“…[10,11,[13][14][15][16] The risk of depression at the Cushing disease patients is higher than the risk of this psychiatric manifestation at other pituitary affections. Symptoms noticed at Cushing patients were: psycho-emotional lability, physical and psychical asthenia, loss of initiative, inhibition, tendency of social isolation, amnesic difficulties, mania, psychosis, irritability, depressive ideation, panic attack, fatigue, anxiety, maladaptive personality [12,[17][18][19][20][21].…”