2007
DOI: 10.1016/j.jep.2006.08.015
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Assessment of antidiarrhoeal activity of the methanol extract of Xylocarpus granatum bark in mice model

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Cited by 42 publications
(41 citation statements)
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References 37 publications
(32 reference statements)
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“…This result is in agreement to the findings of Bakeri et al 16 who reported that, 200 and 400mg/kg aqueous leave extract of Momordica charantia in rats like the standard drug, morphine significantly inhibited the frequency of defecation compared to control. It also supports the previous claims that antidiarrhoeal plants are known to reduce number of wet stools as reported for Eremomastax speciosa and Xylocarpus granatum 36,37 . The preventive capacity of this plant, makes it beneficial as preventive agent.…”
Section: Discussionsupporting
confidence: 90%
“…This result is in agreement to the findings of Bakeri et al 16 who reported that, 200 and 400mg/kg aqueous leave extract of Momordica charantia in rats like the standard drug, morphine significantly inhibited the frequency of defecation compared to control. It also supports the previous claims that antidiarrhoeal plants are known to reduce number of wet stools as reported for Eremomastax speciosa and Xylocarpus granatum 36,37 . The preventive capacity of this plant, makes it beneficial as preventive agent.…”
Section: Discussionsupporting
confidence: 90%
“…This activity was reverse dose dependent. The result of this experiment could be due to two types of receptors which appeared to be involved in extracts action on gastrointestinal tract: high and low affinity receptor subtypes sensitive to low and high agonist concentrations, which induced contraction and relaxation of smooth muscles respectively as found by Rouf et al (2007) and Jalilzadeh-Amin et al (2012) that the effect of aqueous peel extract is dose depended. Therefore, probably P.granatum peels extracts at low doses increased the reabsorption of NaCl and water by decreasing intestinal motility as observed by the decrease in intestinal transit by charcoal meal and by their anticholinergic and antihistaminic effects.…”
Section: Advances In Animal and Veterinary Sciences March 2016 | Volumentioning
confidence: 79%
“…The Indians use the fruit to treat swellings of breast and also elephantiasis. Preliminary screening reports on various parts of the plant (leaves, bark, stem and root) were found to possess activities like antimicrobial, antimalarial, antifilarial, antiulcer, antidiarrhoeal, fungicidal, cancer and wound healing [8][9][10][11][12][13][14][15] . Keeping in view the limitations of available cardiotonics and folkloric claims on the plant, the present study has been undertaken to scan and evaluate the cardiotonic activity of Xylocarpus granatum.…”
Section: Introductionmentioning
confidence: 99%