Association between subclinical hypothyroidism and severe diabetic retinopathy in Korean patients with type 2 diabetes

Kim, Bo-Yeon; Kim, Chul-Hee; Jung, Chan‐Hee; Mok, Ji‐Oh; Suh, Kyoil; Kang, Suk‐Ku

doi:10.1507/endocrj.ej11-0199

Cited by 59 publications

(70 citation statements)

References 26 publications

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“…In the present study and the Korean study, diabetic nephropathy was defined according to the American Diabetes Association criteria, with reported diabetic nephropathy prevalence of 7.0% and 6.4% [12], respectively. However, in the Chinese study, nephropathy was defined using creatinine and albuminuria grade [14], and the prevalence of diabetic nephropathy was considerably higher (48.6%).…”

Section: Discussionmentioning

confidence: 82%

“…However, in the Chinese study, nephropathy was defined using creatinine and albuminuria grade [14], and the prevalence of diabetic nephropathy was considerably higher (48.6%). tion between SCH and diabetic retinopathy were controversial; 3 of the studies showed an association [12,17], while a study conducted in Spain did not [18]. To the best of our knowledge, no study to date has investigated the association between SCH and diabetic neuropathy.…”

Section: Discussionmentioning

confidence: 99%

“…There are only a few reports regarding an association between SCH and diabetic nephropathy [12][13][14]. already taking anti-hypertensive drugs.…”

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confidence: 99%

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Association between subclinical hypothyroidism and diabetic nephropathy in patients with type 2 diabetes mellitus

et al. 2014

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Section: Discussionmentioning

confidence: 82%

Section: Discussionmentioning

confidence: 99%

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Association between subclinical hypothyroidism and diabetic nephropathy in patients with type 2 diabetes mellitus

et al. 2014

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“…They mentioned several mechanisms for this involvement like dyslipidemia, insulin resistance etc. 9 Yang GR et al in a case control study found that the prevalence of Subclinical hypothyroidism in the proliferative diabetic retinopathy group (51/187, 27.3%) was higher than that in the non-proliferative diabetic retinopathy group (32/184, 17.4%). In their study, they had done a logistic regression analysis to identify an independent relationship between SCH and PDR.…”

Section: Resultsmentioning

confidence: 95%

A study on relationship between severity of diabetic retinopathy and subclinical hypothyroidism

Borooah

Phukan

2017

Int J Res Med Sci

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Background: Subclinical hypothyroidism (SCH) is defined as an asymptomatic condition characterized by normal serum levels of free thyroxine and elevated serum concentration of thyrotropin (>4.0µIU/ml). Association between diabetic retinopathy and SCH is unclear. Aim was to study the relationship between severity of diabetic retinopathy and SCH in patients of diabetic retinopathy with type 2 diabetes mellitus.Methods: 120 patients of diabetic retinopathy with known type 2 diabetes mellitus were taken and categorized them according to severity of diabetic retinopathy as per ETDRS classification. Serum thyrotropin (TSH) and free thyroxine (FT4) concentration were measured in all 120 patients. Patients with normal TSH and FT4 values are euthyroid patients and those with normal FT4 but TSH value >4µIU/ml are considered as having subclinical hypothyroidism. Severity of diabetic retinopathy is compared between the euthyroid and subclinical hypothyroid group.Results: Out of the 120 patients included in the study, 72 (60%) were male and 48 (40%) were female. 97 patients (80.83%) were Euthyroid and 23 patients (19.17%) had subclinical hypothyroidism. It was observed that prevalence of more severe form of diabetic retinopathy (severe NPDR and PDR) was higher in SCH group as compared to euthyroid group. Severity of diabetic retinopathy was compared with serum TSH level and it was seen that severity of diabetic retinopathy significantly increases with increase in serum TSH value.Conclusions: Patients with SCH had more severe form of diabetic retinopathy as compared to patients with euthyroidism. Severity of diabetic retinopathy significantly increases with increase in serum TSH value.

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“…It was with a great interest that we have read the article entitled "Association between subclinical hypothyroidism and severe diabetic retinopathy in Korean patients with type 2 diabetes" by Bo-Yeon Kim et al [1] published recently in this journal. I was moved by the authors' efforts for examining whether subclinical hypothyroidism (SCH) was associated with diabetic retinopathy or nephropathy in Korean patients with type 2 diabetes.…”

Section: Dear Sir;mentioning

confidence: 99%

Comment on: “Association between subclinical hypothyroidism and severe diabetic retinopathy in Korean patients with type 2 diabetes” [Letter to the Editor]

Gao

Yuan

2011

Endocr J

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Association between subclinical hypothyroidism and severe diabetic retinopathy in Korean patients with type 2 diabetes

Cited by 59 publications

References 26 publications

Association between subclinical hypothyroidism and diabetic nephropathy in patients with type 2 diabetes mellitus

Association between subclinical hypothyroidism and diabetic nephropathy in patients with type 2 diabetes mellitus

A study on relationship between severity of diabetic retinopathy and subclinical hypothyroidism

Comment on: “Association between subclinical hypothyroidism and severe diabetic retinopathy in Korean patients with type 2 diabetes” [Letter to the Editor]

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