Association of gingival crevicular fluid and serum intracytoplasmic enzyme levels in periodontally healthy homozygous (major) β‐thalassemia patients

Abstract

Elevated values of LDH, ALT and AST in serum do not constitute a confounding factor in GCF measurements of the respective enzymes.

The Association Between Thalassemia Major and Periodontal Health

“…Oral health problems in patients with TM are mostly related to varying degrees of facial deformities, malocclusions, or dental arch dimensions 14‐16 . To date, there are limited data available on the periodontal health status of patients with TM 17‐19 . It was hypothesized that TM may cause increased levels of inflammatory cytokines in biofluids, particularly when there is accompanying gingival inflammation, which in turn may modify the clinical signs of both chronic diseases.…”

“…[14][15][16] To date, there are limited data available on the periodontal health status of patients with TM. [17][18][19] It was hypothesized that TM may cause increased levels of inflammatory cytokines in biofluids, particularly when there is accompanying gingival inflammation, which in turn may modify the clinical signs of both chronic diseases. Therefore, the aim of the present study is to investigate the local and systemic levels of soluble RANKL (sRANKL), OPG, APRIL, BAFF, IL-6, and IL-8 comparatively in patients with TM with or without gingivitis.…”

Host Derived Enzymes in Gingival Crevicular Fluid as a Periodontal Diagnostic Biomarker-Part 2: Review

“…DPP inhibitörleri ise özellikle diyabet, onkoloji ve hematolojide terapö-tik bir potansiyele sahiptir. 9 DPP'ler, kollajeni Kaner ve ark., 38 Buchmann ve ark., 39 Hernández ve ark., 40 Marcaccini ve ark., 41 Laktat dehidrojenaz Perinetti ve ark., 42 Tsalikis ve ark., 44 Lamster ve ark. 45 Arilsülfataz Lamster ve ark.…”

“…Bu nedenle, hastalığın aktivitesinin potansiyel bir belirteci olarak incelenmiştir. 44 LDH anaerobik glikolitik yolun sitoplazmik bir enzimidir. 45 İnflame diş etinin anaerobik glikoliz karakteristiğindeki artışı yansıtır.…”

Quantification of Lactate-Dehydrogenase and Cell Viability in Postmortem Human Dental Pulp

“…LDH presence in serum and gingival cervical fluid has been used for establishing periodontal disease status (13). Histochemistry has been used for studying LDH in dental pulp when evaluating the toxic effect of several materials normally used in dental practice (14 -17).…”