Atualização sobre hemoglobina glicada (HbA1C) para avaliação do controle glicêmico e para o diagnóstico do diabetes: aspectos clínicos e laboratoriais

Netto, Augusto Pimazoni; Andriolo, Adagmar; Filho, Fadlo Fraige; Tambascia, Marcos Antônio; Gomes, Marília de Brito; Melo, Murilo Rezende; Sumita, Nairo Massakazu; Lyra, Rüy; Cavalcanti, Saulo

doi:10.1590/s1676-24442009000100007

Cited by 59 publications

(41 citation statements)

References 12 publications

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“…Enabling factors, such as diabetes mellitus, may affect the growth of human conjunctival microbiota, increasing the risk of eye infection (4) . Diabetes mellitus is a group of metabolic diseases resulting from defects in insulin action and secretion, leading to a hyperglycemic (5) . Measurement of glycated hemoglobin is the gold-standard test in the assessment of glycemic control in patients with diabetes mellitus and is a useful test in the follow-up of diabetic patients, as well as in the assessment of the status of blood glucose over the previous 3 months (6,7) .…”

Section: Introductionmentioning

confidence: 99%

Aerobic bacterial microbiota of the conjunctiva in diabetic patients with normal and altered glycated hemoglobin levels in two regions in Brazil

Moreno¹,

Moreno²,

Sousa³

2014

Arquivos Brasileiros De Oftalmologia

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Purpose: To study the aerobic bacterial microbiota of the conjunctiva in diabetic patients with regard to the management of diabetes, assessed using glycated hemoglobin levels. Methods: A cross-sectional study was conducted using conjunctival smears of diabetic patients from both sexes and with different ages, residing in two different Brazilian cities (Sorocaba and Rio Branco). A control group of non-diabetic patients was also included. The diabetic patients were considered to have controlled diabetes when their glycated hemoglobin level was ≤7% and blood glucose level was ≤126 mg/dL. Patients with non-controlled diabetes were those with glycated hemoglobin levels >7% and blood glucose levels >126 mg/dL. The samples obtained were inoculated in Brain-Heart Infusion broth and in culture media for aerobic bacteria (blood and chocolate agars); bacterial growth was evaluated in a microbiology laboratory. Results: A total of 120 eyes of 120 patients were included in the present study. The percentage of cultures in which bacterial growth was observed was greater in diabetic patients, although the difference was not statistically significant (p=0.103). There was a greater trend toward bacterial growth in the conjunctiva of diabetic patients with altered fasting blood glucose. There was no difference in the frequency of bacterial growth on the conjunctiva between diabetic patients with normal or altered glycated hemoglobin levels. In Sorocaba, conjunctival bacterial growth was similar to that observed in Rio Branco. The microorganism most frequently detected in the present study was Staphylococcus epidermidis, followed by Staphylococcus aureus, Proteus mirabilis, and Escherichia coli. Conclusions: There was no difference between diabetic patients with normal or altered glycated hemoglobin levels. The microorganisms found were similar to those found in studies investigating the conjunctival bacterial flora of diabetic and non-diabetic patients.

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Section: Introductionmentioning

confidence: 99%

Aerobic bacterial microbiota of the conjunctiva in diabetic patients with normal and altered glycated hemoglobin levels in two regions in Brazil

Moreno¹,

Moreno²,

Sousa³

2014

Arquivos Brasileiros De Oftalmologia

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“…14,[25][26][27] Over the years, prolonged hyperglycemia can cause extensive and irreversible organic wounds, affecting the eyes, kidney, nerves, large and small vessels, as well as blood coagulation. 33 Findings from the United Kingdom Prospective Diabetes Study (UKPDS) confirm that the ideal glycemic control in patients with DM2 reduces the development and advancement of a large number of complications resulting from the disease. 34 Differently from glycemic tests, which reflect the glycemic levels at the exact moment of measurement, the HbA1c tests indicate the average glucose levels from the last two to four months.…”

Section: Discussionmentioning

confidence: 99%

“…33 Therefore, the last two to three months need to be considered when measuring it, and this is an important recommendation when testing treatment effectiveness. 35 Taking into consideration the measurement of HbA1c levels at the end of the interventions carried out in each of the analyzed studies in the present research, eight of them 4,24-30 complied with the recommendations of the Brazilian Diabetes Society (SBD) and measured the HbA1c levels after two, 28 three to six 4,[25][26]30 and twelve months of intervention.…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of telephone interventions as a strategy for glycemic control: an integrative literature review

Vasconcelos

Freitas

Marinho³

et al. 2013

Texto contexto - enferm.

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ABSTRACT:The objective of this study was to analyze the effectiveness of telephone interventions as a strategy for glycemic control in adult Type 2 Diabetes Mellitus patients. An integrative literature review was undertaken in April and May 2011 through surveys in the Cochrane, PubMed/Medline, Lilacs and Cinahl databases. Nine studies complied with the inclusion criteria, mainly randomized controlled clinical trials. Concerning the time period analyzed in each study, it varied from eight weeks to twelve months. 1294 patients participated in the study, being 671 randomized to telephone follow-ups and 479 to usual care. In eight studies analyzed, glycemic control was based on the levels of glycated hemoglobin (HbA1c). The information found showed that the interventions are effective for glycemic control in patients who have type 2 Diabetes. Self-management was improved and possible complications of the disease were reduced. El objetivo fue analizar la eficacia de intervenciones que usan el teléfono como estrategia para el control glucémico de adultos con Diabetes Mellitus tipo 2. Se trata de una revisión integradora llevada a cabo de abril a mayo de 2011 a través de la búsqueda en las bases de datos Cochrane, PubMed/Medline, Lilacs y Cinahl. Nueve estudios cumplieron los criterios de inclusión, prevaleciendo entre ellos los ensayos aleatorios y controlados. Mientras al seguimiento, hubo variación de ocho semanas a doce meses. Participaron 1.294 pacientes, 671 aleatorios para seguimiento telefónico y 479 con atención habitual. El control de la glucemia fue determinado por niveles de hemoglobina glucosilada (HbA1c) en ocho estudios analizados. Las informaciones que se encontraron señalaron que las intervenciones son efectivas en el control glucémico de pacientes con Diabetes tipo 2. El autocontrol estuvo mejorado y la reducción de las posibles complicaciones de la enfermedad fue potencializada. DESCRIPTORS: DESCRIPTORES:Diabetes mellitus tipo 2. Teléfono. Estudios de intervención. Enfermería.

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“…O termo HbA1C refere-se a união entre a hemoglobina A (HbA) e alguns açucares através de reações não-enzimática continua, lenta e irreversível definida como glicação e ocorre em maior ou menor grau, conforme o nível de glicemia (SUMITA; ANDRIOLO, 2008;NETTO et al, 2009). A quantidade de glicose ligada a hemoglobina é diretamente proporcional a concentração média de glicose no sangue e a meia vida dos eritrócitos, sendo capaz de fornecer uma avaliação do controle glicêmico médio no período de 90 a 120 dias que antecedem a coleta de sangue para o exame (CAVAGNOLLI, 2009;SBD, 2013SBD, -2014.…”

Section: Fonte: Elaborado Pelos Autoresunclassified

Perfil Sociodemográfico, Bioquímico E Hematológico De Idosos Residentes Do Município De Ivoti/Rs

Berlese

Silva

Santos

et al. 2018

RCO

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O envelhecimento populacional é um fenômeno mundial que vem ocorrendo de forma rápida nos países em desenvolvimento. Este trabalho buscou conhecer as características dos idosos residentes de Ivoti/RS no intuito de contribuir e retardar problemas de saúde pública relacionados ao envelhecimento da população. Através de um estudo quantitativo transversal com 160 idosos do munícipio de Ivoti/RS, foi realizado um questionário sócio demográfico e coleta de amostras biológicas para análise bioquímicas e hematológicas. Nos resultados, obtivemos uma maioria (73,8%) de mulheres participantes, casados (57,5%), aposentados (100%), com renda familiar de até dois salários mínimos (58,1%), com escolaridade até 4º série (42,5%) e bilíngue (68,8%). Ao analisar as variáveis bioquímicas e hematológicas por sexo, não se obteve diferença estatística e os valores estão dentro do preconizado pela literatura. Os resultados encontrados nesse estudo apontam para o envelhecimento bem-sucedido nos idosos residentes no município de Ivoti/RS.Palavras-chave: Idoso. Envelhecimento. Perfil Bioquímico. Perfil Hematológico. ABSTRACT Population aging is a fast-growing global phenomenon in developing countries. This work aimed to know the characteristics of elderly residentes of Ivoti/Rs, in order to contribute to and delay public health problems related to the aging of the population. A cross-sectional quantitative study with 160 elderly individuals from the municipality of Ivoti/Rs, carried out a sócio-demographic questionnaire and collection of biological samples for biochemical and hematological analysis. In the results, we obtained a majority (73,8%) of women, married (57,5%), redired (100%), with a Family income of up to two minimum wages (58,1%), series (42,5%) and bilingual (68,8%). When analyzing the biochemical and hematological variables by sex, no statistical difference was obtained and the values are within the recommended by the literature. The results found in this study point to the successful aging of the elderly in the monicipality of Ivoti/Rs. Keywords: Old man. Aging. Profile Biochemist. Profile Hematologic.

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Atualização sobre hemoglobina glicada (HbA1C) para avaliação do controle glicêmico e para o diagnóstico do diabetes: aspectos clínicos e laboratoriais

Cited by 59 publications

References 12 publications

Aerobic bacterial microbiota of the conjunctiva in diabetic patients with normal and altered glycated hemoglobin levels in two regions in Brazil

Aerobic bacterial microbiota of the conjunctiva in diabetic patients with normal and altered glycated hemoglobin levels in two regions in Brazil

Effectiveness of telephone interventions as a strategy for glycemic control: an integrative literature review

Perfil Sociodemográfico, Bioquímico E Hematológico De Idosos Residentes Do Município De Ivoti/Rs

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