Associação entre deficiência de vitamina A e situação sociodemográfica de mães e recém-nascidos

Ramalho, Rejane Andréa; Flores, Hernando; Accioly, Elizabeth; Saunders, Cláudia

doi:10.1590/s0104-42302006000300018

Cited by 30 publications

(42 citation statements)

References 13 publications

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“…Corroborating these fi ndings, Wieringa et al 23 (2002) observed an overestimation of the prevalence of VAD of around 4.6% comparing prevalence No link was observed between VAD and socioeconomic and demographic data. According to Ramalho et al, 14 defi ciencies in micronutrients may manifest themselves regardless of economic conditions, as they are also a result of inappropriate dietary habits related to specifi c cultural patterns. With regards to age group, the homogeneous behavior of VAD prevalence in the children in this study does not confi rm a trend observed in other studies with pre-school children, in which younger children showed lower levels of serum retinol.…”

Section: Discussionmentioning

confidence: 99%

Deficiencia de vitamina A e fatores associados em criancas de areas urbanas

et al. 2013

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OBJECTIVE:To estimate the prevalence of vitamin A defi ciency and its associated factors in children. METHODS:A cross-sectional population-based study, involving 1,211 children of both sexes, aged between six and 59 months old, was carried out in the urban zone of 9 cities in the state of Paraiba, Northeastern Brazil. Vitamin A status was assessed by serum retinol levels (high performance liquid chromatography -HPLC) and subclinical infection was assessed by C-reactive protein concentrations. Socioeconomic, demographic and sanitation conditions, as well as vitamin A supplement intake, were also evaluated. Children with serum retinol concentrations RESULTS:The prevalence of vitamin A deficiency was 21.8% (95%CI 19.6;24.2), showing an association with subclinical infection and lack of indoor plumbing. The prevalence of vitamin A defi ciency was 21.8% (95%CI 19.6;24.2). After adjustment, vitamin A defi ciency was found to be linked with subclinical infection and lack of indoor plumbing. Vitamin A defi ciency was four times higher (CI95% 1.49;10.16) in children with subclinical infection whose homes were without indoor plumbing, compared to children who were not infected and with indoor plumbing in their homes. CONCLUSIONS:Despite activities aimed at the prevention and control of vitamin A defi ciency, hypovitaminosis A, remains a public health concern among children under fi ve.

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Section: Discussionmentioning

confidence: 99%

Deficiencia de vitamina A e fatores associados em criancas de areas urbanas

et al. 2013

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“…The primary cause of VAD is insufficient consumption of this vitamin, below the individual's organic needs, thus damaging the physiological functions although clinical signs of the deficiency may not be evident. [21][22][23][24] The second cause of VAD is the frequency of infectious episodes. Nowadays it is known that even subclinical VAD (when xerophthalmia signs are absent) intensifies the severity of infirmities and of several infectious processes, and it may provoke immunodeficiency status of an exclusive nutritional origin added to a higher metabolic utilization of vitamin A against oxidative stress to which individuals with infectious processes are more exposed to.…”

Section: Discussionmentioning

confidence: 99%

Retinol, β-carotene and oxidative stress in systemic inflammatory response syndrome

Nogueira

Borges²,

Lameu

et al. 2015

Rev. Assoc. Med. Bras.

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Objective: patients suffering systemic inflammatory response syndrome (SIRS) constitute a group susceptible to elevated levels of oxidative stress. This study's aim is to evaluate the state of oxidative stress and levels of serum retinol and β-carotene in these patients. Methods: forty-six patients were divided into 2 groups: those those without diet (G1; n=18) and those with enteral nutritional support (G2; n=28). Serum levels of retinol and total carotenoids were measured. C-reactive protein (CRP) levels and Apache scores were also calculated. Oxidative stress was estimated by measuring thiobarbituric acid reactive substance (TBARS) levels. Results: the patients' median age was 66.9 (SD=19.3) years. Lower concentrations of retinol and carotenoids were found in 68.6 and 66.7% of G1, respectively. In G2, despite average vitamin A levels being 8078 + 4035, retinol and β-carotene were considered insufficient (31.2 and 33.4%, respectively). No difference was noted between the 2 groups, according to the variables studied, with the exception being PCR and β-carotene (p=0.002; p=0.01).

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“…Da Silva et al (23) encontraram grande risco de níveis mais baixos de carotenóides em escolares e adolescentes com sobrepeso (OR 2,51; IC95% 1,43-4,39). Diante disso, a literatura é unâni-me ao afirmar que a deficiência da vitamina A, assim como carências de outros micronutrientes, está mais associada ao consumo inadequado de alimentos fontes do que à classificação do estado nutricional antropométrico (16,26) .…”

Section: Discussionunclassified

“…Dados recentes de Ramalho et al (26) apontam a falta de associação entre a deficiência de vitamina A e a condição sociodemográfica. Tal constatação aponta o baixo consumo de vitamina A como o principal fator etiológico em nível epidemiológico.…”

Section: Discussionunclassified

Análise crítica de estudos brasileiros sobre deficiência de vitamina A no grupo materno-infantil

Ramalho

Padilha

Saunders

2008

Rev. paul. pediatr.

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OBJETIVO: Apresentar uma análise crítica de estudos da literatura sobre a deficiência de vitamina A (DVA) no Brasil, segundo o indicador bioquímico retinol sérico, considerando-se o impacto negativo da DVA na saúde reprodutiva e no desenvolvimento infantil. FONTES DE DADOS: os bancos de dados Medline e BVS, no período de 1994 a 2007, foram rastreados com a combinação de descritores: "vitamin A deficiency", "Brazil", "pregnant", "children" e "retinol serum level". A inclusão dos artigos foi realizada com base em critérios de elegibilidade referentes à população, desenho do estudo e idioma, enfatizando-se estudos com gestantes, puérperas, nutrizes, lactentes e pré-escolares que não apresentassem doenças crônicas não-transmissíveis ou infecciosas. SÍNTESE DOS DADOS: dos 27 artigos selecionados, 25 eram estudos transversais, um era caso-controle e um estudo longitudinal. Identificou-se que 71% e 25% dos trabalhos com gestantes e crianças, respectivamente, adotaram valores de retinol sérico <1,05µmol/L como ponto de corte. Todos os estudos apontaram a DVA como um problema de proporção preocupante. Reconhece-se a emergente inserção dos adolescentes no grupo de risco potencial para DVA e da antropometria como variável independente para tal deficiência nutricional. CONCLUSÕES: Aponta-se uma necessidade de incluir estratégias de intervenção adicionais à suplementação, reavaliar pontos de corte na interpretação do diagnóstico da DVA e refletir sobre a pertinência da inclusão de novas áreas e grupos com risco potencial para DVA em programas de intervenção.

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Associação entre deficiência de vitamina A e situação sociodemográfica de mães e recém-nascidos

Cited by 30 publications

References 13 publications

Deficiencia de vitamina A e fatores associados em criancas de areas urbanas

Deficiencia de vitamina A e fatores associados em criancas de areas urbanas

Retinol, β-carotene and oxidative stress in systemic inflammatory response syndrome

Análise crítica de estudos brasileiros sobre deficiência de vitamina A no grupo materno-infantil

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