dacriocistitis aguda derecha que no cedían con tratamiento médi-co ni tras una dacriocistorrinostomía con intubación bicanalicular. Presentó también una dacriocistitis izquierda que requirió una dacriocistorrinostomía. Se tomaron muestras intraoperatorias y en el cultivo apareció Candida Lusitaniae como germen responsable. Tras tratamiento tópico con Anfotericina B, asociado a dacriocistorrinostomía, la clínica desapareció. Discusión: La dacriocistitis por Candida Lusitaniae es muy rara. Cabría preguntarse si Candida Lusitaniae es el germen primario o la dacriocistitis podría ser por sobreinfección fúngica debido al tratamiento antibiótico de las distintas dacriocistitis agudas sufridas.Palabras clave: Candida Lusitaniae, dacriocistitis crónica, dacriocistitis fúngica, dacriocistorrinostomía, anfotericina B. COMUNICACIÓN CORTA ABSTRACTCase report: We report the case of a 60-year-old woman with recurrent dacryocystitis of the right lacrimal sac. She did not recover after medical treatment, nor after dacryocystorhinostomy with canalicular intubation. She also had dacryocystitis on the left side. The material that was obtained during surgery was grown in a culture medium and Candida Lusitaniae was identified as the responsible organism. All symptoms disappeared after topical treatment with amphotericin B and dacryocystorhinostomy. Discussion: Dacryocystitis caused by Candida Lusitaniae is very rare. We should always consider whether Candida Lusitaniae is responsible for the primary infection or is the agent resulting from a superadded infection caused by previous antibiotic therapy (Arch Soc Esp Oftalmol 2007; 82: 365-368).

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Atypical Presentation of Fungal Dacryocystitis

Cited by 15 publications

References 11 publications

Current Perspectives on Ophthalmic Mycoses

Current Perspectives on Ophthalmic Mycoses

Fungal and Parasitic Infections of the Eye

Dacriocistitis por Candida Lusitaniae

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