Atividade antimicrobiana de extratos hidroalcólicos de espécies da coleção de plantas medicinais CPQBA/UNICAMP

Duarte, Marta Cristina Teixeira; Figueira, Glyn Mara; Pereira, B.; Magalhães, Pedro Melillo de; Delarmelina, Camila

doi:10.1590/s0102-695x2004000300003

Cited by 44 publications

(37 citation statements)

References 2 publications

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“…The petrol and dichloromethane crude extracts were active, but the dichloromethane was slightly more active than the petrol extract (Table I). By analyzing the MIC values obtained for the petrol and dichloromethane crude extracts (Table II), it could be concluded that, these values are lower than some values previously found in extract with antimicrobial activity (Duarte et al 2004, Virtuoso et al 2005. Based on the MIC values, extracts can have strong (0.05 to 0.5 mg.mL ˗1 ), moderate (0.6 to 1.5 mg.mL ˗1 ), or weak activity (> 1.5 mg.mL…”

Section: Resultsmentioning

confidence: 69%

Antibiotic activity of Plectranthus ornatus Codd., a Traditional Medicinal Plant

Nascimento

Albuquerque

Oliveira

et al. 2017

An. Acad. Bras. Ciênc.

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The dichloromethane extract of Plectranthus ornatus Codd., a tradicional medicinal plant, showed antibiotic activity with minimum inhibitory concentration (MIC) values of 0.4 mg.mL -1 and 100 percent of biofilm inhibition against Staphylococcus aureus strains isolated from animals with mastitis infections. Based on these antibacterial activities, in addition to ethnopharmacological reports from healing men and farmers in Brazil, an herbal soap was produced from this active extract and was tested both in vitro and in vivo. In vivo assays conducted on these herbal soaps led to results similar to those previously conducted with the active extract. These results indicated the great potential of this plant for use as an excipient by preparing herbal antibacterial soaps as an alternative veterinary medicine aimed at controlling bovine mastitis infections on small Brazilian farms.

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Section: Resultsmentioning

confidence: 69%

Antibiotic activity of Plectranthus ornatus Codd., a Traditional Medicinal Plant

Nascimento

Albuquerque

Oliveira

et al. 2017

An. Acad. Bras. Ciênc.

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“…As plantas medicinais estão dentre os produtos naturais, de grande interesse científi co devido à possibilidade de empregá-las como fi tofármacos, por proporcionarem grandes chances de obterem-se moléculas protótipos devido a sua diversidade de seus constituintes (Nascimento et al, 2000;Pessini et al, 2003;Duarte et al, 2004;Michelin et al, 2005;Lima et al, 2006).…”

Section: Introductionunclassified

Atividade antimicrobiana do extrato de Anacardium occidentale Linn. em amostras multiresistentes de Staphylococcus aureus

Silva¹,

Souza²,

Higino³

et al. 2007

Rev. bras. farmacogn.

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RESUMO:Plantas medicinais com propriedades terapêuticas são de grande relevância em todo o mundo, principalmente em países em desenvolvimento. A planta Anacardium occidentale Linn. é largamente usada na medicina tradicional na nossa região, como antidiarréico, para amigdalite, bronquites, artrites, e antiifl amatório. No presente estudo avaliou-se a ação antimicrobiana do extrato hidroalcóolico da casca do caule do cajueiro frente a amostras de Staphylococcus aureus resistentes e sensíveis à meticilina, obtidas a partir de pacientes internados do Hospital Universitário/Universidade Federal da Paraíba. A atividade antimicrobiana foi determinada pelo método de difusão em meio sólido para a determinação da Concentração Inibitória Mínima do extrato, e foi observada no total de 30 amostras, pela presença ou não do halo de inibição. Todas as amostras ensaiadas mostraram-se sensíveis à ação do extrato do cajueiro, com diâmetros dos halos de inibição variando de 10 a 20 mm, demonstrando grande efi cácia do cajueiro. Assim, o uso desta planta na nossa região pode inferir uma alternativa terapêutica efi ciente e de baixo custo, contra infecções bacterianas causadas por Staphylococcus aureus.Unitermos: Anacardiaceae, Anacardium occidentale, Staphylococcus aureus, atividade antimicrobiana.ABSTRACT: "Antimicrobial activity of the hydroalcoholic extract of Anacardium occidentale Linn. against multi-drug resistant strains of Staphylococcus aureus". Medicinal plants with therapeutical properties are of great signifi cance in the whole world, especially in developing countries. Anacardium occidentale Linn. is a plant widely used in the traditional medicine in our region against diarrhea, tonsillitis, bronchitis, arthritis, and infl ammation. In this paper, the antimicrobial activity of the hydroalcoholic extract of the cashew tree stem was evaluated against samples of meticillin-resistant and meticillin-sensible Staphylococcus aureus, attained from patients interned at Hospital Universitário/Universidade Federal da Paraíba. The antimicrobial activity was determined by the diffusion method in solid milieu to determine the Minimum Inhibitory Concentration (MIC) of the extract, and it was observed in 30 samples the presence or not of inhibition zone. All the assayed samples proved to be sensible to the activity of the extract of the cashew tree, with inhibition zones diameter of 10 to 20 mm, displaying consequently great effectiveness of the extract of the cashew tree stem. Thus, the use of this plant in our region can infer a low cost and effi cient therapeutical alternative against bacterial infections caused by Staphylococcus aureus.

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“…Essential oils present antimicrobial activity against a variety of bacteria and yeasts, including resistant species to antibiotics and antifungal agents Duarte et al, 2004;Bertini et al, 2005;Lima et al, 2006). Composition of the essential oils can vary with the climate, geographical area, seasons, soil conditions, crop period and extraction technique (Maciel et al, 2002;Bertini et al, 2005;Carvalho-Filho et al, 2006;Potzernheim et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

Preliminary study of the antimicrobial activity of Mentha x villosa Hudson essential oil, rotundifolone and its analogues

Arruda¹,

Antunes²,

Catão³

et al. 2006

Rev. bras. farmacogn.

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RESUMO: "Estudo preliminar da atividade antimicrobiana do óleo essencial de Mentha x villosa Hudson, rotundifolona e seus análogos". Os óleos essenciais apresentam atividade antimicrobiana contra uma variedade de bactérias e fungos, incluindo espécies resistentes a antibióticos e antimicóticos. Neste contexto, este trabalho objetiva a avaliação da atividade de antimicrobiana do óleo essencial de Mentha x villosa Hudson (hortelã-da-folha-miúda) -seu componente majoritário (rotundifolona) e quatro análogos sintéticos da rotundifolona (epóxi-limoneno epóxi-pulegona, epóxi-carvona e (+)-pulegona) frente a cepas padrão de Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922 Pseudomonas aeruginosa ATCC 27853, Candida albicans ATCC 76645 e uma cepa de Staphylococcus aureus meticilina -resistente -MRSA (171c) de clínica humana. Como método, foi utilizada a difusão em placas com médio sólido. Os resultados mostraram que o óleo de Mentha x villosa, rotundifolona, epóxi-limoneno e (+)-pulegona, são semelhante em função da atividade antimicrobiana para as cepas de S. aureus e C.albicans testadas. Todos os produtos apresentaram potencial antimicrobiano com atividade antibacteriana para S. aureus ATCC 25923 e atividade antifúngica para C. albicans ATCC 76645. Nenhum dos produtos apresentou atividade antimicrobiana para as cepas de E. coli ATCC 25922 e P. aeruginosa ATCC 27853, representantes das bactérias Gram negativas.Unitermos: Mentha x villosa, Labiatae, óleo essencial, rotundifolona, atividade antimicrobiana. ABSTRACT:Essential oils present antimicrobial activity against a variety of bacteria and yeasts, including species resistant to antibiotics and antifungicals. In this context, this work aims at the evaluation of the antimicrobial activity of the essential oil of Mentha x villosa Hudson ("hortelã da folha miúda"), its major component (rotundifolone) and four similar analogues of rotundifolone (limonene oxide, pulegone oxide, carvone epoxide and (+)-pulegone) against strain standards of Staphylococcus aureus ATCC 25923, E. coli ATCC 25922, Pseudomona aeruginosa ATCC 27853, Candida albicans ATCC 76645 and one strain of meticilin -resistant Staphylococcus aureus -MRSA (171c) from human clinic. The method of the diffusion in plates with solid medium was used. The results showed that the oil of Mentha x villosa, rotundifolone, limonene oxide and (+)-pulegone, are similar regarding the antimicrobial activity against the tested strains of S. aureus and C. albicans. All of the products present antimocrobial potential with antibacterial activity for S. aureus ATCC 25923 and antifungal activity for C. albicans ATCC 76645. None of the products presented antimicrobial activity for the strains of E. coli ATCC 25922 and P. aeruginosa ATCC 27853, representatives of the Gram negative bacteria.

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Atividade antimicrobiana de extratos hidroalcólicos de espécies da coleção de plantas medicinais CPQBA/UNICAMP

Cited by 44 publications

References 2 publications

Antibiotic activity of Plectranthus ornatus Codd., a Traditional Medicinal Plant

Antibiotic activity of Plectranthus ornatus Codd., a Traditional Medicinal Plant

Atividade antimicrobiana do extrato de Anacardium occidentale Linn. em amostras multiresistentes de Staphylococcus aureus

Preliminary study of the antimicrobial activity of Mentha x villosa Hudson essential oil, rotundifolone and its analogues

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