Attenuation of short wavelengths alters sleep and the ip<scp>RGC</scp> pupil response

Ostrin, Lisa A; Abbott, Kaleb S.; Queener, Hope M

doi:10.1111/opo.12385

Cited by 53 publications

(60 citation statements)

References 66 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A simple solution that may effectively block and reduce the blue portion of the light spectrum before bedtime are blue light blocking glasses and lenses . Wearing blue light blocking eyewear before and during bed time may effectively attenuate LED induced melatonin suppression and thus can potentially facilitate the adaption to new social schedules and reduce sleep disturbances and their consequences among the general population. Further, a reduction of the blue portion in artificial light during nighttime hours could protect shift workers against disorders such as cancer and cardiovascular disorders.…”

Section: Countermeasures For the Altering Effects Of The Blue Lightmentioning

confidence: 99%

The inner clock—Blue light sets the human rhythm

Wahl

Engelhardt

Schaupp

et al. 2019

Journal of Biophotonics

170

113

View full text Add to dashboard Cite

Visible light synchronizes the human biological clock in the suprachiasmatic nuclei of the hypothalamus to the solar 24‐hour cycle. Short wavelengths, perceived as blue color, are the strongest synchronizing agent for the circadian system that keeps most biological and psychological rhythms internally synchronized. Circadian rhythm is important for optimum function of organisms and circadian sleep–wake disruptions or chronic misalignment often may lead to psychiatric and neurodegenerative illness. The beneficial effect on circadian synchronization, sleep quality, mood, and cognitive performance depends not only on the light spectral composition but also on the timing of exposure and its intensity. Exposure to blue light during the day is important to suppress melatonin secretion, the hormone that is produced by the pineal gland and plays crucial role in circadian rhythm entrainment. While the exposure to blue is important for keeping organism's wellbeing, alertness, and cognitive performance during the day, chronic exposure to low‐intensity blue light directly before bedtime, may have serious implications on sleep quality, circadian phase and cycle durations. This rises inevitably the need for solutions to improve wellbeing, alertness, and cognitive performance in today's modern society where exposure to blue light emitting devices is ever increasing.

show abstract

Section: Countermeasures For the Altering Effects Of The Blue Lightmentioning

confidence: 99%

The inner clock—Blue light sets the human rhythm

Wahl

Engelhardt

Schaupp

et al. 2019

Journal of Biophotonics

170

113

View full text Add to dashboard Cite

show abstract

“…People who wear “blue‐light goggles” that allow more blue light into the eyes while concurrently looking at computer monitors have significantly decreased nighttime melatonin levels compared to subjects only exposed to monitor light at night (Figueiro, Wood, Plitnick, & Rea, ). Attenuation of blue light by wearing short wavelength‐blocking glasses prior to bedtime significantly increases the nighttime melatonin level and improves the sleep quality and duration (Ostrin, Abbott, & Queener, ).…”

Section: Melanopsin‐expressing Intrinsically Photosensitive Retinal Gmentioning

confidence: 99%

Circadian regulation in the retina: From molecules to network

2018

Eur J of Neuroscience

View full text Add to dashboard Cite

The mammalian retina is the most unique tissue among those that display robust circadian/diurnal oscillations. The retina is not only a light sensing tissue that relays light information to the brain, it has its own circadian “system” independent from any influence from other circadian oscillators. While all retinal cells and retinal pigment epithelium (RPE) possess circadian oscillators, these oscillators integrate by means of neural synapses, electrical coupling (gap junctions), and released neurochemicals (such as dopamine, melatonin, adenosine, and ATP), so the whole retina functions as an integrated circadian system. Dysregulation of retinal clocks not only causes retinal or ocular diseases, it also impacts the circadian rhythm of the whole body, as the light information transmitted from the retina entrains the brain clock that governs the body circadian rhythms. In this review, how circadian oscillations in various retinal cells are integrated, and how retinal diseases affect daily rhythms.

show abstract

“…Exposure to blue light at night time can lead to suppression of melatonin secretion which disrupts the circadian clock and may cause adverse consequences on mental, physical health, and sleep . The disruption of circadian rhythm is associated with mood disorders, breast cancer, obesity and chronic diseases, heart disease, high blood pressure, and other cardiovascular problems .…”

mentioning

confidence: 99%

Modelling the effect of commercially available blue‐blocking lenses on visual and non‐visual functions

Alzahrani

Khuu

Roy

2020

Clinical and Experimental Optometry

View full text Add to dashboard Cite

Background: Blue-blocking lenses (BBLs) are marketed as providing retinal protection from acute and cumulative exposure to blue light over time. The selective reduction in visible wavelengths transmitted through BBLs is known to influence the photosensitivity of retinal photoreceptors, which affects both visual and non-visual functions. This study measured the spectral transmittance of BBLs and evaluated their effect on blue perception, scotopic vision, circadian rhythm, and protection from photochemical retinal damage. Methods: Seven different types of BBLs from six manufacturers and untinted control lenses with three different powers (+2.00 D, −2.00 D and Plano) were evaluated. The whiteness index of BBLs used in this study was calculated using Commission International de l'Eclairage (CIE) Standard Illuminates D65, and CIE 1964 Standard with a 2 Observer. The protective qualities of BBLs and their effect on blue perception, scotopic vision, and circadian rhythm were evaluated based on their spectral transmittance, which was measured with a Cary 5,000 UV-Vis-NIR spectrophotometer. Results: BBLs were found to reduce blue light (400-500 nm) by 6-43 per cent, providing significant protection from photochemical retinal damage compared to control lenses (p ≤ 0.05). All BBLs were capable of reducing the perception of blue colours, scotopic sensitivities and circadian sensitivities by 5-36 per cent, 5-24 per cent, and 4-27 per cent, respectively depending on the brand and power of the lens. Conclusion: BBLs can provide some protection to the human eye from photochemical retinal damage by reducing a portion of blue light that may affect visual and non-visual performances, such as those critical to scotopic vision, blue perception, and circadian rhythm.

show abstract

Attenuation of short wavelengths alters sleep and the ipRGC pupil response

Cited by 53 publications

References 66 publications

The inner clock—Blue light sets the human rhythm

The inner clock—Blue light sets the human rhythm

Circadian regulation in the retina: From molecules to network

Modelling the effect of commercially available blue‐blocking lenses on visual and non‐visual functions

Contact Info

Product

Resources

About