Assessment of red onion on antioxidant activity in rat

Onion extract (Allium cepaL.), quercetin and catechin up-regulate paraoxonase 1 activity with concomitant protection against low-density lipoprotein oxidation in male Wistar rats subjected to oxidative stress

“…Previous studies have shown that licorice‐derived glabridin can preserve paraoxonase activity during lipoprotein oxidation, and pomegranate juice consumption also increases PON1 arylesterase activity, in association with a reduction in LDL susceptibility to copper ion‐induced oxidation . These results provide evidence of the positive effect of onion extract on PON1 activity and prevention of LDL oxidation during periods of oxidative insult, with improvement in the antioxidant capability of rats, suggesting its value as a dietary antioxidant food . Moreover, quercetin has been previously shown to exert protective effects on ageing of specific tissues in mouse and other cellular models .…”

“…39 These results provide evidence of the positive effect of onion extract on PON1 activity and prevention of LDL oxidation during periods of oxidative insult, with improvement in the antioxidant capability of rats, suggesting its value as a dietary antioxidant food. 44,46 Moreover, quercetin has been previously shown to exert protective effects on ageing of specific tissues in mouse and other cellular models. 47 Quercetin and its derivative, namely quercetin caprylate as a proteasome activator with antioxidant properties has been reported to influence cellular lifespan, survival and viability of Human foetal lung fibroblast, cell lines derived from a 16-18 week old human foetus (HFL-1) primary human fibroblasts.…”

Antioxidant activity of phenolic extracts from different cultivars of Italian onion (Allium cepa) and relative human immune cell proliferative induction

“…Recent literature is rich in both in vivo and in vitro studies reporting the antithrombotic (Lee et al, 2013), hypolipidemic (Lee et al, 2012b;Srinivasan, 2013), antidiabetic (Jung et al, 2011), antiobesity (Yoshinari et al, 2012), antioxidant (Alpsoy et al, 2013;Lee et al, 2012a), anti-inflammatory (Dorsch et al, 1990), cancer chemopreventive (Wang et al, 2012), and antiparasitic (Aboelhadid et al, 2013;Klimpel et al, 2011) properties of onion bulb extracts. Moreover, accumulated epidemiological studies suggest that a diet rich in onions may also have favorable effects on the risk of acute myocardial infarction (Galeone et al, 2009), and benign prostatic hyperplasia (Galeone et al, 2007).…”

Semen quality characteristics of Koekoek breeder cocks influenced by supplemental inclusion levels of onion and garlic mixture at 35-41 weeks of age

“…One of the major issues on breeding in farm animals is infertility, and approximately 30% of the problems are related to the males (Khaki et al, 2009;Lee et al, 2012;Barkhordari et al, 2013). Recently, a wide number of plantderived pharmaceutical products are now being used in traditional medicine because of their beneficial properties in handling infertility (Yama et al, 2011).…”