Asymptomatic SARS‐CoV‐2 infected case with viral detection positive in stool but negative in nasopharyngeal samples lasts for 42 days

Jiang, Xuejun; Luo, Moulun; Zou, Zhen; Wang, Xu; Chen, Chengzhi; Qiu, Jingfu

doi:10.1002/jmv.25941

Cited by 119 publications

(119 citation statements)

References 9 publications

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“…WANGET AL. tested for positive in feces, but not in nasopharyngeal swabs, suggesting the possibility of transmission via fecal-oral route 14. 5 | THOUGHTS ON THE INFECTIVITY OF ASYMPTOMATIC CASES IN REAL WORLDAlthough grooming evidence suggest possible transmission of SARS-CoV-2 from asymptomatic cases, the World Health Organization declared that coronavirus has relatively low risk transmitted through asymptomatic cases from past experience in the middle east respiratory syndrome.…”

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confidence: 99%

Asymptomatic cases with SARS‐CoV‐2 infection

Wang

Kang

et al. 2020

Journal of Medical Virology

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On 31 March 2020, Chinese Health Authorization announced that numbers of asymptomatic cases with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection will be made to the public daily. This was a very important step since different counties have different capacities for the detection of SARS-CoV-2 infection and control strategy for the Coronavirus Disease 2019 outbreak. We summarized the characteristics of asymptomatic SARS-CoV-2 infections and the transmission potential of asymptomatic cases. Then we provided guidelines for the management of asymptomatic cases through quarantine and nucleic acid/serology tests.

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confidence: 99%

Asymptomatic cases with SARS‐CoV‐2 infection

Wang

Kang

et al. 2020

Journal of Medical Virology

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“…Respiratory and contact routes are proven transmission mechanisms for COVID-19 infection. However, in a recent study, SARS-CoV-2 RNA was detected in the fecal samples of COVID-19 patients, indicating the possibility of transmission via the fecal-oral route (Jiang et al, 2020;Xu et al, 2020). In our study, respiratory and contact should be considered as the two main transmission mechanisms responsible for this cluster of infections.…”

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confidence: 54%

A familial cluster of COVID-19 infection in a northern Chinese region

Sun

Liu²,

Zhang

et al. 2020

Preprint

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Background Currently, coronavirus disease 2019 (COVID-19) has spread worldwide and become a global health concern. Here, we report a familial cluster of COVID-19 infection in a northern Chinese region and share our local experience. Methods A familial cluster of six patients infected with severe acute respiratory coronavirus 2 (SARS-CoV-2) was included for analysis. The demographic data, clinical features, laboratory examinations, and epidemiological characteristics of enrolled cases were collected and analyzed. Results Two family members (Cases 1 and 2) had Hubei exposure history and were admitted to the hospital with a confirmed diagnosis of COVID-19; eight familial members who had contact with them during the incubation period were isolated in a hospital. Finally, the condition of four members (Cases 3, 4, 5, and 6) was as follows. Case 3 had negative SARS-CoV-2 RT-PCR results but was suspected to have COVID-19 because of radiographic abnormalities. Cases 4 and 5 developed COVID-19. Due to positive SARS-CoV-2 RT-PCR results, Case 6 was considered an asymptomatic carrier. In addition, four close contacts did not have evidence of SARS-CoV-2 infection. Conclusions Our findings suggest that COVID-19 has infectivity during the incubation period and preventive quarantine is effective for controlling an outbreak of COVID-19 infection.

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“…Respiratory virus (pharyngeal virus) shedding has been found in asymptomatic infections, confirming their potential ability to spread [16]. Jiang et al [17] suggested that the faecal-oral route might be another way of transmission for asymptomatic infections. In Table 3.…”

Section: Discussionmentioning

confidence: 97%

Safety considerations during return to work in the context of stable COVID-19 epidemic control: an analysis of health screening results of all returned staff from a hospital

et al. 2020

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In March 2020, China had periodically controlled the coronavirus disease-19 (COVID-19) epidemic. We reported the results of health screening for COVID-19 among returned staff of a hospital and conducted a summary analysis to provide valuable experience for curbing the COVID-19 epidemic and rebound. In total, 4729 returned staff from Zhongnan Hospital of Wuhan University, Wuhan, China were examined for COVID-19, and the basic information, radiology and laboratory test results were obtained and systematically analysed. Among the 4729 employees, medical staff (62.93%) and rear-service personnel (30.73%) were the majority. The results of the first physical examination showed that 4557 (96.36%) were normal, 172 (3.64%) had abnormal radiological or laboratory test results. After reexamination and evaluation, four were at high risk (asymptomatic infections) and were scheduled to transfer to a designated hospital, and three were at low risk (infectivity could not be determined) and were scheduled for home isolation observation. Close contacts were tracked and managed by the Center for Disease Control and Prevention (CDC) in China. Asymptomatic infections are a major risk factor for returning to work. Extensive health screening combined with multiple detection methods helps to identify asymptomatic infections early, which is an important guarantee in the process of returning to work.

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Asymptomatic SARS‐CoV‐2 infected case with viral detection positive in stool but negative in nasopharyngeal samples lasts for 42 days

Cited by 119 publications

References 9 publications

Asymptomatic cases with SARS‐CoV‐2 infection

Asymptomatic cases with SARS‐CoV‐2 infection

A familial cluster of COVID-19 infection in a northern Chinese region

Safety considerations during return to work in the context of stable COVID-19 epidemic control: an analysis of health screening results of all returned staff from a hospital

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