Atomic layer deposition of zinc oxide on microrough zirconia to enhance osteogenesis and antibiosis

<p>The Fabrication and Function of Strontium-modified Hierarchical Micro/Nano Titanium Implant</p>

“…Accordingly, compared to the AH-Ti, the osteogenic related gene expression including ALP, RUNX2, OCN, OPN and COL-1 was statistically upregulated on AH-Ti/Sr90 substrates (P<0.05), which showed the most superior osteogenic differentiation ability. It exhibited that the AH-Ti/Sr90 substrates had the most suitable ion release property and surface topography, of which the robust synergistic function had been confirmed by Yao et al 52 In addition, the ALP expression was also statistically upregulated on AH-Ti/Sr30 and AH-Ti/Sr150 compared to AH-Ti and pure Ti (<0.05), which was mainly ascribed to the surface topography. According to previous studies, the cell proliferation and adhesion had…”

Behaviour of Vascular Smooth Muscle Cells on Amine Plasma-Coated Materials with Various Chemical Structures and Morphologies

“…The solid MoS 2 films showed no signs of cytotoxicity for six different cell types, but the presence of microparticles caused a concentration-dependent decrease in proliferation of all cell types that were used. A considerable number of other publications have reported concentration-dependent cytotoxic effects of silicon, SiO 2 , and ZnO microparticles [ 72 , 73 , 74 ], while SiO 2 and ZnO in the form of films demonstrated good biocompatibility without having a negative effect on cell proliferation [ 75 , 76 , 77 , 78 ]. Moreover, an in vivo study performed on rodents (mice and rats) by Taylor et al [ 79 ] revealed chronic inflammation and gross fibrin formation after the subcutaneous injection of kafirin microparticles 1–5 µm in diameter, whereas no abnormal inflammatory reaction was found after the subcutaneous implantation of films prepared from the same kafirin microparticles.…”

Thin TiO2 Coatings by ALD Enhance the Cell Growth on TiO2 Nanotubular and Flat Substrates

“…Therefore, to increase the bioactivity of Ti, various surface modifications on Ti have been performed, including abrasive blasting; , acid and laser etching; − and additional coating with, e.g., hydroxyapatite, silver phosphate, or calcium phosphate . Numerous studies − show a positive effect on cell growth and proliferation by the decorating of different surfaces (Ti, TiO 2 , ZrO 2 , or Mg/Sr alloy) by atomic layer deposition (ALD) with various coatings (CaCO 3 , TiO 2 , or ZnO). A study on L929 murine fibroblasts by Radtke et al reports a novel TiO 2 nanotubular/hydroxyapatite nanocomposite based on TiO 2 nanotubes (TNTs) coated by 100 ALD CaCO 3 cycles possessing optimized biocompatible properties.…”