Abstract:This review provides an overview and discusses different analytical strategies that minimize or eliminate the preparation of samples for speciation of organic and inorganic species of As, Cr and Se in samples of biological interest. These metals are important for the human body and the presence of various chemical forms of metals determines its essentiality and toxicity, thus speciation comes as an important tool for the study of biological samples. However, speciation requires a reduction in the steps of sample preparation, allowing a sample investigation in its most native form in order to reduce the changes in chemical species. The strategies proposed for speciation of these metals include: solid phase extraction, point cloud extraction, suspension and direct analysis. Selected methods proposed for the speciation of organic and inorganic species of As, Cr and Se were reviewed including their main figures of merit, advantages and disadvantages.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.