Comment on: “Association between subclinical hypothyroidism and severe diabetic retinopathy in Korean patients with type 2 diabetes” [Letter to the Editor]

Gao, Zhen-hua; Yuan, Ruyu; Li, Guangping

doi:10.1507/endocrj.ej11-0281

Cited by 2 publications

(2 citation statements)

References 6 publications

(3 reference statements)

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“…1,2 Diabetics will lead to high glucose condition as well as a variety of complications, including cardiovascular disease, nerve damage (neuropathy), kidney damage (kidney disease), eye damage (retinopathy), hearing impairment, dementia, and especial the delayed wound healing which is one of the most serious complications of diabetes impaired wound healing. [3][4][5][6][7][8][9] Severe diabetic wounds could lead to amputation. 10 Diabetes can be divided into four main types: Type Ⅰ diabetes is caused by the autoimmune be destroyed of β-cells in the pancreas, eventually leading to reduction of insulin production; 11,12 Type Ⅱ diabetes is closely associated with insulin resistance and subsequent decompensation of pancreatic β-cells (including pancreatic β-cell mass loss and β-cell dysfunction); 13 Gestational diabetes occurs during pregnancy and causes glucose intolerance; 14 other diabetes are resulted by specific genetic defects of beta-cell function, illness of the pancreas, drugs or chemicals, etc.…”

Section: Introductionmentioning

confidence: 99%

<p>Potential Applications of Nanomaterials and Technology for Diabetic Wound Healing</p>

Bai¹,

Han²,

Dong³

et al. 2020

IJN

146

114

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Diabetic wound shows delayed and incomplete healing processes, which in turn exposes patients to an environment with a high risk of infection. This article has summarized current developments of nanoparticles/hydrogels and nanotechnology used for promoting the wound healing process in either diabetic animal models or patients with diabetes mellitus. These nanoparticles/hydrogels promote diabetic wound healing by loading bioactive molecules (such as growth factors, genes, proteins/peptides, stem cells/exosomes, etc.) and nonbioactive substances (metal ions, oxygen, nitric oxide, etc.). Among them, smart hydrogels (a very promising method for loading many types of bioactive components) are currently favored by researchers. In addition, nanoparticles/hydrogels can be combined with some technology (including PTT, LBL self-assembly technique and 3D-printing technology) to treat diabetic wound repair. By reviewing the recent literatures, we also proposed new strategies for improving multifunctional treatment of diabetic wounds in the future.

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Section: Introductionmentioning

confidence: 99%

<p>Potential Applications of Nanomaterials and Technology for Diabetic Wound Healing</p>

Bai¹,

Han²,

Dong³

et al. 2020

IJN

146

114

View full text Add to dashboard Cite

show abstract

“…En tal un estudio muestra que los pacientes con DT2 y valores incrementados de TSH presentan mayor prevalencia (29) de nefropatía diabética . Así mismo, estudios en población coreana con DT2, existe una ligera asociación entre (30) hipotiroidismo subclínico y retinopatía diabética severa . Nuestros resultados también mostraron asociación entre cáncer y complicación microvascular.…”

Section: Discussionunclassified

Magnitud y Factores asociados a complicaciones de diabetes tipo 2: Análisis de un Sistema de Vigilancia de Diabetes Mellitus

Cornetero-Muro

Hilario-Huapaya²,

Inolopú-Cucche

et al. 2021

Rev. Cuerpo Med. HNAAA

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Introducción: Las complicaciones por diabetes tipo 2 (DT2) están incrementando la demanda de servicios especializados en la Seguridad Social Peruana por lo que se torna necesario determinar la magnitud y factores asociados a complicación crónica por DT2 en esta población. Material y Métodos: Estudio transversal-analítico basado en 7875 registros de pacientes con DT2 ≥ 18 años atendidos por consulta externa durante 2016-2017 y notificados en el Sistema de Vigilancia de Diabetes Mellitus de EsSalud. Se evaluaron variables sociodemográficas, clínicas y de comorbilidad mediante un análisis bivariado y un modelo de regresión de Poisson con varianza robusta para determinar la razón de prevalencia a complicación crónica por DT2. Resultados: La complicación microvascular de DT2 estuvo asociado a sexo masculino (RP=1,25; 95%IC: 1,10-1,42; p<0,01), HbA1c>9,0% (RP=1,25; 95%IC: 1,08-1,46; p<0,01), hipertensión arterial (RP=1,30; 95%IC: 1,14-1,49; p<0,01), anemia (RP=1,57; 95%IC: 1,31-1,88; p<0,01), enfermedad tiroidea (RP=1,48; 95%IC: 1,07-2,03; p=0,02), cáncer (RP=1,70; 95%IC: 1,26-2,30; p<0,01) e hígado graso (RP=1,78; 95%IC: 1,28-2,48; p<0,01). El recibir educación para el autocuidado de DT2 mostró asociación negativa con complicación microvascular (RP=0,84; 95%IC: 0,73-0,96; p<0,01). La complicación macrovascular de DT2 estuvo asociado a sexo masculino (RP=1,52; 95%IC: 1,21-1,91; p<0,01), hipertensión arterial (RP=2,72; 95%IC: 1,90-3,91; p<0,01), anemia (RP=1,98; 95%IC: 1,33-2,95; p<0,01) e hígado graso (RP=1,92; 95%IC: 1,03-3,62; p=0,04), mientras que la educación en DT2 mostró asociación negativa (RP=0,47; 95%IC: 0,36-0,61; p<0,01). Conclusiones: La educación en DT2 mostró asociación consistentemente con ausencia de complicación micro y macrovascular, sugiriendo ser un importante factor preventivo. Consideramos necesario evaluar el impacto de la educación mediante diseños apropiados.

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Comment on: “Association between subclinical hypothyroidism and severe diabetic retinopathy in Korean patients with type 2 diabetes” [Letter to the Editor]

Cited by 2 publications

References 6 publications

<p>Potential Applications of Nanomaterials and Technology for Diabetic Wound Healing</p>

<p>Potential Applications of Nanomaterials and Technology for Diabetic Wound Healing</p>

Magnitud y Factores asociados a complicaciones de diabetes tipo 2: Análisis de un Sistema de Vigilancia de Diabetes Mellitus

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