Atopy patch test (APT) in the diagnosis of food allergy in children with atopic dermatitis

Levy, Soloni Afra Pires; Dortas, Sérgio Duarte; Pires, Andréa H. S.; Abe, Augusto Tiaqui; Valle, Solange Oliveira Rodrigues; Coelho, Vilma Perez; Hahnstadt, Ludwig Ruppert; França, Alfeu Tavares

doi:10.1590/s0365-05962012000500009

Cited by 13 publications

(6 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…65,66 The subgroup of moderate to severe AD have a higher risk of sensitization to food allergens and this is translated into a high risk of true food allergy. 65,67,68 The clinical history, along with an allergology evaluation, can help to identify suspect foods, but it is necessary to verify with restriction diets for 3 to 4 weeks or controlled oral challenges.…”

Section: Can Restriction Diet Help As a Treatment Of Atopic Dermatitis?mentioning

confidence: 99%

Systematic review about 10 interventions in dermatitis. A document from the Latin American Society of Allergy, Asthma, and Immunology

Sánchez

Sánchez²,

Macías-Weinmann

et al. 2019

RAM

View full text Add to dashboard Cite

The Latin American Society of Allergy, Asthma, and Immunology (SLAAI) conducted a systematic search in the Medline and LILACS' database in order to get articles linked to 10 current questions about dermatitis. The assessment of the quality of the evidence and the strength of the recommendations was made through the GRADE system. The completeness and transparency of the recommendations for this clinical guide were assessed with the AGREE Reports Verification Checklist. The final document was shared with physicians, allergists, dermatologists, and pediatricians, and with patients and academic institutions such as universities and medical scientific societies for external assessment. According to the review, clinical scales should be used to measure the severity of the dermatitis, and some interventions such as the use of probiotics may benefit the patient; nevertheless, more studies are required before this management option can be used in the everyday practice. Other interventions such as dietary restrictions and the use of antihistamines seem to be well-founded only in particular cases and they should not be a general recommendation for all patients. This practical guide presents recommendations for the treatment of atopic dermatitis; these recommendations can be helpful for medical staff, patients, and health systems.

show abstract

Section: Can Restriction Diet Help As a Treatment Of Atopic Dermatitis?mentioning

confidence: 99%

Systematic review about 10 interventions in dermatitis. A document from the Latin American Society of Allergy, Asthma, and Immunology

Sánchez

Sánchez²,

Macías-Weinmann

et al. 2019

RAM

View full text Add to dashboard Cite

show abstract

“…History, sIgE, and SPT are almost only used to identify type I (IgE-mediated) reactions. However, despite some limitations to its use, the gold standard for food allergy is still the double-blind, placebo-controlled, oral food challenge [8].…”

Section: Discussionmentioning

confidence: 99%

Is the Atopy Patch Test Reliable in the Evaluation of Food Allergy-Related Atopic Dermatitis?

Mansouri

Rafiee²,

Darougar³

et al. 2018

Int Arch Allergy Immunol

View full text Add to dashboard Cite

Background: Aeroallergens and food allergens are found to be relevant in atopic dermatitis. The atopy patch test (APT) can help to detect food allergies in children with atopic dermatitis. This study evaluates if the APT is a valuable tool in the diagnostic workup of children with food allergy-related atopic dermatitis. Methods: 42 children between 6 months and 12 years of age were selected at the Mofid Children Hospital. Atopic dermatitis was diagnosed, and the severity of the disease was determined. At the test visit, the patients underwent a skin prick test (SPT), APT, and serum IgE level measurement for cow's milk, egg yolk, egg white, wheat, and soy. Results: We found a sensitivity of 91.7%, a specificity of 72.7%, a positive predictive value (PPV) of 88%, a negative predictive value (NPV) of 80%, and an accuracy of 85.7% for APT performed for cow's milk. APT performed for egg yolk had a sensitivity and a NPV of 100%, while the same parameters obtained with egg white were 84.2 and 75%, respectively. The sensitivity, specificity, and NPV of the APT for wheat were 100, 75, and 100%, respectively. The sensitivity, PPV, and NPV of the APT for soy were 87.5, 70, and 87.5%, respectively. Conclusions: Our data demonstrate that the APT is a reliable diagnostic tool to evaluate suspected food allergy-related skin symptoms in childhood and infancy.

show abstract

“…En niños menores de dos años de edad, un habón de 5 mm o más tiene un VPP de 95 % (56). La prueba epidérmica de parche es útil principalmente en pacientes con dermatitis atópica y trastornos gastrointestinales con eosinofilia o sin ella; sin embargo, sus valores pronóstico y su estandarización aún no está claramente definida (57).…”

Section: Diagnósticounclassified

“…Sin embargo, algunos estudios publicados principalmente en México (81,82) y Brasil (57,83) reportan que, aunque ambos alimentos son las fuentes más usuales de alérgenos, la frecuencia encontrada es menor que en Europa y Estados Unidos y que otras fuentes, como el maíz y algunas frutas y verduras, tienen una frecuencia similar de sensibilización que incluso es mayor en algunas ciudades. Estos datos indican que las costumbres alimenticias, las características genéticas y el tipo de ambiente influyen de manera importante.…”

Section: Consideraciones Para América Latinaunclassified

Alergia a la leche y al huevo: diagnóstico, manejo e implicaciones en América Latina

Sánchez¹,

Restrepo

Mopan

et al. 2013

biomedica

View full text Add to dashboard Cite

La sensibilización a alimentos y el desarrollo de alergias alimentarias viene aumentando en todo el mundo, siendo la leche de vaca y el huevo de gallina los principales alimentos implicados. En la mayoría de los países latinoamericanos no existen guías de manejo y cuando se elaboren deberán adaptarse a las condiciones de la población de cada región. En el presente artículo presentamos una revisión del manejo de la alergia alimentaria a la leche y al huevo útil para el personal de salud de todos los niveles, así como algunas consideraciones de los factores presentes en los países latinoamericanos.Palabras clave: alergia e inmunología, hipersensibilidad al huevo, hipersensibilidad a la leche, alimentos, anafilaxia, dieta, desensibilización inmunológica, inmunoterapia, tolerancia. doi: http://dx.doi.org/10.7705/biomedica.v34i1.1677 Milk and egg allergy: Diagnosis, management and implications for Latin AmericaSensitization to food allergens, as well as the development of food allergies, is increasing worldwide, and cow's milk and hen's eggs are the main implicated foods. In most Latin American countries there are no management guidelines on the aforementioned topics; at their creation, such guidelines should be adapted to the conditions of the population in each region. This paper presents a review of the management of food allergy to milk and eggs useful for health personnel at all levels and some considerations of the factors found in Latin American developing countries.Keywords: Allergy and immunology, egg hypersensitivity, milk hypersensitivity, food, anaphylaxis, diet; desensitization, immunologic; immunotherapy, permissiveness. doi: http://dx.doi.org/10. 7705/biomedica.v34i1.1677 Las reacciones adversas a los alimentos se producen por una gran variedad de mecanismos que incluyen el sistema inmunitario, los procesos enzimáticos, las reacciones fisiológicas y los componentes psicológicos (1). Cuando se demuestra un mecanismo inmune, se le denomina alergia a alimentos, y si se encuentran niveles elevados de inmunoglobulina E (IgE) específica para alérgenos de alimentos con relevancia clínica, se habla de alergia alimentaria mediada por IgE (2). Igualmente, se pueden presentar reacciones alérgicas a alimentos mediadas por mecanismos celulares y alergias alimentarias mixtas, en las cuales participan los dos mecanismos anteriores.Los alimentos implicados y la frecuencia de las reacciones dependen de los hábitos y costumbres alimentarias en los distintos países, al igual que de los parámetros metodológicos utilizados en los diferentes estudios. Se estima que la prevalencia de reacciones adversas a alimentos es de entre 13 y 43 %, según informes de los padres de niños preescolares (3,4); sin embargo, solo una parte de las reacciones reportadas en dichos informes se deben realmente a un alimento; en un estudio en el que 28 % de los pacientes había

show abstract

Atopy patch test (APT) in the diagnosis of food allergy in children with atopic dermatitis

Cited by 13 publications

References 13 publications

Systematic review about 10 interventions in dermatitis. A document from the Latin American Society of Allergy, Asthma, and Immunology

Systematic review about 10 interventions in dermatitis. A document from the Latin American Society of Allergy, Asthma, and Immunology

Is the Atopy Patch Test Reliable in the Evaluation of Food Allergy-Related Atopic Dermatitis?

Alergia a la leche y al huevo: diagnóstico, manejo e implicaciones en América Latina

Contact Info

Product

Resources

About