Association between vitiligo lesions and acute chikungunya infection: is there a causal relationship?

Farias, Luís Arthur Brasil Gadelha; Bezerra, Kalina Ribeiro Fontenele; Albuquerque, Melina Maria de Sousa; Neto, Roberto da Justa Pires; Filho, José Gomes Bezerra

doi:10.1590/0037-8682-0238-2019

Cited by 2 publications

(1 citation statement)

References 8 publications

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“…Cheilitis, skin and mouth ulcers, crusted lesions, vesiculobullous lesions (frequently observed in children and neonates), skin peeling, xerosis, papules, erythema nodosum, and vasculitis-like lesions have also been reported [42][43][44] . CHIKV may also act as a trigger for vitiligo and other autoimmune diseases 45,46 .…”

Section: Cutaneous Manifestationsmentioning

confidence: 99%

Extra-articular Manifestations of Chikungunya

Oliveira,

Nogueira,

Amaral

et al. 2023

Rev. Soc. Bras. Med. Trop.

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Chikungunya fever (CHIK) is a neglected tropical disease associated with chronic arthritis. CHIK is usually a self-limiting condition; however, extra-articular manifestations present as atypical illness in a minority of patients. These atypical features may mimic other conditions and potentially distract physicians from the true diagnosis. This review analyzes the evidence of many unusual extra-articular manifestations reported in cases of CHIK. Depending on the affected system, these unusual manifestations include encephalitis, myocarditis, acute interstitial nephritis, cutaneous manifestations, acute anterior uveitis, abdominal pain, and depression. In addition, coinfections and comorbidities may cause atypical illness and obscure the diagnosis. Further studies are required to clarify the pathophysiology and natural history of CHIK, as it remains a burdening condition. Exploring its atypical symptoms may be the missing scientific piece of this puzzle.

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