Association between temporomandibular disorders and anxiety: A systematic review

Santos, Erick Alves dos; Peinado, Beatriz Rodrigues Risuenho; Frazão, Déborah Ribeiro; Né, Yago Gecy de Sousa; Fagundes, Nathália Carolina Fernandes; Magno, Marcela Baraúna; Maia, Lucianne Cople; Lima, Rafael Rodrigues; Souza-Rodrigues, Renata Duarte de

doi:10.3389/fpsyt.2022.990430

Cited by 7 publications

(1 citation statement)

References 54 publications

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“…The etiology of TMD is still controversial. However, studies show that its origin is multifactorial, including biopsychosocial factors [ 7 , 8 ]. Risk factors that exert influence for a few years before the manifestation of TMD signs and symptoms (predisponents) must be taken into consideration, as well as those that act for the condition to develop (initiators) and those that cause the continuation of TMD (perpetuators), making it difficult for the outcome of the treatment [ 9 , 10 ].…”

Section: Introductionmentioning

confidence: 99%

Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells

Silva

Melo

Ferreira

et al. 2023

JFB

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Temporomandibular disorder (TMD) is an umbrella term used to describe various conditions that affect temporomandibular joints, masticatory muscles, and associated structures. Although the most conservative and least invasive treatment is preferable, more invasive therapies should be employed to refractory patients. Tissue engineering has been presented as a promising therapy. Our study aimed to investigate trends and point out future research directions on TMD and stem cells. A comprehensive search was carried out in the Web of Science Core Collection (WoS-CC) in October 2022. The bibliometric parameters were analyzed through descriptive statistics and graphical mapping. Thus, 125 papers, published between 1992 and 2022 in 65 journals, were selected. The period with the highest number of publications and citations was between 2012 and 2022. China has produced the most publications on the subject. The most frequently used keywords were “cartilage”, “temporomandibular joint”, “mesenchymal stem cells”, and “osteoarthritis”. Moreover, the primary type of study was in vivo. It was noticed that using stem cells to improve temporomandibular joint repair and regeneration is a significant subject of investigation. Nonetheless, a greater understanding of the biological interaction and the benefits of using these cells in patients with TMD is required.

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Section: Introductionmentioning

confidence: 99%

Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells

Silva

Melo

Ferreira

et al. 2023

JFB

Self Cite

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Causal relationship between psychiatric traits and temporomandibular disorders: a bidirectional two-sample Mendelian randomization study

Xiang,

Song,

Liang

et al. 2023

Clin Oral Invest

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Objectives This study was to investigate the causal relationship between temporomandibular disorders (TMD) and psychiatric disorders by Mendelian randomization (MR) analysis. Materials and methods A two-sample bidirectional MR analysis was adopted to systematically explore the causal relationship between TMD and eight psychiatric traits, including anxiety disorder (AD), panic disorder (PD), major depressive disorder (MDD), neuroticism, attention deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD), bipolar disorder (BIP), and schizophrenia (SCZ). Inverse variance weighted (IVW), weighted median, and MR-Egger regression were used in my study. Furthermore, we also performed three sensitivity analyses to illustrate the reliability of the analysis. Results Two psychiatric traits have risk effects on TMD: PD (OR = 1.118, 95% CI: 1.047–1.194, P = 8.161 × 10−4, MDD (OR = 1.961, 95% CI: 1.450–2.653, P = 1.230 × 10−5). Despite not surpassing the strict Bonferroni correction applied (P > 0.00625), we could think that there was a suggestive causal effect of neuroticism and SCZ increasing the risk of TMD. On the reverse MR analysis, we found no significant evidence of causal effects of TMD on these psychiatric traits. Except for heterogeneity in the causal analysis for SCZ on TMD, no heterogeneity and horizontal pleiotropy were detected in the other analyses. Conclusions Our two-sample MR study has provided further evidence of PD and MDD being related to a higher risk of TMD. Clinical relevance These findings highlight the importance of closely monitoring mental traits during future TMD treatments to prevent an increased risk of TMD.

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Prevalence and associations of temporomandibular disorders in older Brazilian adults

et al. 2023

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ObjectiveThe objective of the study was to estimate the prevalence of temporomandibular disorders (TMD) and describe associations in a representative sample of community‐dwelling older Brazilian adults.BackgroundTMD cause recurrent or chronic pain and dysfunction with substantial impacts on quality of life, but little is known of their occurrence and associated factors among older adults.Materials and MethodsThis was a cross‐sectional study using data from the second wave of the Brazilian Longitudinal Study of Aging, a nationally representative sample of older Brazilian adults aged 50 or older. The presence of temporomandibular disorder symptoms was measured by the Fonseca Anamnestic Index. Independent variables included sociodemographic characteristics, general health conditions and self‐reported oral health measures. The association between the independent variables and TMD symptoms was evaluated using logistic regression models.ResultsComplete information for the variables of interest was available for 9391 individuals. The overall prevalence of TMD symptoms was 18.0% (95% CI 14.4–22.1). Relative to older adults aged 50–59 those in all age categories had lower odds of TMD symptoms. Individuals with depression, pain, sleep problems and self‐reported poor general health had higher odds of reporting TMD symptoms. None of the oral health measures were related to TMD.ConclusionThe prevalence of TMD symptoms among Brazilian older adults is associated with demographic and general health conditions, but not with dentition status.

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Association between temporomandibular disorders and anxiety: A systematic review

Cited by 7 publications

References 54 publications

Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells

Global Trends and Future Research Directions for Temporomandibular Disorders and Stem Cells

Causal relationship between psychiatric traits and temporomandibular disorders: a bidirectional two-sample Mendelian randomization study

Prevalence and associations of temporomandibular disorders in older Brazilian adults

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