Assessment of Health-Related Quality of Life of Patients after Kidney Transplantation in Comparison with Hemodialysis and Peritoneal Dialysis

Czyżewski, Łukasz; Sańko-Resmer, Joanna; Wyzgał, Janusz; Kurowski, Andrzej

doi:10.12659/aot.891265

Cited by 107 publications

(60 citation statements)

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“…The scores obtained with the KDQOL‐SF for patients receiving RRT generally show better HRQL results than those obtained in the present study (Kurowski ). These considerations highlight the important impact produced when patients with CKD start dialysis, and show that special attention should be devoted to treating and alleviating the symptoms that may directly affect HRQL.…”

Section: Discussioncontrasting

confidence: 58%

Depression, anxiety and health‐related quality of life amongst patients who are starting dialysis treatment

Rubio

Morales-Asencio

Raventos³

2017

Journal of Renal Care

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S U M M A R YBackground: Chronic kidney disease (CKD) has a severe impact on patients' health-related quality of life (HRQL). The start of renal replacement therapy (RRT) significantly influences psychological, physical and social aspects of life. Objectives: To analyse the HRQL and psychological status (anxiety and depression) at the start of RRT. Methods: We undertook an observational descriptive cross-sectional study. A total of 152 patients starting RRT were recruited for the study. HRQL was measured by the Kidney Disease and Quality of Life Short Form questionnaire. Levels of anxiety and depression were assessed by the Hospital Anxiety and Depression Scale questionnaire. Comorbidities and sociodemographic and clinical factors were also evaluated. Findings: HRQL in patients with end-stage kidney disease (ESKD) is significantly affected by the initiation of RRT in all respects. States of anxiety and depression were present in 26.6% and 27% of patients, respectively. These states are significantly related to the emotional component of the quality of life. Conclusion: The initiation of RRT has a strong impact on HRQL in comparison with a reference population and with other stages of CKD. The early detection of an altered psychological state is important, as this condition should be treated from the first stages of the disease, as it can significantly affect the subsequent development of RRT and the patient's quality of life.

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Section: Discussioncontrasting

confidence: 58%

Depression, anxiety and health‐related quality of life amongst patients who are starting dialysis treatment

Rubio

Morales-Asencio

Raventos³

2017

Journal of Renal Care

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“…[1–3] KT also confers benefits to society because it incurs less health care expenditure compared with dialysis. [4] However, KT may not be suitable for every candidate, [5] and progressing from the ESRD diagnosis through dialysis to referral to evaluation, wait-listing, and transplantation requires the efforts of both physicians and patients.…”

Section: Introductionmentioning

confidence: 99%

Factors affecting willingness to receive a kidney transplant among hemodialysis patients in West China

Tan

Song²,

Jiang³

et al. 2017

Medicine

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Many factors are associated with the willingness of ESRD patients to receive a kidney transplant. No data are available for patients in China. The study aim was to describe the attitudes toward transplantation in a cohort of patients at a single dialysis center in China.A study questionnaire derived from previously published literature was completed by 239 hemodialysis outpatients. Factors associated with willingness to receive a transplant were identified by univariate and multivariate logistic regression analyses.The respondents were primarily men 50.7 ± 15.1 years of age; 46.4% were willing to receive a transplant. Younger age (OR = 0.928, 95% CI: 0.898–0.959), good self-reported health (OR = 0.203, 95% CI: 0.081–0.51), and awareness of the benefits of transplantation (OR = 0.195, 95% CI: 0.083–0.456) were less likely to deny the transplant. Patients ≤60 years of age were about 13 times more likely to favor transplantation than those >60 years of age (OR = 12.99, 95% CI: 3.75–45.45). For every 10 years under 60, participants were 2.16 times more willing to receive a kidney transplant (OR = 2.16, 95% CI: 1.53–3.02). Older patients were also less likely to be referred for evaluation (OR = 0.955, 95% CI: 0.923–0.989, P = .009).The percentage of ESRD patients in China, particularly older patients, who are willing to accept a transplant, is relatively low. A better understanding of the benefits of transplantation is needed to increase their acceptance.

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“…These differences between hemodialysis and kidney transplantation may be indicative of the considerable improvements in quality of life achieved through kidney transplant. The overriding goal for kidney transplant recipients was to protect their graft to maintain their quality of life and remain free from the constraints and distress of dialysis (46,47). …”

Section: Discussionmentioning

confidence: 99%

“…Compared with other Delphi surveys used to establish core outcomes, our sample size is large with a broad representation of different stakeholders across 79 countries and had a high response rate of 77% by round 3 (46,47). Our findings also included qualitative data to provide further insights into the meaning, reasons and interpretations of the outcomes by participants.…”

Section: Discussionmentioning

confidence: 99%

Developing Consensus-Based Priority Outcome Domains for Trials in Kidney Transplantation

et al. 2017

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Background Inconsistencies in outcome reporting and frequent omission of patient-centered outcomes can diminish the value of trials in treatment decision-making. We identified critically important outcome domains in kidney transplantation based on the shared priorities of patients/caregivers and health professionals. Methods In a 3-round Delphi survey, patients/caregivers and health professionals rated the importance of outcome domains for trials in kidney transplantation on a 9-point Likert scale and provided comments. During Round 2 and 3, participants rerated the outcomes after reviewing their own score, the distribution of the respondents’ scores, and comments. We calculated the median, mean, and proportion rating 7–9 (critically important), and analyzed comments thematically. Results 1018 participants (461 [45%] patients/caregivers and 557 [55%] health professionals) from 79 countries completed Round 1, and 779 (77%) completed Round 3. The top 8 outcomes that met the consensus criteria in Round 3 (mean ≥7.5, median ≥8 and proportion >85%) in both groups were graft loss, graft function, chronic rejection, acute rejection, mortality, infection, cancer (excluding skin) and cardiovascular disease. Compared with health professionals, patients/caregivers gave higher priority to 6 outcomes (mean difference of 0.5 or more): skin cancer, surgical complications, cognition, blood pressure, depression, and ability to work. We identified 5 themes: capacity to control and inevitability, personal relevance, debilitating repercussions, gaining awareness of risks, and addressing knowledge gaps. Conclusions Graft complications and severe comorbidities were critically important for both stakeholder groups. These stakeholder-prioritized outcomes will inform the core outcome set to improve the consistency and relevance of trials in kidney transplantation.

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Assessment of Health-Related Quality of Life of Patients after Kidney Transplantation in Comparison with Hemodialysis and Peritoneal Dialysis

Cited by 107 publications

References 0 publications

Depression, anxiety and health‐related quality of life amongst patients who are starting dialysis treatment

Depression, anxiety and health‐related quality of life amongst patients who are starting dialysis treatment

Factors affecting willingness to receive a kidney transplant among hemodialysis patients in West China

Developing Consensus-Based Priority Outcome Domains for Trials in Kidney Transplantation

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