Associated Factors for Relapse in Opioid Addicts undergoing Therapy

Hassan, Nurulhuda Mat; Daud, Nadwah; Aziz, Abdul; Mat, Khairi Che

doi:10.5958/0974-360x.2018.00503.6

Cited by 4 publications

(3 citation statements)

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“…Relapse is a multifactorial outcome ( 44 ), which has been proven to be correlated with factors, such as marital status, living status, relationship with family, and drug use behavior ( 12 , 16 , 45 , 46 ). This study implied that these factors were influential for participants who completed the 6-month consecutive MMT.…”

Section: Discussionmentioning

confidence: 99%

The risk assessment of relapse among newly enrolled participants in methadone maintenance treatment: A group-LASSO based Bayesian network study

Tang

Fan

Wang

et al. 2023

Front. Public Health

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BackgroundRelapse is a great barrier to improving the effectiveness of methadone maintenance treatment (MMT). Participants with different treatment durations could vary in their compliance with MMT, which may lead to different levels of relapse risk. This study aims to identify the risk factors for relapse and assess the relapse risk of MMT participants of different treatment durations.MethodThis retrospective study used data collected from seven MMT clinics in Guangdong Province, China, from January 2010 to April 2017. Newly enrolled participants who received 6 (n = 903) and 12 (n = 710) months of consecutive treatment with complete data were included. We selected significant risk factors for relapse through the group lasso regression and then incorporated them into Bayesian networks to reveal relationships between factors and predict the relapse risk.ResultsThe results showed that participants who received 6-month treatment had a lower relapse rate (32.0%) than those of 12-month treatment (39.0%, P < 0.05). Factors including personal living status and daily methadone dose were only influential to those who received the 6-month treatment. However, age, age at the initial drug use, HIV infection status, sexual behaviors, and continuous treatment days were common factors of both durations. The highest relapse risk for those after the 6-month treatment was inferred as 66.7% while that of the 12-month treatment was 83.3%. Farmers and those who have high accessibility to MMT services may require additional attention.ConclusionIt is necessary to implement targeted interventions and education based on the treatment durations of participants to decrease the relapse rate. Meanwhile, those about HIV/sexually transmitted infection prevention and anti-narcotics should be held in the whole process.

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Section: Discussionmentioning

confidence: 99%

The risk assessment of relapse among newly enrolled participants in methadone maintenance treatment: A group-LASSO based Bayesian network study

Tang

Fan

Wang

et al. 2023

Front. Public Health

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“…Petit et al (8) 2017 Cross Sectional Penyebab kekambuhan antara lain keinginan menggunakan selama detoksifikasi, depresi, kecemasan. Batool et al (21) 2017 Cross Sectional Alasan kembali menyalahgunakan narkoba antara lain karena hubungan dengan sesama mantan pecandu, reaksi negatif dari keluarga, ketidakmampuan mengelola keinginan dan tekanan pekerjaan. Hassan, Daud, Aziz, dan Mat (20) 2018 Cross Sectional Faktor yang mempengaruhi kekambuhan antara lain tujuan melakukan pengobatan/terapi/rehabilitasi, durasi pengobatan/terapi/rehabilitasi, durasi penggunaan narkoba.…”

Section: Hasilunclassified

“…(20) Pelaksanaan rehabilitasi yang tidak maksimal juga menjadi pengambat seseorang gagal dalam pengobatan sehingga terjadi kekambuhan. (21) Ditemukan keadaan bahwa keinginan secara sadar untuk kembali menggunakan NAPZA menjadi penyebab paling kuat untuk terjadinya kekambuhan. (10,19) Beberapa keinginan kembali untuk menyalahgunakan NAPZA beralasan karena stress.…”

Section: Pembahasanunclassified

Faktor Penyebab Kekambuhan pada Mantan Penyalahguna NAPZA

Susila

Daulima

2020

JPKSF

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Misuse of Narcotics, Psychotropic and Other Addictive Substances is still a problem in the community. International drug abuse has increased. Drug dependence can be rehabilitated medically but rehabilitation does not guarantee that a drug addict will recover from his addiction. Many users, even though they have undergone rehabilitation programs, have not been able to truly leave drug or recover. The purpose of this paper is to find out in detail the factors that influence the relapse behavior of former drug users. The writing method used in this article was a literature review, which searched in 5 international databases were Science Direct, Willey Online Library, Sage Journal, and ProQuest. The author used several search keywords namely "factor"; "Cause"; "Drug", "abuse"; "Substance" and used boolean "AND" and "OR". Based on the 8 articles analyzed, it was found that the causal factors related to the recurrence of drug abuse can be broken down into 7 included individual emotional states, conflict, environment and family, peers, wrong treatment, failed treatment and the desire to return to use. The emotional state, the desire to re-use, family factors and peer influence were the most influential factors. Keywords: relapse; narcotics; caused ABSTRAK Penyalahgunaan Narkotika, Psikotropika dan Zat Adiktif lainya (NAPZA) masih menjadi masalah di kalangan masyarakat. Tren penyalahgunan NAPZA internasional mengalami peningkatan. Ketergantungan narkoba dapat direhabilitasi secara medis namun rehabilitasi tidak menjamin pecandu narkoba akan sembuh dari ketergantungannya. Banyak pengguna yang meskipun telah menjalani program rehabilitasi, namun belum bisa benar-benar meninggalkan NAPZA atau sembuh. Tujuan penulisan ini untuk mengetahui secara merinci faktor yang mempengaruhi perilaku kambuh mantan penyalahguna NAPZA. Metode yang digunakan dalam penulisan artikel ini adalah tinjauan literatur, yakni sebuah pencarian internasional yang menggunakan 5 database Proquest, Science Direct, Willey Online Library, Sage Journal, dan ProQuest. Penulis menggunakan beberapa kata kunci pencarian yaitu “factor”; “cause”; “drug”, “abuse”; “substance”. dengan menggunakann boolean “AND” dan “OR”. Berdasarkan 8 artikel yang dianalisis, didapatkan bahwa faktor penyebab yang berkaitan dengan kekambuhan penyalahgunaan NAPZA dapat di uraikan menjadi 7 antara lain keadaan emosi individu, konflik, lingkungan dan keluarga, rekan sebaya, pengobatan yang salah, pengobatan yang gagal serta keinginan kembali menggunakan. Keadaan emosional, keinginan kembali menggunakan, faktor keluarga dan pengaruh rekan sebaya adalah faktor yang paling berpengaruh. Kata kunci: kekambuhan; NAPZA; penyebab

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Side Effects of Chronic Methadone Use in Opioid Addiction: A Scoping Review on Hematological Derangements

Khalid

Anuar

Ang

et al. 2023

CDS

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Background: Per oral methadone maintenance therapy [MMT] was introduced as part of harm reduction strategy to manage rising numbers of HIV infections caused by intravenous use of illicit drugs. Method: We aim to review published articles related to the side effects of long-term methadone therapy, focusing on hematological derangements in human studies published between 1 January 2000 till 31 January 2021. Results: Our search databases include Web of Science, Scopus, and Medline. Our search yielded 971 articles, of which 55 articles relates to the effects of MMT on various organ systems: cardiovascular [n=12], respiratory [n=1], endocrine [n=10], central nervous system [n=12], neurobehavioral [n=10], gastrointestinal [n=1], bone [n=1]. There were eight articles specifically related to the hematological side effects of chronic methadone therapy that includes [i] immune system hyperactivation, [ii] reduced circulating lymphocytes, and an [iii] increased in blood viscosity. Conclusion: In view of all foreseeable health risks seen with prolonged methadone therapy, pharmacological modulation is warranted to find a better substitute in managing patients with opioid dependence.

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Associated Factors for Relapse in Opioid Addicts undergoing Therapy

Cited by 4 publications

References 0 publications

The risk assessment of relapse among newly enrolled participants in methadone maintenance treatment: A group-LASSO based Bayesian network study

The risk assessment of relapse among newly enrolled participants in methadone maintenance treatment: A group-LASSO based Bayesian network study

Faktor Penyebab Kekambuhan pada Mantan Penyalahguna NAPZA

Side Effects of Chronic Methadone Use in Opioid Addiction: A Scoping Review on Hematological Derangements

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