Assessing manganese nanostructures based carbon nanotubes composite for the highly sensitive determination of vitamin C in pharmaceutical formulation

Hameed, Sadaf; Munawar, Anam; Khan, Waheed S.; Mujahid, Adnan; Ihsan, Ayesha; Rehman, Asma; Ahmed, Ishaq; Bajwa, Sadia Z.

doi:10.1016/j.bios.2016.10.005

Cited by 30 publications

(12 citation statements)

References 41 publications

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“…Their study shows that carbon‐base electrodes can be applied on a large scale such as in clinical, biomedical, and point of care diagnostics. This statement is supported by their review on small biomolecules such as metabolite, [33,34] amino acids, [35,36] lipids, [37] vitamins, [38,39] and big molecules such as nucleic acids, [40,41] protein, [42] and enzymes [43] . The electrochemical methods used were varied such as Square Wave Voltammetry (SWV), Cyclic Voltammetry (CV), and Different Pulse Voltammetry (DPV).…”

Section: Carbon‐based Electrodesmentioning

confidence: 99%

A Review on Carbon‐based Electrodes for Electrochemical Sensor of Quinolone Antibiotics

et al. 2022

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Quinolone antibiotic is known for its effectiveness in treating infectious disease, and has been used widely for humans and also in animals. Continuous use of antibiotics could promote antibiotic resistance as well as result in the accumulation of antibiotic residues in food. Therefore, monitoring the quinolone antibiotic is important. Meanwhile, carbon‐based electrode is known as a material that has been used widely for electrochemical sensor application. It has been used in its bare form and modified form to improve the electrode catalytic performance. In this review, we summarize the utilization of unmodified and modified carbon‐based electrode in detecting various types of quinolone antibiotics. It is expected to provide comprehensive information on related topics.

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Section: Carbon‐based Electrodesmentioning

confidence: 99%

A Review on Carbon‐based Electrodes for Electrochemical Sensor of Quinolone Antibiotics

et al. 2022

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“…Their potential application in the delivery of CRISPR technologies is not the exception since inorganic nanostructured carriers can carry high loads, improve the stability of the transported cargoes, and facilitate cellular uptake and specific sub-cellular targeting [146,217,218]. Additionally, it is possible to conjugate inorganic nanostructured carriers with different types of biomolecules superficially, such as antibodies, polymers, vitamins and proteins, and peptides [146,[217][218][219] to improve cell penetration and endosomal escape. Functionalization of nanomaterials with translocating proteins or peptides such as OmpA, Buf-II, INF7, and GALA helps to escape an important fraction of endosomal compartments upon cell internalization, which can enhance transfection efficiencies in gene delivery applications [146,173,220].…”

Section: Delivery Carriers To Improve the Performance Of Crispr/cas9-...mentioning

confidence: 99%

Understanding the Potential of Genome Editing in Parkinson’s Disease

Arango

Bittar

Esmeral

et al. 2021

IJMS

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CRISPR is a simple and cost-efficient gene-editing technique that has become increasingly popular over the last decades. Various CRISPR/Cas-based applications have been developed to introduce changes in the genome and alter gene expression in diverse systems and tissues. These novel gene-editing techniques are particularly promising for investigating and treating neurodegenerative diseases, including Parkinson’s disease, for which we currently lack efficient disease-modifying treatment options. Gene therapy could thus provide treatment alternatives, revolutionizing our ability to treat this disease. Here, we review our current knowledge on the genetic basis of Parkinson’s disease to highlight the main biological pathways that become disrupted in Parkinson’s disease and their potential as gene therapy targets. Next, we perform a comprehensive review of novel delivery vehicles available for gene-editing applications, critical for their successful application in both innovative research and potential therapies. Finally, we review the latest developments in CRISPR-based applications and gene therapies to understand and treat Parkinson’s disease. We carefully examine their advantages and shortcomings for diverse gene-editing applications in the brain, highlighting promising avenues for future research.

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“…This chemical reaction takes place between a restrained ligand and analyte of interest that measurably affect the transduced signal, such as an electrical current or potential. 44 This electrochemical signal is directly quantied and related to the presence of marker of interest/ analyte in the sample solution. Electrochemical detection approaches have different subtypes on the basis of signal types like potentiometry, voltammetry, amperometry, and electrochemical impedance spectroscopic.…”

Section: Electrical Detectionmentioning

confidence: 99%