Associations of number of teeth with risks for all‐cause mortality and cause‐specific mortality in middle‐aged and elderly men in the northern part of Japan: the Iwate‐KENCO study

Abstract

The number of teeth is an important predictive factor for mortality among middle-aged Japanese men.

Is poor oral health a risk marker for incident cardiovascular disease hospitalisation and all-cause mortality? Findings from 172 630 participants from the prospective 45 and Up Study

“…To the best of our knowledge, the current study, with over 170 000 participants, is larger than any previous prospective study of oral health and CVD,13 15 16 and is the only one that looks at the association between severity of oral health problems and the risk of a range of non-fatal CVD outcomes and all-cause mortality within the same cohort. Previous epidemiologic studies varied in the oral health exposures (periodontitis (self-reported, clinical or radiographic), gingivitis, tooth loss classification, bone loss, pocket depth) and in the definition of CVD outcomes;3 13 28–30 therefore, the associations have not been consistently replicated.…”

“…13–15 17 28 The Iwate-KENCO study,15 among men aged 40–79 years free from CVD at baseline, which used similar measures of tooth loss, reported higher risk of all-cause mortality in those with none of their natural teeth left, compared with those reporting ≥20 natural teeth left (HR 1.46 (1.12 to 1.91) when adjusted for age and 1.28 (0.97 to 1.68) when multivariate adjusted). The Scottish cohort study4 of over 12 000 people with linked mortality showed increased risk of all-cause mortality and CVD mortality (HRs 1.30 (1.12 to 1.50) and 1.49 (1.16 to 1.92), respectively) among those with none of their natural teeth left compared with participants with natural teeth only.…”

Periodontal Disease and Incident Lung Cancer Risk: A Meta‐Analysis of Cohort Studies

“…Five cohort studies were eventually included in the meta‐analysis 7,16,17,19,26 . Reasons for exclusion of the seven excluded studies were: 1) lack of data (n = 3); 27–29 2) inappropriate study design (case‐control study, n = 1; intervention study, n = 1); 11 , 30 and 3) inappropriate exposure (tooth loss; n = 2) 8 , 18 Figure 1. illustrates the study selection process.…”

Association between the number of teeth and hypertension in a study based on 13,561 participants

“…Edentulous rates are a crucial indicator of the operation of a country's oral healthcare system; therefore, it is imperative to monitor its occurrence . Several studies have shown that tooth loss is a predictor of cardiovascular mortality and could be a useful risk indicator for atherosclerosis …”

“…11 Edentulous rates are a crucial indicator of the operation of a country's oral healthcare system; therefore, it is imperative to monitor its occurrence. 12 Several studies have shown that tooth loss is a predictor of cardiovascular mortality [13][14][15][16] and could be a useful risk indicator for atherosclerosis. 17 Epidemiological studies in the dental and medical area have supported the potential association between increased blood pressure, hypertension, and periodontitis through the inflammation pathway.…”