Atomic Spectroscopy

Bings, Nicolas H.; Bogaerts, Annemie; Broekaert, J. A. C.

doi:10.1021/ac8006297

Cited by 63 publications

(42 citation statements)

References 338 publications

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“…These features have made CE also interesting for the analysis of interactions of transition-metal complexes with proteins, especially when coupled to inductively coupled plasma mass spectrometry (ICP-MS) as the detector. [16] The binding towards serum proteins is considered essential for the transport of the drug to the target but can also be a reason for undesired side-effects and was therefore also of great interest in this study. [17][18][19] …”

Section: Introductionmentioning

confidence: 99%

New Insights into the Chemistry of the Antineoplastic Lanthanum Complex Tris(1,10‐phenanthroline)tris(thiocyanato‐κN)lanthanum(III) (KP772) and Its Interaction with Biomolecules

et al. 2009

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The lanthanide complex tris(1,10‐phenanthroline)tris(thiocyanato‐κN)lanthanum(III) [La(phen)3(NCS)3] (KP772) is a promising anticancer drug candidate, capable of overcoming resistance of tumors to established chemotherapeutics. The compound was characterized by elemental analysis, IR, 1H NMR spectroscopy, TG/DTA measurements, mass spectrometry and X‐ray diffraction analysis. The results indicate that KP772 is a neutral, nine‐coordinate complex. In addition the behavior in water, important for the application as a chemotherapeutic drug, and the binding to biomolecules was investigated by capillary electrophoresis and ICP‐MS.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)

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Section: Introductionmentioning

confidence: 99%

New Insights into the Chemistry of the Antineoplastic Lanthanum Complex Tris(1,10‐phenanthroline)tris(thiocyanato‐κN)lanthanum(III) (KP772) and Its Interaction with Biomolecules

et al. 2009

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“…In the suspension sampling, a small amount of solid is ground and dispersed in a suitable solvent, forming a liquid-solid suspension, which minimizes the use of reagents and contamination risks [42] making faster analysis [43]. This technique was employed initially by Brady et al [44,45] making it a very attractive technique since the handling of the sample is minimal [43,46].…”

Section: Suspensionmentioning

confidence: 99%

Strategies to increase selectivity of analytical methods for As, Cr and Se speciation in biological samples: A review

Carvalho¹,

Coelho²,

Coelho³

et al. 2014

Sample Preparation

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Abstract:This review provides an overview and discusses different analytical strategies that minimize or eliminate the preparation of samples for speciation of organic and inorganic species of As, Cr and Se in samples of biological interest. These metals are important for the human body and the presence of various chemical forms of metals determines its essentiality and toxicity, thus speciation comes as an important tool for the study of biological samples. However, speciation requires a reduction in the steps of sample preparation, allowing a sample investigation in its most native form in order to reduce the changes in chemical species. The strategies proposed for speciation of these metals include: solid phase extraction, point cloud extraction, suspension and direct analysis. Selected methods proposed for the speciation of organic and inorganic species of As, Cr and Se were reviewed including their main figures of merit, advantages and disadvantages.

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“…12,13 Accordingly, great efforts have been devoted to the development of the selective and sensitive detection methods. 14,15 Traditional heavy metal analysis methods include atomic absorption spectrometry [16][17][18] and inductively coupled plasma mass spectrometry; [19][20][21] however, these instrumentally intensive methods only measure the total metal ion content, and often require extensive sample preparation. Electrochemical analyses have also been commonly used to detect metal ions present in biological or environmental specimens.…”

Section: Introductionmentioning

confidence: 99%

Analytical strategies based on quantum dots for heavy metal ions detection

Vázquez‐González

Carrillo‐Carrión

2014

J. Biomed. Opt

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Abstract. Heavy metal contamination is one of the major concerns to human health because these substances are toxic and retained by the ecological system. Therefore, in recent years, there has been a pressing need for fast and reliable methods for the analysis of heavy metal ions in environmental and biological samples. Quantum dots (QDs) have facilitated the development of sensitive sensors over the past decade, due to their unique photophysical properties, versatile surface chemistry and ligand binding ability, and the possibility of the encapsulation in different materials or attachment to different functional materials, while retaining their native luminescence property. This paper comments on different sensing strategies with QD for the most toxic heavy metal ions (i.e., cadmium, Cd 2þ ; mercury, Hg 2þ ; and lead, Pb 2þ ). Finally, the challenges and outlook for the QD-based sensors for heavy metals ions are discussed.

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Atomic Spectroscopy

Cited by 63 publications

References 338 publications

New Insights into the Chemistry of the Antineoplastic Lanthanum Complex Tris(1,10‐phenanthroline)tris(thiocyanato‐κN)lanthanum(III) (KP772) and Its Interaction with Biomolecules

New Insights into the Chemistry of the Antineoplastic Lanthanum Complex Tris(1,10‐phenanthroline)tris(thiocyanato‐κN)lanthanum(III) (KP772) and Its Interaction with Biomolecules

Strategies to increase selectivity of analytical methods for As, Cr and Se speciation in biological samples: A review

Analytical strategies based on quantum dots for heavy metal ions detection

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