Assessment of Human Dental Pulp Stem Cells With Chitosan Scaffold Versus Xenografts in Implant Osseointegration. An Experimental Study in a Rabbit Model

Kamal, Abeer; Khalil, Eman

doi:10.21608/edj.2018.91762

Cited by 4 publications

(3 citation statements)

References 2 publications

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“…Kamal and colleagues applied stem cells and xenografts to the implant sockets without placing dental implants. As a result, they found higher osseointegration in the subjects who received stem cell group and xenograft 39. Menicucci et al40 suggested that they observed delayed bone formation in the presence of xenogenic material 12 months after sinus grafting in humans.…”

Section: Discussionmentioning

confidence: 97%

“…As a result, they found higher osseointegration in the subjects who received stem cell group and xenograft. 39 Menicucci et al 40 suggested that they observed delayed bone formation in the presence of xenogenic material 12 months after sinus grafting in humans. But Schmitt et al 41 reported that the use of xenograft did not endanger the long-term survival of the implant when the titanium implant was placed by grafting.…”

Section: Discussionmentioning

confidence: 99%

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Osseointegration Levels of Implants Placed With Allogenic and Xenogenic Bone Ring: An Experimental Biomechanical Analysis

Gül

Bozoğlan

Dündar

et al. 2022

Journal of Craniofacial Surgery

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This in vivo study aimed to do a biomechanical analysis of the early period bone-implant connection of titanium implants simultaneously inserted with xsenogenic and allogenic bone ring. In this study, 28 Sprague Dawley female rats were used. Four rats were killed to obtain an allogenic bone ring, and after this, the remaining rats were divided into control (n = 8), xsenogenic (n = 8), and allogenic (n = 8) bone ring groups. Titanium-machined surfaced implants were integrated right tibias of the rats. In controls, only implants were integrated into right tibias. In the greft groups, the implants were integrated simultaneously with bone rings. After 2 weeks of the experimental period, the rats were killed ,and titanium implants and surrounding bone tissues were removed for biomechanic analysis. After biomechanical reverse torque analysis bone-implant connection was determined as Newton/cm 2 ; in controls 3.26 (1.2 to 4.5), in allogenic ring group 3.37 (2 to 4.4), in xsenogenic ring group 5.93 (2.8 to 10). Statistically significant differences were not detected between the groups (P > 0.05). Within the limitation of this study, both allogenic and xsenogenic bone grafts could be successfully used in bone augmentation in implant surgery.

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Osseointegration Levels of Implants Placed With Allogenic and Xenogenic Bone Ring: An Experimental Biomechanical Analysis

Gül

Bozoğlan

Dündar

et al. 2022

Journal of Craniofacial Surgery

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“…[47]. For example, Kamal and Khalil (2018) [48] used CHS with DPSCs to evaluate the potential for bone formation around dental implants. They noted that this method helped bone maturation around the implant, suggesting its potential use in bone regeneration [48].…”

Section: Natural Biomaterialsmentioning

confidence: 99%

A Molecular View on Biomaterials and Dental Stem Cells Interactions: Literature Review

et al. 2022

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Biomaterials and stem cells are essential components in the field of regenerative medicine. Various biomaterials have been designed that have appropriate biochemical and biophysical characteristics to mimic the microenvironment of an extracellular matrix. Dental stem cells (DT-MSCs) represent a novel source for the development of autologous therapies due to their easy availability. Although research on biomaterials and DT-MSCs has progressed, there are still challenges in the characteristics of biomaterials and the molecular mechanisms involved in regulating the behavior of DT-MSCs. In this review, the characteristics of biomaterials are summarized, and their classification according to their source, bioactivity, and different biological effects on the expansion and differentiation of DT-MSCs is summarized. Finally, advances in research on the interaction of biomaterials and the molecular components involved (mechanosensors and mechanotransduction) in DT-MSCs during their proliferation and differentiation are analyzed. Understanding the molecular dynamics of DT-MSCs and biomaterials can contribute to research in regenerative medicine and the development of autologous stem cell therapies.

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Preparation and application of chitosan biomaterials in dentistry

Zhang

Hui²,

Du³

et al. 2021

International Journal of Biological Macromolecules

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Assessment of Human Dental Pulp Stem Cells With Chitosan Scaffold Versus Xenografts in Implant Osseointegration. An Experimental Study in a Rabbit Model

Cited by 4 publications

References 2 publications

Osseointegration Levels of Implants Placed With Allogenic and Xenogenic Bone Ring: An Experimental Biomechanical Analysis

Osseointegration Levels of Implants Placed With Allogenic and Xenogenic Bone Ring: An Experimental Biomechanical Analysis

A Molecular View on Biomaterials and Dental Stem Cells Interactions: Literature Review

Preparation and application of chitosan biomaterials in dentistry

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