Associated Factors of Brachial‐Ankle Pulse Wave Velocity in Hypertensive Patients Aged 80 and Over

Telemetric Ambulatory Arterial Stiffness Index, a Predictor of Cardio–Cerebro–Vascular Mortality, is Associated with Aortic Stiffness‐Determining Factors

“…The actual relationship between AASI and arterial stiffness remains unclear. The structural properties of the arterial wall, especially the concentration of collagen and elastin as well as the ratio of collagen/elastin, are important determining factors of vascular stiffness , which play a significant role in the pathogenesis of cerebro–vascular disease and should not change with BP fluctuations over 24 h. However, there has been no study investigating the relationships between AASI and arterial structural components (wall composition) presumably due to difficulty in harvesting human vascular samples.…”

“…Arterial stiffness is universally acknowledged as an important risk factor and independent predictor of cardio–cerebro–vascular events . Decreased elasticity of the arterial wall is implicated in the development of hypertension and increases the risk of cardiovascular mortality and fatal strokes . Cerebral and carotid arteries remodeling including changes in composition and structure of the vascular wall play an important role in the development of various cerebro–vascular diseases .…”