2005
DOI: 10.1159/000326148
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Assessment of Micronucleus Frequency in Normal Oral Mucosa of Patients Exposed to Carcinogens

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Cited by 38 publications
(36 citation statements)
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“…Also, the effect of age on micronuclei formation in buccal cells is unclear. In five investigations, no effect was detected (6,13,27,29,30); in two, an increase with age (39,40) and in another a decrease with age (25) were detected. Piyathilake et al (40) reported that the frequencies of micronucleated cells are 2.8-fold higher in females after adjusting for race, age, smoking habit, and levels of selected vitamin, whereas in a Brazilian study (27) the number of micronuclei was significantly (i.e., >3-fold) higher in males.…”
Section: Discussionmentioning
confidence: 86%
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“…Also, the effect of age on micronuclei formation in buccal cells is unclear. In five investigations, no effect was detected (6,13,27,29,30); in two, an increase with age (39,40) and in another a decrease with age (25) were detected. Piyathilake et al (40) reported that the frequencies of micronucleated cells are 2.8-fold higher in females after adjusting for race, age, smoking habit, and levels of selected vitamin, whereas in a Brazilian study (27) the number of micronuclei was significantly (i.e., >3-fold) higher in males.…”
Section: Discussionmentioning
confidence: 86%
“…Although some investigators (6,13,26,27,30) found no effect of alcohol on micronuclei formation, Gabriel et al (31) showed a significant effect. Also, Stich and Rosin (26) reported on a pronounced synergistic effect of alcohol in combination with smoking, whereas in another study (25) even an inverse relation was found.…”
Section: Discussionmentioning
confidence: 97%
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“…Este resultado sugere que esta estrutura não está relacionada à genotoxicidade. A ausência de associação positiva entre broken eggs e insulto genotóxico também foi relatada por diversos autores (BOHRER et al, 2005;CERQUEIRA et al, 2008;HOLLAND et al, 2008;TORRES-BUGARÍN et al, 2003). Segundo Holland et al (2008) broken eggs está relacionado com amplificação gênica e não representa danos ao DNA.…”
Section: Discussionunclassified
“…Segundo Holland et al (2008) broken eggs está relacionado com amplificação gênica e não representa danos ao DNA. Torres-Bugarín et al (2003) e Bohrer et al (2005) corroboram esta hipótese e salientam que estas estruturas estão associadas ao processo normal de diferenciação celular.…”
Section: Discussionunclassified