Assessment of health-related quality of life in end-stage chronic obstructive pulmonary disease and non-small-cell lung cancer patients in Serbia

Marić, Dragana; Jovanović, Dragana; Nagorni-Obradović, Ljudmila; Stjepanović, Mihailo; Kisić-Tepavčević, Darija; Pekmezović, Tatjana

doi:10.1017/s1478951515000589

Cited by 9 publications

(27 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Gore et al's lung cancer sample differed from Bausewein et al's in terms of being mostly (72%) men and having received palliative care radiotherapy over the last 12 months in 80% of cases. It was less clear what might have led other studies to differ from the majority by finding depression to be worse in COPD 34,35 or anxiety to be worse in lung cancer, 13 and betweengroup differences in these studies were either mixed 13,34 or less than the 0.5 SD taken to suggest a clinically important difference. 35 As noted above, most studies measuring pain found this to be worse in lung cancer than COPD.…”

Section: Synthesis Of Resultsmentioning

confidence: 87%

A systematic review and meta-analysis of studies comparing burden from lung cancer and chronic obstructive pulmonary disease

Luckett

Martin²,

Currow

et al. 2020

Palliat Med

View full text Add to dashboard Cite

Background: Chronic obstructive pulmonary disease and lung cancer are both life-limiting diseases that confer burden in the form of symptoms and affect functioning and quality of life. Comparing burden between these diseases is of interest to determine whether people with chronic obstructive pulmonary disease require improved access to Specialist Palliative Care. Access should be based on needs rather than diagnosis or prognosis but is limited for people with chronic obstructive pulmonary disease compared to lung cancer. Aim: The aim of this study was to synthesise research comparing burden from chronic obstructive pulmonary disease and lung cancer to estimate relative need for Specialist Palliative Care. Design: A systematic review was conducted of observational quantitative studies published in English peer-reviewed journals comparing burden from chronic obstructive pulmonary disease and lung cancer (PROSPERO CRD42018108819). No limits were placed on disease stage. Meta-analyses were performed where studies used the same measure; otherwise, synthesis used a narrative approach. Risk of bias was assessed using the Agency for Healthcare Research and Quality tool. Data sources: Electronic databases were searched in September 2019. Results: Of 790 articles returned, 13 were included, reporting 11 studies. Risk of bias was generally moderate. Except for pain, burden tended to be at least as substantial from chronic obstructive pulmonary disease as from lung cancer, with breathlessness and impacts on functioning being significantly worse. Longitudinal studies suggest that people with chronic obstructive pulmonary disease live with burden for longer. Conclusion: Efforts should be made to ensure that access to Specialist Palliative Care is commensurate with chronic obstructive pulmonary disease’s substantial and long-lasting burden. Future research should clarify whether managing burden in chronic obstructive pulmonary disease and lung cancer requires different approaches.

show abstract

Section: Synthesis Of Resultsmentioning

confidence: 87%

A systematic review and meta-analysis of studies comparing burden from lung cancer and chronic obstructive pulmonary disease

Luckett

Martin²,

Currow

et al. 2020

Palliat Med

View full text Add to dashboard Cite

show abstract

“…Habraken et al 2 reported similar health-related quality of life between those with COPD or lung cancer, with the COPD group reporting significantly lower scores in physical functioning and general health perceptions. Maric et al 25 found COPD patients scored significantly lower in all SF-36 domains except for pain. Hasegawa et al 23 reported similar scores in the McGill Quality of Life questionnaire but those with COPD had a better psychological state and lung cancer patients had a better support state.…”

Section: Resultsmentioning

confidence: 96%

“…Eleven studies 2,3,5,18–25 compared a population with lung cancer to a population with COPD and consisted of retrospective studies of deceased populations ( n = 5), cross-sectional studies ( n = 3), prospective cohort studies ( n = 2) and post-bereavement interviews with caregivers ( n = 1). Three retrospective studies compared a population with COPD to a population with lung cancer of which a proportion (17%–42%) also had co-existing COPD.…”

Section: Resultsmentioning

confidence: 99%

“…Four studies compared health-related quality of life with three studies using the 36-item Short Form Health Survey (SF-36) 2,22,25 and one study using the McGill Quality of Life Questionnaire. 23 Gore et al 22 reported significantly lower scores for patients with severe COPD, reflecting worse health-related quality of life, in all domains except physical and emotional functioning.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Comparison of end-of-life care in people with chronic obstructive pulmonary disease or lung cancer: A systematic review

et al. 2020

View full text Add to dashboard Cite

Background: Palliative care has been widely implemented in clinical practice for patients with cancer but is not routinely provided to people with chronic obstructive pulmonary disease. Aim: The study aims were to compare palliative care services, medications, life-sustaining interventions, place of death, symptom burden and health-related quality of life among chronic obstructive pulmonary disease and lung cancer populations. Design: Systematic review with meta-analysis (PROSPERO: CRD42019139425). Data sources: MEDLINE, EMBASE, PubMed, CINAHL and PsycINFO were searched for studies comparing palliative care, symptom burden or health-related quality of life among chronic obstructive pulmonary disease, lung cancer or populations with both conditions. Quality scores were assigned using the QualSyst tool. Results: Nineteen studies were included. There was significant heterogeneity in study design and sample size. A random effects meta-analysis ( n = 3–7) determined that people with lung cancer had higher odds of receiving hospital (odds ratio: 9.95, 95% confidence interval: 6.37–15.55, p < 0.001) or home-based palliative care (8.79, 6.76–11.43, p < 0.001), opioids (4.76, 1.87–12.11, p = 0.001), sedatives (2.03, 1.78–2.32, p < 0.001) and dying at home (1.47, 1.14–1.89, p = 0.003) compared to people with chronic obstructive pulmonary disease. People with lung cancer had lower odds of receiving invasive ventilation (0.26, 0.22–0.32, p < 0.001), non-invasive ventilation (0.63, 0.44–0.89, p = 0.009), cardiopulmonary resuscitation (0.29, 0.18–0.47, p < 0.001) or dying at a nursing home/long-term care facility (0.32, 0.16–0.64, p < 0.001) than people with chronic obstructive pulmonary disease. Symptom burden and health-related quality of life were relatively similar between the two populations. Conclusion: People with chronic obstructive pulmonary disease receive less palliative measures at the end of life compared to people with lung cancer, despite a relatively similar symptom profile.

show abstract

“…Although the prevalence of chronic diseases in cancer patients is substantial (62), we excluded patients chronic diseases' comorbidity since several studies showed that chronic diseases, such as stroke, COPD or chronic kidney disease, significantly further decreases HRQoL in cancer patients (50,(63)(64)(65), A study from Serbia showed that cancer patient with complications showed a higher level of depressive symptoms (65). There was also a substantial reduction on physical and social functioning of breast cancer patients with chronic disease complications (50).…”

Section: Discussionmentioning

confidence: 99%

Health-Related Quality of Life of Patients with HPV-Related Cancers in Indonesia

Setiawan

Dusafitri

Galistiani

et al. 2018

Value in Health Regional Issues

View full text Add to dashboard Cite

show abstract

Assessment of health-related quality of life in end-stage chronic obstructive pulmonary disease and non-small-cell lung cancer patients in Serbia

Abstract: A worse QoL, a significantly higher level of depressive symptoms, and adverse socioeconomic status in the COPD group imposes the need for development of more intensive psychosocial and community support for COPD patients during implementation of palliative care.

Cited by 9 publications

References 37 publications

A systematic review and meta-analysis of studies comparing burden from lung cancer and chronic obstructive pulmonary disease

A systematic review and meta-analysis of studies comparing burden from lung cancer and chronic obstructive pulmonary disease

Comparison of end-of-life care in people with chronic obstructive pulmonary disease or lung cancer: A systematic review

Health-Related Quality of Life of Patients with HPV-Related Cancers in Indonesia

Contact Info

Product

Resources

About