Attention impairment in childhood absence epilepsy: An impulsivity problem?

Neuromagnetic high-frequency oscillations correlate with seizure severity in absence epilepsy

“…Studies focusing on early pre-ictal sources have demonstrated that spike and wave discharges (SWDs) do not suddenly increase but gradually build up over a dynamic network and are preceded by low-frequency occipital and frontal sources (Gupta et al, 2011). Children with CAE commonly present with psychological problems, even if their seizures are controlled (Cerminara et al, 2013;Glauser et al, 2013). Considering that HFOs occurring in different patterns are likely to have different neurophysiological mechanisms and clinical relevance Kobayashi et al, 2013), this study quantitatively characterized the neuromagnetic signatures and clinical correlations of interictal and ictal activities from low-to very-high-frequency ranges in patients with CAE.…”

Go and NoGo: modulation of electrophysiological correlates by female sex steroid hormones

“…EEG and ERPs, being widely available, enable study of the precise timing of response-related network activation by placing recording electrodes on the scalp and naming them accordingly (F for frontal portion of the head, P for parietal and C-to the center of the head with even numbers referring to the right side of the head and odd-to the left, z indicating midline). The ERPs obtained during the Go/NoGo paradigm were recently applied to investigate inhibitory processes in clinical populations: epilepsy (Cerminara et al 2013), drug and alcohol dependence (Oddy and Barry 2009), depression (Ruchsow et al 2008b;Bailey et al 2014), obsessive-compulsive disorder (Ruchsow et al 2007), borderline personality disorder (Ruchsow et al 2008a), schizophrenia (Weisbrod et al 2000), and Parkinson's disease (Beste et al 2009). Responses in the Go/NoGo task may inform about the efficacy of antidepressant treatment (Gyurak et al 2015) and may help to differentiate between schizophrenia, bipolar disorder, and schizoaffective disorder (Chun et al 2013).…”

Temporal lobe epilepsy: Decreased thalamic resting-state functional connectivity and their relationships with alertness performance

“…Additionally, in a systemic review of rolandic epilepsy, researchers found that the alertness network is impaired in patients with active centrotemporal spikes [21]. Behavioral data also suggest that tonic alertness and phasic alertness are impaired in childhood absence epilepsy [22]. In brief, these reviewed studies revealed the increasing attention that has been given to alertness dysfunctions in epilepsy.…”