Asystole during combination chemotherapy for non-Hodgkin's lymphoma: the acute tumor lysis syndrome

Jm, van der Klooster; He, V.; Jl, van Saase; Af, Grootendorst

doi:10.1016/s0300-2977(99)00124-2

Cited by 22 publications

(3 citation statements)

References 17 publications

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“…Extra care is required in the early stage of treatment as tumor lysis may lead to cardiac complications including rupture of the heart or asystole [17].…”

Section: Discussionmentioning

confidence: 99%

Cardiac Mass and Hypertrophic Cardiomyopathy as Aggressive Presentation of Primary Cardiac Lymphoma: A Case Report

Haran¹,

Enakpene²,

Lodha³

2012

JCT

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Primary cardiac lymphoma is very rare. This disease occurs mainly in immunocompromised patients and rarely in the immunocompetent. With the advent of echocardiogram, computed tomography and magnetic resonance imaging, more cases are being diagnosed ante-mortem although the prognosis still remains poor. These cardiac tumors provide unique diagnostic and therapeutic challenges. We present an interesting case of primary cardiac lymphoma diagnosed antemortem in an 81 year old immunocompetent female presenting as a large mass in the right atrium, right ventricle and encasing the right coronary artery; and asymmetric left ventricular hypertrophy, a variant of hypertrophic cardiomyopathy. Patient responded very well to chemotherapy with subsequent regression of the cardiac mass and ventricular hypertrophy.

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“…Extra care is required in the early stage of treatment as tumor lysis may lead to cardiac complications including rupture of the heart or asystole [17].…”

Section: Discussionmentioning

confidence: 99%

Cardiac Mass and Hypertrophic Cardiomyopathy as Aggressive Presentation of Primary Cardiac Lymphoma: A Case Report

Haran¹,

Enakpene²,

Lodha³

2012

JCT

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“…[2][3][4][5][6][8][9][10] It is less often reported in acute myeloid leukemia (AML) and other hematologic malignancies. 7,10-12 As newer, more effective therapies became available for a wide-range of malignancies, there has been an increase in TLS cases described in the literature.…”

Section: Discussionmentioning

confidence: 99%

Spontaneous tumor lysis syndrome in acute myeloid leukemia: Two cases and a review of the literature

Riccio¹,

Mato²,

Olson³

et al. 2006

Cancer Biology & Therapy

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KEy wORdSspontaneous tumor lysis syndrome, acute spontaneous tumor lysis syndrome, urate nephropathy, tumor lysis syndrome, acute myeloid leukemia, acute renal failure, hyperuricemia ABStRActSpontaneous tumor lysis syndrome (TLS) is a constellation of electrolyte abnormalities and acute renal failure, which occurs in the setting of rapid cell turnover prior to the administration of cytotoxic chemotherapy. While spontaneous TLS is well described in patients with Burkitt's lymphoma, it is thought to occur less commonly in other hematologic malignancies. We present two cases of spontaneous TLS in patients with newly diagnosed acute myeloid leukemia (AML) followed by a review of the literature in this field.

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“…Plasma concentrations greater than 6.5 mEq/L may induce muscle weakness, paralysis, electrocardiogram (ECG) changes, cardiac arrhythmias, or sudden death. 1,7 As with any sample, pseudohyperkalemia can result from hemolyzed blood samples in patients with an elevated white blood cell (WBC) or platelet count. ECG changes such as peaked T-waves and QRS widening are absent in these patients.…”

Section: Hyperkalemiamentioning

confidence: 99%

Pediatric Tumor Lysis Syndrome

Bickert

Reilly

2004

Journal of Pharmacy Practice

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Patients with a high tumor burden may develop tumor lysis syndrome. Tumor lysis syndrome consists of at least 2 metabolic abnormalities, which may include hyperkalemia, hyperphosphatemia, or hyperuricemia. The goal of standard therapy is to prevent tumor lysis syndrome. Prophylactic therapy includes hydration, alkalinization, and treatment to lower uric acid with either allopurinol or rasburicase. Other metabolic abnormalities are treated as they occur.

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Asystole during combination chemotherapy for non-Hodgkin's lymphoma: the acute tumor lysis syndrome

Cited by 22 publications

References 17 publications

Cardiac Mass and Hypertrophic Cardiomyopathy as Aggressive Presentation of Primary Cardiac Lymphoma: A Case Report

Cardiac Mass and Hypertrophic Cardiomyopathy as Aggressive Presentation of Primary Cardiac Lymphoma: A Case Report

Spontaneous tumor lysis syndrome in acute myeloid leukemia: Two cases and a review of the literature

Pediatric Tumor Lysis Syndrome

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